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#53: What is Inflammation? | The CIA's "Finders" Operation | Using Progesterone | CO2 and Stem Cells [LZLAmwBObdA].vtt
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WEBVTT
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Now, Georgie Smallbox, Ray Peat, thank you guys for joining us today.
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We're a little, I think, earlier than what I said, but Ray, can you continue on that thought?
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We were talking about Bitcoin, we were talking about inflation, and we were just talking about the general price increasing of goods, and you had some thoughts on that.
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Yeah, the interest-free money that has been saving the economy for a few years, I think last, at the end of fall of 2019,
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it was reaching the point where just free money, loans, wasn't enough. They had to figure out some way to radically change things, bringing on the pandemic, or more wars, or something was needed.
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I think the basic universal income is going to be phased in gradually with these.
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I think the checks to the public are going to get more often until finally it's like everyone is on a pension.
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That will make savings worthless.
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I see that as once you have everyone basically on a pension, plus inflation that has destroyed any kind of savings,
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then you have people under control because then you can just change their pension at will.
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And you had a specific time frame, you just said four to five years, so that's actually pretty useful to know, I feel like.
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What makes you think four to five years?
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Just the rate of increasing inflation over the last two years or so.
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One of the websites you mentioned, Zero Hedge, they keep talking about inflation and they keep saying, "Oh, maybe people should start buying gold."
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But then I remember that up until 1964, the government had actually prohibited people from owning gold.
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Do you think something like that can happen again?
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Well, there won't be enough gold. It's already tending to disappear like the U.S.
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Won't give back national gold that they were supposedly storing because it just isn't there.
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People have been investing in paper gold and I think there just isn't enough real gold left.
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The price will just go up if it isn't artificially held down like the government has been doing.
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So the price of gold will go up, but there just isn't enough real gold to work as money anymore.
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Remember the Senator Ron Paul, the former Senator?
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For decades he kept saying, "There is no gold at Fort Knox. They refuse to allow me to do an inspection.
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They keep doctoring the paperwork. We have only 1% of the physical gold that the United States claims that it does."
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Do you think there's any truth to that?
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Yes. Germany and Venezuela, for example, were asking to get their gold that had been stored for them in the U.S.
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I haven't heard, but I was paying attention to it for a while and the U.S. was simply stonewalling.
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Do you think that may be one of the reasons why countries like Russia and China are rapidly increasing their physical gold reserves,
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preparing for the devaluation of the dollar basically becoming worthless?
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Yes, I think so.
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We talked about it a little bit, but the idea behind Bitcoin is that it's finite, there's a limited amount,
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and then some people are saying it's a lot better than gold.
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It seems to be getting some institutional support, but you think this is just some kind of misdirection?
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I think so.
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Actually, there's nothing existing. It's a belief system.
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Right now, the changing beliefs about it have made some people very rich,
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but buying a small amount skyrocketed in price.
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Since it's basically a psychological currency, I think it can be manipulated out of existence whenever the world powers decide to.
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In your view, is there any way to hedge your bets against the next four or five years of things getting really rough, monetarily-wise?
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No, not really.
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If you have some land in a place that is survivable, enough water to support yourself,
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and some goats and chickens, and to grow some vegetables, then everything is good until some mobsters or governments decide to confiscate your land.
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People accuse George and I of being a doomer on this subject,
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but when we talk to you, it really seems like things are not going to pick up anytime soon.
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They're just going to get a lot worse.
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I know you choose your words very carefully, and you think about these subjects a lot.
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I imagine you wouldn't even want to say things would get bad,
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just because that might put somebody in a learned helplessness situation.
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Also, I was reading some Lennon quotes, and I think he has a quote about saying you're a true friend to somebody
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if you actually tell them the truth rather than sugarcoating it or something like that.
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What is your perspective on that?
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There is a way out, and that is for everyone or at least half of the population to wake up and actually think about things
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instead of prejudices that they've been taught since childhood.
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If they just start questioning basically every word in their language and thinking, "Why do I think this?"
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and then looking at what the absence of facts in their belief system implies,
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that could lead to people asking questions.
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What can we do about the situation in which a few thousand people are deliberately destroying everyone's livelihood,
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making them rapidly more dependent and threatening bigger and bigger wars to keep people fearful?
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If millions of people start thinking about what can be done, then naturally basic intelligence is going to come up with some ideas.
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What about the tactic of Gandhi, like non-violent non-cooperation?
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Do you think if a sufficient number of people simply refuse to participate in the system, that would be enough to cripple it?
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Yeah, at some point, if there are enough people.
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What would be a few things that would really put a dent into the system,
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like maybe refusing to participate in social media, refusing to buy things online maybe?
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Just absolute withdrawal from all of the stupid imposed digital systems.
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Don't buy anything from Amazon. Don't express your opinions on Facebook.
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Which would require you meeting people physically, which would quickly end the pandemic restrictions,
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because if everybody decides to meet others, you just can't lock them all up?
