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kmud-160219-iodine-supplement-reactions-hormones.vtt
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WEBVTT
00:00:00.000 --> 00:00:26.500
[Music]
00:00:26.500 --> 00:00:30.900
Welcome to Ask Your Herb Doctor. My name is Andrew Murray. My name is Sarah
00:00:30.900 --> 00:00:34.580
Johanneson Murray. We both trained in England and graduated there with a
00:00:34.580 --> 00:00:38.220
degree in herbal medicine and clients consult with us regarding their health
00:00:38.220 --> 00:00:42.300
issues and we recommend personalized advice in nutrition, supplements, herbs,
00:00:42.300 --> 00:00:48.880
diet, lifestyle. We can be reached toll-free at 1-888-WBM-HERB or on the
00:00:48.880 --> 00:00:56.180
web at www.westernbotanicalmedicine.com. So on tonight's show we're very welcome
00:00:56.180 --> 00:01:00.700
again to have Dr. Raymond Peat joining us to give us the answers to his wisdom,
00:01:00.700 --> 00:01:05.700
from his wisdom, explaining those things that perhaps not what we normally would
00:01:05.700 --> 00:01:09.620
hear in the mainstream, almost certainly not what we would hear in the mainstream,
00:01:09.620 --> 00:01:15.340
but nonetheless very well researched, plenty of information there that people
00:01:15.340 --> 00:01:21.820
can also look at after the show either by visiting Dr. Peat's website at
00:01:21.820 --> 00:01:27.580
www.raypeat.com. Plenty of articles fully referenced and like I said most of the
00:01:27.580 --> 00:01:31.900
subjects there will have advice and research that you probably would not
00:01:31.900 --> 00:01:34.800
have heard of elsewhere. So we're always very pleased to have Dr. Peat on the
00:01:34.800 --> 00:01:40.460
show. Thanks for your time Dr. Peat. For people who perhaps have never heard you
00:01:40.460 --> 00:01:45.740
or listened to the show, would you give people your background, your academic
00:01:45.740 --> 00:01:50.740
and professional background before we get into the subject? After getting
00:01:50.740 --> 00:01:58.180
a master's degree in humanities at University of Oregon, I came back in 1968
00:01:58.180 --> 00:02:09.220
to 72 for a biology PhD concentrating on reproductive physiology. The
00:02:09.220 --> 00:02:17.460
hormones involved in reproduction are involved in everything relating to life
00:02:17.460 --> 00:02:27.700
and brain development was one of my second themes of research. So brain
00:02:27.700 --> 00:02:32.700
development, aging and the hormones involved in that gradual decline
00:02:32.700 --> 00:02:37.460
in good health. Okay so just for people that are listening to the show that we
00:02:37.460 --> 00:02:42.100
will be taking calls from 7.30 till the end of the show either related to this
00:02:42.100 --> 00:02:45.980
month's continuing topic of nitric
00:02:45.980 --> 00:02:51.740
oxide. I wanted to get a little bit into the subject of iodine as an opener for
00:02:51.740 --> 00:02:56.740
the show for people thinking about supplementing with iodine and also open
00:02:56.740 --> 00:03:00.540
up a little bit about the Zika virus that's really catching media attention
00:03:00.540 --> 00:03:08.740
here. I know there's certain, what do you want to say, authoritative reasons for it and
00:03:08.740 --> 00:03:12.220
there are other supposedly conspiracy theories that we can call them
00:03:12.220 --> 00:03:16.020
conspiracies but I think some of the merits of the conspiracies are worth
00:03:16.020 --> 00:03:21.060
picking up and exploring. Anyway so if you live here in the area
00:03:21.060 --> 00:03:29.940
the number is 1-800-KMUD-RAD or 923-3911. Again that 800 number, we do get
00:03:29.940 --> 00:03:33.020
people from all over the States calling so that 800 number, let me just spell
