diff --git a/CHANGELOG.md b/CHANGELOG.md
index 5d139a9ac0e6..263b88c96726 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -20,6 +20,7 @@
 
 ### Fixes
 
+- `[jest-cli]` Interrupt tests if interactive watch plugin key is pressed ([#7222](https://github.com/facebook/jest/pull/7222))
 - `[jest-cli]` Fix coverage summary reporting ([#7058](https://github.com/facebook/jest/pull/7058))
 - `[jest-each]` Add each array validation check ([#7033](https://github.com/facebook/jest/pull/7033))
 - `[jest-haste-map]` [**BREAKING**] Replace internal data structures to improve performance ([#6960](https://github.com/facebook/jest/pull/6960))
diff --git a/packages/jest-cli/src/watch.js b/packages/jest-cli/src/watch.js
index 67e78ffa66e1..ed558414f516 100644
--- a/packages/jest-cli/src/watch.js
+++ b/packages/jest-cli/src/watch.js
@@ -321,6 +321,10 @@ export default function watch(
     ).find(plugin => getPluginKey(plugin, globalConfig) === key);
 
     if (matchingWatchPlugin != null) {
+      if (isRunning) {
+        testWatcher.setState({interrupted: true});
+        return;
+      }
       // "activate" the plugin, which has jest ignore keystrokes so the plugin
       // can handle them
       activePlugin = matchingWatchPlugin;