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Yeah, that's why people ordered not to meet in groups bigger than five or ten.
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That used to be called sedition if you had five or six people gathering together on the street to talk about politics.
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Was there an actual law like that in Britain or the US?
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Oh, in England at different times, when they were very worried about the French or American revolutions spreading.
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Wow, so this has some serious historical roots. It didn't come out of nowhere.
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Well, at the risk of bumming everybody out, I do want to talk more about this, but I do want to jump into your newsletter, Ray.
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Okay, let me scroll down here really quickly.
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Okay, so you have a new newsletter. We talked about your newsletter last time, but this one's called "Inflammation, Adaptation, and Aging."
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And similar to last time, what was your motivation specifically for writing this?
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This seems to connect very closely to the last few newsletters that you've been writing.
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Yeah, and it's a step to the next one, which will be how purpose and intentionality relate to development and inflammation and aging.
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And this is just making the connections between heredity, adaptation, aging and inflammation, and disease resistance.
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Can we get a—sorry, go ahead.
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Bringing in the fact that the perfect environment is intrauterine, and then various things can go wrong after birth.
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If you're in a hospital especially, they can intensify everything that ordinarily would take 50 or 60 years to go wrong.
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They can do it in a couple of weeks, but it's showing the historical continuity between stress, adaptation, and the immune system or developmental system that goes wrong in aging.
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It's really popular in the health world to say, "Oh, that's because of inflammation," or "Oh, that's because of inflammation."
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And it's never really nailed down what inflammation is.
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So what, in your perspective, how do you even define that?
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It's what a healthy person who catches, for example, the COVID virus does not experience. Their immune system makes them totally unaware that there has been a virus in their body.
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Because the body is so multiply, complexly designed not to go wrong, not to experience inflammation.
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It has to be a sick and dying person to get in trouble from such a thing as a minor virus or bacteria.
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Once you're sick, then you're already in an inflamed state. And in that inflamed state, one or more viruses is just another pro-inflammatory degenerative factor.
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But a healthy person handles resistance and immunity without even noticing it.
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So the degree of inflammation that you experience with a wound or exposure to irritants and so on corresponds to your state of health.
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If one is deficient in PUFA, is it even possible to experience a significant inflammatory reaction?
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Yeah, the experiments with just rats on a PUFA-free diet, a so-called essential fatty acid-free diet, all kinds of tests, poisons, physical trauma, disease, infectious agents.
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They're just tremendously resistant to inflammation and dying.
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Something as crude as holding them by the tail and whacking them on the furniture.
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If they've been eating a standard fatty acid, PUFA-rich diet, they go into shock and inflammation and die.
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If they don't have a noticeable amount of PUFA in their tissues, they are very tough.
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I just want to see the ethical committee that approved this experiment. The description is we're going to be whacking rats on furniture.
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So basically, without PUFA, most of the inflammatory reaction is gone. Is that what I'm hearing?
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Right. The PUFA form many things leading to inflammation. Just the prostaglandins are a very powerful amplifier of inflammation.
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Some little thing like hypoglycemia can start the formation of prostaglandins. And then once it starts, all kinds of things, cytokines and circulatory changes and such get involved.
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Right. And then the leukotrienes and all the other things that are derived from PUFA?
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Yeah.
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Okay.
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Could you say something like the moment lactic acid is released out of the cell or something, that's the beginning of inflammation? Or is it much more complex than that?
00:20:03.000 --> 00:20:31.000
Yeah. A shift away from oxidation of the PUFA will inhibit the ability to oxidize glucose. And at that moment, you're experiencing reductive stress or pseudo hypoxia, some people call it.
00:20:31.000 --> 00:20:47.000
The oxygen is there, but you aren't using it. And that turns on lactic acid, which represents a reductive state, an excess of electrons.
00:20:47.000 --> 00:21:04.000
And that transmits the reductive stress wherever it goes, tends to convert other cells to that same stress state.
00:21:04.000 --> 00:21:17.000
And speaking of reductive stress and the lack of oxygen, maybe I'm getting ahead of ourselves here, but the stem cell renewal in the aspect of what you wrote about the loss of stem cells.
00:21:17.000 --> 00:21:37.000
Yeah. When you stop oxidizing glucose because of either low thyroid or some poison like nitric oxide or PUFA or carbon monoxide,
00:21:37.000 --> 00:21:50.000
the enzymes simply stop reacting glucose and its derivatives with oxygen.
00:21:50.000 --> 00:22:18.000
And so the oxygen is still diffusing in from your bloodstream, but it's not being consumed. And so the animal that is feeling its respiration is actually becoming hyperoxic in the vicinity of those poison cells.
00:22:18.000 --> 00:22:33.000
And so hyperoxia is toxic to the mitochondria and changes the functions of the stem cells.