00:03:33.020 --> 00:03:42.940
that out for you, that's 1-800-568-3723. So Dr. Peat I was looking today and I
00:03:42.940 --> 00:03:50.740
guess what's prompted it really is hearing the advice of people touting a
00:03:50.740 --> 00:03:55.900
product called nascent iodine and I know that you specialize in thyroid hormone
00:03:55.900 --> 00:04:03.340
and that iodine is definitely a key component of thyroid hormone and I think
00:04:03.340 --> 00:04:06.620
we've always been led to believe that there has been an adequate supply of
00:04:06.620 --> 00:04:13.340
iodine in the diet and then they produce iodized salt back in the 50s or 60s
00:04:13.340 --> 00:04:18.980
perhaps earlier or not I'm not too sure but iodized salt has been around and
00:04:18.980 --> 00:04:23.340
seafood also contains a lot of iodine in its own right so when I heard about this
00:04:23.340 --> 00:04:31.140
product called nascent iodine they were saying that it was essentially not the
00:04:31.140 --> 00:04:39.140
stable so stable ionic form and was more available was more readily taken up by
00:04:39.140 --> 00:04:43.500
the thyroid gland and then I read some other articles about nascent iodine and
00:04:43.500 --> 00:04:49.400
how reactive it was and I just wanted to feel you out what you what you know
00:04:49.400 --> 00:04:54.180
about the thyroid's natural need for iodine whether or not we are deficient
00:04:54.180 --> 00:04:57.500
and whether or not we need supplementation and if in fact this is
00:04:57.500 --> 00:05:04.700
something actually that may not be necessary. In the 1980s I was looking
00:05:04.700 --> 00:05:11.340
into the iodine nutrition question because I saw some women with breast
00:05:11.340 --> 00:05:19.040
disease who recovered quickly when they took supplements of kelp or thyroid
00:05:19.040 --> 00:05:25.580
hormone and the safest thing I think it is to correct the thyroid
00:05:25.580 --> 00:05:34.380
problem directly rather than counting on big doses of iodine because the large
00:05:34.380 --> 00:05:43.780
doses over many years for example there are about 70 or more publications
00:05:43.780 --> 00:05:50.860
looking at iodine intake around the world over a period of decades and they
00:05:50.860 --> 00:05:58.860
see that over half a milligram or even especially over one milligram of iodine
00:05:58.860 --> 00:06:05.860
per day over a population is closely connected with increased risk of
00:06:05.860 --> 00:06:16.100
thyroiditis and thyroid cancer. Wow, so it's aggravatory. One of the theories of
00:06:16.100 --> 00:06:23.820
why that happens is that iodine spontaneously reacts or in the presence
00:06:23.820 --> 00:06:30.620
of white blood cells their enzymes can cause iodine to react with fatty acids
00:06:30.620 --> 00:06:39.140
that are unsaturated and if you've heard about the iodine number to describe the
00:06:39.140 --> 00:06:49.260
degree of unsaturation of a fat for example the food oils that are highly
00:06:49.260 --> 00:06:56.260
unsaturated have a high iodine number that means the number of molecules of
00:06:56.260 --> 00:07:03.940
iodine that will be spontaneously absorbed by a certain quantity of the
00:07:03.940 --> 00:07:14.060
oil because the iodine attacks the double bonds in the fat and where they
00:07:14.060 --> 00:07:22.020
lack hydrogen saturation the iodine fills in analog saturated hydrogen
00:07:22.020 --> 00:07:29.380
content so there is this tendency of unsaturated fats to react with iodine
00:07:29.380 --> 00:07:36.020
and when that happens the body can interpret that as a signal to the
00:07:36.020 --> 00:07:43.100
thyroid gland possibly imitating the thyroid stimulating hormone. Really? Wow.
00:07:43.100 --> 00:07:47.940
So it doesn't cause an increase of thyroid hormone?