00:22:33.000 --> 00:22:52.000
It's one of the things that brings stem cells out of their quiescent state and starts them dividing so that in an injury situation where the cell is going to die because it isn't oxidizing glucose,
00:22:52.000 --> 00:23:17.000
the stem cells can take over and replace the dead poison cell. But if the cell doesn't get out of the way, then the hyperoxia that has activated the stem cells is going to keep the multiplication going and produce a tumor.
00:23:17.000 --> 00:23:39.000
But if it is continuously in great excess, then you start depleting the stem cells and then you have no renewability of that tissue.
00:23:39.000 --> 00:23:48.000
So hyperoxia is an outcome of blocking the use of oxygen.
00:23:48.000 --> 00:24:01.000
So is carbon dioxide, the intracellular pH, is that the major signal for apoptosis of a barren cell and also the signal for the stem cells to start differentiating?
00:24:01.000 --> 00:24:06.000
The failure to produce carbon dioxide, yeah.
00:24:06.000 --> 00:24:14.000
Right, so the presence of it will allow the barren cell to commit suicide basically, to apoptosis.
00:24:14.000 --> 00:24:36.000
Yeah, its pH goes up, activating its own tendency to undergo cell division and then if there's no glucose available because it's being wasted, then that would be the normal thing that kills the cell.
00:24:36.000 --> 00:24:42.000
Is that one mechanism through which the acetylzolomide drug helps shrink the tumors?
00:24:42.000 --> 00:24:45.000
Potentially, yeah.
00:24:45.000 --> 00:25:01.000
And previously you've been asked about stem cell therapy and I don't want to misquote you, but you said something like "I think we're a big bag of stem cells" and so it's more of the environment of those stem cells than just adding a bunch more into the system?
00:25:01.000 --> 00:25:13.000
Yeah, I don't think the idea of taking them out of one place and putting them in another is going to do much, if anything.
00:25:13.000 --> 00:25:35.000
If you said that the intrauterine environment is basically the ideal environment for an organism, then by extension once the organism is being born into this world, then if we want to maintain the same level of optimal health, we should live in an environment that mimics the intrauterine one, which is with a lot of glucose and a lot of carbon dioxide. Is that right?
00:25:35.000 --> 00:25:55.000
Yeah, and on a high mountain with a supply of good fruit, for example, your oxygen tension is lower at high altitude, closer to the fetal oxygen availability.
00:25:55.000 --> 00:26:16.000
And if you're healthy enough to adapt to high altitude, then your CO2 level internally goes up and prevents the hyperventilation increase of pH inside cells that kills them or ages them.
00:26:16.000 --> 00:26:28.000
Is there an optimal range of altitude? Because clearly, just climbing up on top of Mount Everest, just to give an extreme example, that wouldn't be healthy. So it's got to be something more, I don't know, reasonable?
00:26:28.000 --> 00:26:34.000
Yeah, 8,000 to 12,000 feet I think is good.
00:26:34.000 --> 00:26:35.000
Okay.
00:26:35.000 --> 00:26:44.000
Going back a little bit on our chat about inflammation, is oxygen stress and inflammation, are those synonymous or interchangeable terms, rather?
00:26:44.000 --> 00:27:03.000
No, they usually talk about oxidative stress as making free radicals, but the thing that turns that on is often a block to the ability to use oxygen.
00:27:03.000 --> 00:27:22.000
And so the traditional use of oxidative stress has been pretty confused, defining it as just pretty much equivalent to lipid peroxidation and free radical damage.
00:27:22.000 --> 00:27:37.000
Do you know who came up with this term, oxidative stress? Because when I read the actual studies, at least the more modern versions, a lot of people are angry in those studies by saying, "Look, we're administering a drug that blocks the electron transport chain complex and creates oxidative stress."
00:27:37.000 --> 00:27:47.000
So this term is completely bogus and wrong, yet it still carries on. Somebody must have coined this cultural term and supported it throughout the years in order for it to be so powerful.
00:27:47.000 --> 00:28:07.000
Yeah, I think it goes back to Raymond Pearl and Johns Hopkins, a bunch of reductionists, basically an anti-life thing that the slower you live, the longer you live.
00:28:07.000 --> 00:28:28.000
Cooling off and being half dead, according to that view, is the way to live longer. Leonard Hayflick was in that line of thinking, just the most absurd and mechanical view of what life is.
00:28:28.000 --> 00:28:45.000
Even though he worked for a big cell culture company, he didn't have the faintest idea about how to do proper cell culture. Their goal was just to produce cells to sell them.
00:28:45.000 --> 00:29:05.000
He didn't realize that growing 50 generations in a dish is not at all comparable to the living state in an organism.
00:29:05.000 --> 00:29:26.000
People fell for that shortening telomere idea that cells necessarily, every division, shorten their telomere and have a maximum division capability of 50 cell divisions.
00:29:26.000 --> 00:29:44.000
Back in the 60s, people tested that and showed that our skin and intestine, for example, would use up those 50 cell divisions of our stem cells in just a few weeks or months.
00:29:44.000 --> 00:30:01.000
And grafting experiments found that different organs, like mammary glands, could undergo essentially an infinite number of cell divisions when they're in an organism,
00:30:01.000 --> 00:30:30.000
supporting the Rockefeller University experiments of growing chicken heart cells, keeping them alive for more than 20 years, just by renewing their environmental solution properly, not letting elastic acid accumulate.
00:30:30.000 --> 00:30:45.000
Do you think some of those ideas of the rate of living theory may have been inspired by the second law of thermodynamics and the steam presses from the England's Industrial Revolution saying, "If you keep your machines cooler, they will last longer"?
00:30:45.000 --> 00:31:05.000
Exactly. It's all mechanical thinking. And that mechanical thinking, like N. A. Kosiris, looking at the history of these physical ideas, showed that it was a belief,
00:31:05.000 --> 00:31:32.000
basically in a big bang creationist universe, that if you believe there was a creation of the universe in one moment, then you can deduce that one-directional running down of the universe.
00:31:32.000 --> 00:32:01.000
The idea of a watchmaker, a god who set the universe clock in motion, all a clock can do if God wound it up at one point is run until it loses the wind-up energy.
00:32:01.000 --> 00:32:09.000
And so the universe, from that religious viewpoint, can do nothing but run down.
00:32:09.000 --> 00:32:34.000
And N. A. Kosiris showed that if you don't make those religious assumptions, then you can explain the stellar energy source, the fact that all of the planets have an internal production of energy,
00:32:34.000 --> 00:32:48.000
even the giant gaseous planets turn out to be producing internal energy like a star developing.
00:32:48.000 --> 00:33:11.000
So I guess all these people, the religious fanatics, they observed that time passes forward, and the way they explained it was with the big bang and the unwinding of the clock, instead of the opposite, which is the Kosiris idea of the continuous creation, which is that there's more time as time goes by, because time is a property of matter.
00:33:11.000 --> 00:33:34.000
Right. And even Fred Soddy, the inventor of the isotope interpretation of atoms, even he, in one of his later books, described his thinking for continuous creation.
00:33:34.000 --> 00:33:41.000
He believed cosmic rays were the atoms just coming into existence.
00:33:41.000 --> 00:33:57.000
>> Okay. So basically time and space are essentially, both are properties of this prima mater which Aristotle talked about, the pure potential. Does that ring true?
00:33:57.000 --> 00:33:58.000
>> Yep.
00:33:59.000 --> 00:34:19.000
>> Okay. Jumping back to your newsletter, Ray, and I apologize, I know you've talked about this 100,000 million times, but the idea that tissue injury kind of invites the virus or the bacteria or the fungus, and they're not necessarily harmful in and of themselves, is that correct?
00:34:19.000 --> 00:34:25.000
And then I feel like you probably can't talk about that enough today at this time.
00:34:25.000 --> 00:34:48.000
>> Yes. And I'm in this newsletter suggesting the probability that the so-called viruses are little packets of nuclear material being exchanged throughout the world by every organism.
00:34:48.000 --> 00:34:59.000
And bacteria do it visibly, transmitting the information that they invented themselves to their friends.
00:34:59.000 --> 00:35:16.000
And every organism you look at is actually circulating exosomes, packets of information, within themselves in a repair and regenerative process.
00:35:16.000 --> 00:35:26.000
But all of their body fluids contain those same exosomes and are being released into the environment constantly.
00:35:26.000 --> 00:35:35.000
And so every organism is emitting these packets that are virus-like in structure.
00:35:35.000 --> 00:35:49.000
>> If an inflamed cell has an abundance of electrons because its metabolism is being blocked by something, could a viral or bacteria infection act as a sort of like an emergency electron sink in some fashion?
00:35:49.000 --> 00:36:02.000
>> Yeah, when the system is working well. I think that's going on all the time. You can transmit actual mitochondria in those packets.
00:36:02.000 --> 00:36:08.000
>> What kind of exosomes and what kind of things would people be emitting when they actually do take the vaccine?
00:36:08.000 --> 00:36:18.000
Like, a question I've been asked many times is, if a person gets the vaccine, are they actually more harmful to be around, do you think?
00:36:18.000 --> 00:36:45.000
>> Yeah, the purpose of the adjuvant, which had always been aluminum hydroxide, was to create systemic inflammation to stir up excitement so that your body would start making antibodies to anything novel that was present.
00:36:45.000 --> 00:37:09.000
And they talk about the lipids in these RNA vaccines as transport or mediators of cellular uptake for the RNA, but actually they're the same lipids that have been promoted for use as adjuvant.
00:37:09.000 --> 00:37:24.000
So they're just a lipid version of an adjuvant intended to create systemic inflammation big enough to get you to produce antibodies.
00:37:24.000 --> 00:37:38.000
And the antibody producing system, I don't think it's properly considered to be part of the immune system.
00:37:38.000 --> 00:37:57.000
The whole process should be maintenance of our structural functional system, and the antibodies are part of a cleanup system.