00:07:47.940 --> 00:07:57.140
It can fill the site where thyroid stimulating hormone should be
00:07:57.140 --> 00:08:04.380
acting and it can interfere with that so it probably can go either way forcing
00:08:04.380 --> 00:08:13.340
too much activity or more likely blocking the effect of TSH. The
00:08:13.340 --> 00:08:20.380
polyunsaturated fats by themselves interfere with the enzyme which releases
00:08:20.380 --> 00:08:26.420
thyroid hormone from the gland so too much of the unsaturated fats with or
00:08:26.420 --> 00:08:33.220
without iodine will have an anti thyroid effect but potentially the iodine
00:08:33.220 --> 00:08:42.260
reaction could cause overstimulation by thyroid stimulating hormone or in its
00:08:42.260 --> 00:08:48.340
place could imitate the action. But you mentioned the the binding the iodine
00:08:48.340 --> 00:08:55.180
binding to the double bonds producing this product and in its own right that
00:08:55.180 --> 00:09:02.860
could stimulate a inflammatory thyroiditis and/or a cancer? Yeah I think
00:09:02.860 --> 00:09:09.340
that's why the the high iodine intake around the world statistically is
00:09:09.340 --> 00:09:15.900
associated with greater risk of thyroid cancer and if there really were a
00:09:15.900 --> 00:09:22.220
product that contained a more reactive form of iodine that would just mean that
00:09:22.220 --> 00:09:30.500
it would attack more molecules but I looked up the source of that product of
00:09:30.500 --> 00:09:38.100
one of the products started about 10 years ago and in Texas filed a patent
00:09:38.100 --> 00:09:44.540
that is just completely goofy if you look at the diagram okay it shows
00:09:44.540 --> 00:09:50.300
things that just can't happen right so it was filed 10 years ago and I think
00:09:50.300 --> 00:09:57.020
it still hasn't been and probably never will be actually approved as a patent so
00:09:57.020 --> 00:10:03.260
it you can apply for a patent on any goofy idea and then publish the
00:10:03.260 --> 00:10:08.660
application and impress a lot of people. But maybe not bear the bring the product
00:10:08.660 --> 00:10:16.420
to the market. So iodine supplementation is is very risky and basically you
00:10:16.420 --> 00:10:21.100
should get your trace minerals from seafood sources rather than from
00:10:21.100 --> 00:10:24.980
isolated iodine supplements and especially not in combination with any
00:10:24.980 --> 00:10:30.900
kind of vegetable polyunsaturated oils? Yeah I think that's true. So just to
00:10:30.900 --> 00:10:35.100
quickly wrap up this nascent iodine I think the reason that it caught my
00:10:35.100 --> 00:10:41.060
attention was that the media spin on it was that because it didn't have a and in
00:10:41.060 --> 00:10:43.460
chemistry people hearing this will understand what I'm saying but it's
00:10:43.460 --> 00:10:47.500
probably I can go and elaborate it more simply perhaps but it doesn't have a
00:10:47.500 --> 00:10:52.340
stable octet so it's out of electron shell isn't filled and they were saying
00:10:52.340 --> 00:10:58.500
that because of this it was much more much more suitable in some way to
00:10:58.500 --> 00:11:04.780
occupying these sites in the thyroid to produce thyroid hormone but it's very
00:11:04.780 --> 00:11:09.300
reactivity is counterproductive because surely as soon as you if you could keep
00:11:09.300 --> 00:11:12.500
it as unreactive as that in a bottle waiting to be ingested wouldn't it
00:11:12.500 --> 00:11:15.940
surely and react with one of the first things that came into contact with when
00:11:15.940 --> 00:11:22.500
you ingested it just to fill its octet and become stable again? Oh yeah the whole
00:11:22.500 --> 00:11:29.940
idea of newly born or a nascent molecule when I was in junior high and high
00:11:29.940 --> 00:11:35.980
school the chemistry people talked about nascent oxygen which for a few seconds
00:11:35.980 --> 00:11:40.860
after it's formed in a certain way is highly reactive but that's because the
00:11:40.860 --> 00:11:47.300
electrons are simply in an excited state like it had been sitting in in the
00:11:47.300 --> 00:11:55.140
sunlight too long that's an electronic excitation which quickly passes as it
00:11:55.140 --> 00:12:04.900
gives off a little bit of energy but in in certain short-term situations of a
00:12:04.900 --> 00:12:10.900
few seconds that kind of excited electron state can make a molecule
00:12:10.900 --> 00:12:16.100
useful for certain reactions but isn't something you'd want to put in your body
00:12:16.100 --> 00:12:22.340
yeah okay so not for in vivo use but maybe in in vitro experimentations it
00:12:22.340 --> 00:12:27.660
might have a some kind of a use. So it's basically a more dangerous form of
00:12:27.660 --> 00:12:33.020
iodine that can cause a free radical reaction? Yeah that's what they're
00:12:33.020 --> 00:12:38.500
talking about but I don't think it even exists in the product. Got it okay well