00:37:57.000 --> 00:38:12.000
You have, for example, natural killer cells that will remove damaged cells, killing them so the parts can be removed.
00:38:12.000 --> 00:38:37.000
And when you have a tissue that isn't quite ready to have the natural killer cells destroy the damaged substance, you have antibodies that are helping to mop up and control and prepare,
00:38:37.000 --> 00:38:53.000
clean up the area so that phagocytes can remove the debris and restore some of the cells to normal functioning without having to kill them.
00:38:53.000 --> 00:39:00.000
So if somebody was vaccinated, would that be risky to be around them?
00:39:00.000 --> 00:39:09.000
Being around sick people, inflamed people, I think always has more risk.
00:39:09.000 --> 00:39:18.000
In the winter, people going indoors, staying indoors, and breathing the same air.
00:39:18.000 --> 00:39:43.000
Once one person is under stress, they're going to be putting out more exosomes, and if their exosomes happen to be coming out of stressed cells rather than the normal low oxygen stem cell sources,
00:39:43.000 --> 00:39:50.000
then their exosomes can be irritating and spread through inflammation.
00:39:50.000 --> 00:40:07.000
Do you think that might explain why nurses working in specific hospital wards, in general medical personnel that spend a lot of time with those sick people, tend to come down with similar conditions if they spend years in those same wards?
00:40:07.000 --> 00:40:09.000
I think so.
00:40:09.000 --> 00:40:15.000
And you described maybe a person being around you, but what happens when a population is like it?
00:40:15.000 --> 00:40:27.000
I guess we're already in a sick population, so can it be that much worse if everybody is vaccinated and, I don't know, spreading and exchanging with these inflammatory materials?
00:40:27.000 --> 00:40:38.000
I think everything the medical system is doing tends to degrade the whole population a little.
00:40:38.000 --> 00:40:56.000
Speaking of degrading the whole population, so Ray, somebody you've mentioned on previous shows was Mike Yudon, who is a former Pfizer VP and Chief Science Officer, and a topic that you and I, I think, first talked about this in 2017, and I know you've been studying it for a lot longer than that, but he said,
00:40:56.000 --> 00:41:14.000
"It's my considerate view that it's entirely possible that coronavirus vaccines will be used for massive-scale depopulation." And so given your insights of how these things are formulated or how they're said to be formulated, do you think he might be onto something there?
00:41:14.000 --> 00:41:39.000
Oh yeah, the possibility is there, and when you look at the lying, deliberate breaking of the law of high government officials, World Health Organization, CDC, and the top levels of foundations like the Gates Foundation,
00:41:39.000 --> 00:42:01.000
you see them deliberately misleading the population. I think it's odd to assume that they wouldn't be trying to execute what they've expressed as their long-range goals, population reduction,
00:42:01.000 --> 00:42:29.000
since they have the means now, and since they've demonstrated that they're morally corrupt, and basically profiting from misleading the public to assume that they're not criminal on multiple levels, I think would be a mistake.
00:42:29.000 --> 00:42:42.000
And this is something we've talked about. This is like a, I'm using air quotes right here, but an open conspiracy. It's like the culture of the Pentagon and the CIA and the WEF and WHO and CDC, all these institutions.
00:42:42.000 --> 00:43:03.000
It's like depopulation isn't a radical idea. It's just kind of the status quo, and it's not an insane idea among the people that populate these institutions, but when you talk to somebody off the street, "Oh, they want to depopulate," it's like, "What? No, that's impossible. How can they do that?"
00:43:03.000 --> 00:43:13.000
There's so many immediate objections to that, but what we've talked about before, it's not controversial at all among those people that I just mentioned.
00:43:13.000 --> 00:43:27.000
>> Yeah, and that attitude is exactly what you need to keep them as not believing that it's possible while it's going on.
00:43:27.000 --> 00:43:40.000
Didn't Kissinger state as far back as the '70s that basically there can be only one destiny for the third world, and that is extermination at the hands of the powers that be, of the Western powers?
00:43:40.000 --> 00:44:09.000
>> Yeah, I think that policy was basically decided when Roosevelt died. Roosevelt and Wendell Willkie had a meeting and decided on a post-war policy of bringing the third world up to the rest of society.
00:44:09.000 --> 00:44:15.000
Making them independent and affluent and prosperous.
00:44:15.000 --> 00:44:30.000
Right after the meeting, Willkie died unexpectedly of a cold.
00:44:30.000 --> 00:44:48.000
Within just a few days of the revelation that Dulles and the whole organization were working with the Nazis, Roosevelt died in a very timely way.
00:44:48.000 --> 00:45:08.000
And immediately the policies towards the third world changed radically from giving the equivalent of a Marshall Plan to bring up all of the third world countries to a good standard of living.
00:45:08.000 --> 00:45:15.000
That immediately changed back to the empire of exploiting them to death.
00:45:15.000 --> 00:45:27.000
>> Stalin saw what happened to Roosevelt, didn't buy for a second what the official story was, and would that explain why the Soviet Union became much more hard-line afterwards? He realized what he's up against?
00:45:27.000 --> 00:45:41.000
>> Yeah, and even some of Roosevelt's relatives agreed with Stalin that it was an assassination.
00:45:41.000 --> 00:45:51.000
>> Speaking of assassination, Ray, do you want to comment on John Magu Fuli and the very likelihood that he was killed in some way?
00:45:51.000 --> 00:46:03.000
>> He was the second African president who had opposed vaccinations who died suddenly.
00:46:03.000 --> 00:46:07.000
>> The first one was Mugabe, the Zimbabwean? Or no?
00:46:07.000 --> 00:46:21.000
>> I forget the previous one, just a few months before, but they were both very antagonistic to the World Health Organization and the vaccine campaigns.
00:46:21.000 --> 00:46:28.000
>> Because African Americans are woke to Western medical intervention, you think?
00:46:28.000 --> 00:46:37.000
>> Probably more than other countries because they've had more horrible experiences.
00:46:37.000 --> 00:46:58.000
>> This is mind-blowing to me, but to you, this has been happening forever. These very critical people of the establishment just passing away instantaneously, and I doubt there's going to be any BLM marches or anything about the death of Magu Fuli.
00:46:58.000 --> 00:47:05.000
>> No, I haven't heard very much public discussion of it.
00:47:05.000 --> 00:47:19.000
>> We'll continue this chat. Let me do an advertisement here really quickly. We're discussing Ray's newsletter, which is available by email now. It's $28 U.S., and you can send that to rayPeats@gmail.com.
00:47:19.000 --> 00:47:30.000
You can also order books by Ray, his "Gender of Energy" book, "1994 from PMS to Menopause." When was that written, Ray?
00:47:30.000 --> 00:47:36.000
>> In the early '80s, I think it was.
00:47:36.000 --> 00:47:44.000
>> '80s, and then "Nutrition for Women," 1973, and then "Mind and Tissue 2." When was that written?
00:47:44.000 --> 00:47:52.000
>> 1973 was when I wrote "Mind and Tissue" a little before "Nutrition for Women," I think.
00:47:52.000 --> 00:47:59.000
>> Okay, so you can send that email address and the name of the book, and I still have the wrong prices on here, so they should be cheaper.
00:47:59.000 --> 00:48:13.000
And then, like last time, I just wanted to mention Progest-E from Kenogen, and you can email Catherine at Kenogen@gmail.com, and each bottle is 3,400 milligrams of progesterone.
00:48:13.000 --> 00:48:19.000
And Ray, just want to maybe comment on your thoughts on Progest-E.
00:48:19.000 --> 00:48:42.000
>> More men are starting to use it, and you've probably heard the result of the injecting, I think it was micronized progesterone subcutaneously in men who were infected seriously with COVID.
00:48:42.000 --> 00:48:44.000
>> Yeah, yeah, we talked about it a little bit last time.
00:48:44.000 --> 00:49:00.000
>> A study ended and was published finally that it did improve their survival, so that is increasing the interest of men in using it.
00:49:00.000 --> 00:49:18.000
I had probably discouraged men for a long time when I described how a big dose of it is like a cold shower and shrinks the penis, but that effect passes in about one or two days.
00:49:18.000 --> 00:49:32.000
So, with the proper dosing, it actually increases libido and keeps testosterone from being wasted and turned into estrogen.
00:49:32.000 --> 00:49:38.000
So, it's actually a very important part of the male system.
00:49:38.000 --> 00:49:40.000
>> I'm actually glad you brought that up.
00:49:40.000 --> 00:49:44.000
So, we have a large 20s, 30s, 40s male listenership.
00:49:44.000 --> 00:49:49.000
So, one, how much progesterone does a healthy male make?
00:49:49.000 --> 00:50:01.000
And then, I know this is extremely individual, but is there any way to go about dosing progesterone for a male, and what should they expect when they use it?
00:50:01.000 --> 00:50:14.000
>> The basic mechanism is that it promotes, a given dose promotes its own synthesis in the body,
00:50:14.000 --> 00:50:29.000
and partly that's because it facilitates the secretion of thyroid hormone, which is part of the conversion of cholesterol to progesterone.
00:50:29.000 --> 00:50:40.000
And partly because it inhibits the enzyme aromatase that converts androgens to estrogen.
00:50:40.000 --> 00:51:01.000
And it supports the internal system of getting the vitamin A and thyroid together with the cholesterol, so that often during pregnancy,
00:51:01.000 --> 00:51:20.000
if a woman is seriously deficient in progesterone, one single big dose will sometimes set the pregnancy back on the normal course of producing progesterone at an increasing rate for the full nine months.
00:51:20.000 --> 00:51:43.000
Sometimes it takes two injections, but the principle is that when you get the right amount at one moment, your thyroid and gonads and skin and brain, everything gets back on the track to produce enough of your own progesterone.
00:51:43.000 --> 00:51:53.000
So it isn't a hormone replacement matter, but it's a stress correction process.
00:51:53.000 --> 00:52:03.000
You stop the stress, and if you're well nourished, the organism gets back to its production.
00:52:03.000 --> 00:52:18.000
I have a question. I get a lot of questions from parents who are considering using Progest-E in children. Do you have any reservations, misgivings about giving little children progesterone, in Progest-E specifically?
00:52:18.000 --> 00:52:41.000
Very premature babies, their brain growth is protected, sort of like imitating intrauterine conditions, to give them a little progesterone for the first few months of their life to keep the brain developing.
00:52:41.000 --> 00:53:04.000
That probably can be beneficial if there has been stress so that they had some deficiency of progesterone that could be continued right up through all of the time breastfeeding is going on.
00:53:04.000 --> 00:53:17.000
If the mother normalizes her progesterone, the progesterone level of the milk will be adequate, and that will help the baby's brain develop.
00:53:17.000 --> 00:53:43.000
But if you give it to a boy just as their puberty is coming on, you potentially, by giving too much for too long, you could delay their development sexually probably.
00:53:43.000 --> 00:53:58.000
I don't know if that's ever happening, but I think it's good to think of it as a restorative starting up support rather than a continuing maintenance.
00:53:58.000 --> 00:54:08.000
The specific question I'm getting is that a lot of parents are concerned that during the pregnancy the mother was under stress, received vaccines, was working really hard.
00:54:08.000 --> 00:54:16.000
So basically they're saying now their children that are born and becoming three, four, five years old, they're seeing some signs that are indicative of a stress imprint.
00:54:16.000 --> 00:54:24.000
Like the child is gaining weight, and while the parents are normal weight, the child is having food allergies while the parents don't have them.
00:54:24.000 --> 00:54:31.000
Some of them have had really good success with progest-E, and they keep asking me questions.
00:54:31.000 --> 00:54:47.000
Are there any concerns about using progest-E sporadically on a child that's small, aside from delaying puberty? Would there be a problem in terms of somehow disbalancing their hormonal status if it's used for a few months or so?
00:54:47.000 --> 00:55:08.000
No. It's possible to suppress the formation of testosterone if you take really big doses, but when you do it by symptoms, five or ten milligrams a day can alleviate symptoms.
00:55:08.000 --> 00:55:17.000
Sometimes one dose of 20 milligrams can just cure the problem. It doesn't have to be repeated.
00:55:17.000 --> 00:55:35.000
But you should always go by watching the effects of it because they are very obvious when you're having progesterone deficiency symptoms, very similar to low T3 symptoms.
00:55:35.000 --> 00:55:44.000
You should see the results happening within five or ten minutes or at most an hour.
00:55:44.000 --> 00:55:54.000
So you can take a drop or two, wait ten or fifteen minutes, and if you still have the symptoms, then you can repeat it.
00:55:54.000 --> 00:56:06.000
How much progesterone daily do you think a healthy child is producing at that age, like before the teens, like a child up to ten years of age, male or female?
00:56:06.000 --> 00:56:13.000
Probably somewhere between ten and thirty milligrams.
00:56:13.000 --> 00:56:21.000
So that would be essentially, up to that would be a good replacement dosage if the parent thinks there's an issue and they want to try it?
00:56:21.000 --> 00:56:38.000
Yeah, the thirty milligrams is a very strong dose. That's the dose that can temporarily shrink a man's penis by blocking testosterone.
00:56:38.000 --> 00:56:51.000
But five or ten milligrams is usually a very adequate corrective anti-stress dose.
00:56:51.000 --> 00:56:57.000
But for a little girl, those concerns are not present, right? It shouldn't be an issue?
00:56:57.000 --> 00:57:08.000
No, I just don't think the larger amounts are necessary because it stimulates its own corrective production.
00:57:08.000 --> 00:57:15.000
For a hypothyroid child at that age, do you think progesterone would be safer to try first than jumping directly on thyroid?
00:57:15.000 --> 00:57:39.000
No, usually I think it's good to use a small amount of thyroid as if you're eating a traditional diet, eating boiled whole fish or soup made out of all the parts of a chicken or whatever.
00:57:39.000 --> 00:57:51.000
That would be giving you maybe a fourth to a half a grain of thyroid every day just as part of your meat diet.
00:57:51.000 --> 00:58:04.000
Really, that small amount of thyroid should just be a standard part of nutrition.
00:58:04.000 --> 00:58:27.000
The government in the early 1940s required the meat producers to remove the thyroid, setting up a situation in which our diet is pretty free of the natural amount of thyroid unless you drink a large amount of milk.
00:58:27.000 --> 00:58:34.000
Even cow's milk contains a moderate helpful amount of thyroid hormone.
00:58:34.000 --> 00:58:38.000
What about fish head soup? They're not removing the thyroid from that, right?
00:58:38.000 --> 00:58:47.000
Right, right. If you have a fish market, that will include the heads.
00:58:47.000 --> 00:58:57.000
I've been receiving more and more people saying they have wild experiences with Sinoplus.
00:58:57.000 --> 00:59:05.000
If somebody did feel like that, would you say to try a higher ratio of T3 to T4?
00:59:05.000 --> 00:59:09.000
Would you suggest aspirin? Would you suggest progesterone?
00:59:09.000 --> 00:59:19.000
Maybe if they were interpreting the symptoms correctly, it being liver related, is that something that you receive messages about?
00:59:19.000 --> 00:59:46.000
Yeah, usually the problem is that they don't go at it gradually enough. It should increase gradually over a period of two or three months, steadily increasing, watching your temperature and pulse rate and adjusting the dose according to those.
00:59:46.000 --> 01:00:01.000
If you jump right in with what you think is going to be your dose, that's when you're more susceptible to building up too much T4.
01:00:01.000 --> 01:00:15.000
What about, so as we go through time here and as people get progressively sicker and sicker, would you see an issue, more and more of an issue with a one to four ratio as people get sicker and sicker?
01:00:15.000 --> 01:00:29.000
I've known many people who benefited from going up to about a one to two ratio,
01:00:29.000 --> 01:00:49.000
having that little bit of T4 to help hold down their TSH during the night when the TSH contributes to the stress experience.
01:00:49.000 --> 01:01:09.000
The bedtime T4 will minimize that and still they're getting a good amount of T3, enough that that will keep their blood sugar up so that they don't fail to convert to T4.
01:01:09.000 --> 01:01:19.000
Great stuff. Man, I just had a blank. I wanted to ask you one other question about this. Oh, I remember I was going to say, I have been saying this wrong for 10 years.
01:01:19.000 --> 01:01:30.000
And you have mentioned it many times, I think because when I go to the Armour website and I'd read what a grain was, it was about like nine micrograms of T3, maybe 38 micrograms of T4.
01:01:30.000 --> 01:01:42.000
And so I always thought that was a grain, but now I understand that a sinoplus is about, and correct me if I'm wrong, but 12.5 micrograms of T3 and maybe 50 micrograms of T4.
01:01:42.000 --> 01:01:47.000
And then a fourth of a sinoplus is about a half, a little more than half a grain. Is that right?
01:01:47.000 --> 01:02:04.000
Close to that, yeah. And the original Armour thyroid, the ratio in one publication was close to three to one rather than four to one.
01:02:04.000 --> 01:02:23.000
And they didn't talk about the amount of T4 or T3. They apparently had done it without even knowing the existence of T3 and T2 for so long.
01:02:23.000 --> 01:02:42.000
They were relying on testing the biological effects on mice. Every batch they would mix up thyroids from different cows or pigs, whichever it was, and they produced both.
01:02:42.000 --> 01:03:01.000
You could buy beef or pork thyroid from Armour and each of them was batch standardized to give a reliable physiological effect on mice.
01:03:01.000 --> 01:03:29.000
So they didn't care what the T4 and T3 content was. It was the biological effect. They were defining their grains and they would dilute it accordingly with, I think, lactose and stearic acid or magnesium stearate to glue the tablets together.
01:03:29.000 --> 01:03:39.000
- Great stuff, George, if you didn't have a question, maybe we'll take a user, or why do I keep saying a user question? Like a watcher, listener question? Okay, well, let me play this one.
01:03:39.000 --> 01:03:46.000
Let me know if you can hear this right. This one's from Sheila and it's about children and school.
01:03:46.000 --> 01:03:49.000
- Hey, Dr. Peat. - You can hear that right, right?
01:03:49.000 --> 01:03:52.000
- Yep. - Okay.
01:03:52.000 --> 01:04:06.000
- Hey, Dr. Peat, this is Sheila. I have a middle school daughter who is remote learning for about a year now due to lockdown restrictions.
01:04:06.000 --> 01:04:20.000
And she is understandably failing behaviorally and academically. Good grades, but just we're seeing her fade away.
01:04:20.000 --> 01:04:46.000
And my concern is, for me moving forward, trusting what our state offers us and our district offers us academically and how they're going about teaching and then in the future, just investing in colleges.
01:04:46.000 --> 01:05:05.000
And I guess what I'm asking is, how do I align my expectations with the reality of what the future is going to look like educationally for these children? Thank you.
01:05:05.000 --> 01:05:26.000
I think the thing is to work on trying to get the alignment back to the human concept of what education is via a computer.
01:05:26.000 --> 01:05:44.000
Not only a standardized curriculum, but standardized methods and format. Everything is being standardized out of normal human reality.
01:05:44.000 --> 01:06:04.000
That just doesn't work in the long run. If you accept it, then I think you're strengthening an irrational system.
01:06:04.000 --> 01:06:17.000
I think everyone has to start rejecting digital education, artificial intelligence, as well as standardized curricula.