00:12:38.500 --> 00:12:43.460
you're listening to AskUrbDr and Kami DeGalbaville 91.1 FM from 730
00:12:43.460 --> 00:12:47.380
to the end of the show. Callers are invited to call in with any questions
00:12:47.380 --> 00:12:52.540
about this month's wide topic here of things like obviously thyroid hormone is
00:12:52.540 --> 00:12:55.260
going to interplay in a lot of it but the nascent iodine that we've just
00:12:55.260 --> 00:12:59.300
brought up here and then the inflammatory reactions that happen
00:12:59.300 --> 00:13:04.620
between estrogen and nitric oxide and what we can do what females as well as
00:13:04.620 --> 00:13:09.300
males can do to offset their burden. Number here if you live in the area is
00:13:09.300 --> 00:13:13.620
923 3911 if you want an 800 number for toll-free for across the states here
00:13:13.620 --> 00:13:24.180
it's 1-800-568-3723 that translates as 1-800-KMUD-RAD. So Dr. Peat I was
00:13:24.180 --> 00:13:29.500
looking at some abstracts here that we're going to form the show and the
00:13:29.500 --> 00:13:33.660
first couple caught my attention just because they were based on isoflavones
00:13:33.660 --> 00:13:41.340
and I know from our studying herbal medicine soy and isoflavones were all
00:13:41.340 --> 00:13:47.860
the rage and were touted as being very health beneficial reducing cholesterol
00:13:47.860 --> 00:13:52.900
and all this other ridiculously unscientific information that was
00:13:52.900 --> 00:13:58.780
purported. So from the basis of soy they mentioned that there was
00:13:58.780 --> 00:14:08.140
an alcohol soluble fraction that had been shown essentially to basically
00:14:08.140 --> 00:14:15.740
cause female cancers that these things were taken up by the thyroid or they
00:14:15.740 --> 00:14:21.540
probably inhibited the uptake of iodide from in by the thyroid by the gland and
00:14:21.540 --> 00:14:28.700
that this increased the estradiol in females and that this was I know that
00:14:28.700 --> 00:14:33.340
we've heard about soy and now I know we're definitely aware of soy being very
00:14:33.340 --> 00:14:39.300
pro-carcinogenic because it's a estrogen mimic. But what do you what do you think
00:14:39.300 --> 00:14:43.700
about this whole industry push that was producing and probably still is
00:14:43.700 --> 00:14:49.660
producing soy infant formula which is one of the main one of the main foods
00:14:49.660 --> 00:14:57.100
that was generated from it. I think it has seriously harmed lots of kids by
00:14:57.100 --> 00:15:05.740
partly the estrogenic effect. The oil itself has a pro-estrogen effect
00:15:05.740 --> 00:15:14.900
anti-thyroid effect apart from the those little molecules the isoflavones. The
00:15:14.900 --> 00:15:23.820
category of flavones or flavonoids it's very similar to the isoflavones. The
00:15:23.820 --> 00:15:33.100
phenyl group or benzene group is just located slightly closer to the keto
00:15:33.100 --> 00:15:40.460
oxygen in the isoflavones and that group seems to be the estrogenic group. The
00:15:40.460 --> 00:15:46.740
other orientation of the benzene group makes it more likely to be anti
00:15:46.740 --> 00:15:53.660
estrogenic and lots of fruits and vegetables contain the anti-estrogenic
00:15:53.660 --> 00:16:02.980
forms of those but the estrogen industry as a background led to a lot of the
00:16:02.980 --> 00:16:11.980
sales talk about the effects of soy chemicals. And of course is a hugely
00:16:11.980 --> 00:16:19.060
cultivated GMO cultivated product with patents owned for its for its
00:16:19.060 --> 00:16:24.500
propagation and its use. Again no doubt another spawned product from big
00:16:24.500 --> 00:16:30.260
corporations who essentially want to own the product. But don't all legumes have
00:16:30.260 --> 00:16:35.940
these a certain percentage of these isoflavones? Yeah. But just soy is
00:16:35.940 --> 00:16:43.260
particularly high? No I think the main problem with soy besides it being
00:16:43.260 --> 00:16:52.780
basically inedible I think the main problem is that it's almost all grown in
00:16:52.780 --> 00:16:59.580
the genetically modified form that takes large amounts of toxic pesticides. Which
00:16:59.580 --> 00:17:04.860
are estrogenic too right? Yeah. And again just for the guys out there I think it's
00:17:04.860 --> 00:17:09.660
very important to make you aware that you know guys have estrogen. It's not
00:17:09.660 --> 00:17:16.620
just a female dominated situation and soy consumption in males has also been
00:17:16.620 --> 00:17:21.980
positively associated with things like gynecomastia which is another side
00:17:21.980 --> 00:17:26.980
effect if you like of estrogen activity within males. The very same thing Dr. B
00:17:26.980 --> 00:17:32.020
also isn't it with alcohol drinking alcohol excess excessively can produce
00:17:32.020 --> 00:17:38.420
a symptom of male breasts so that's a estrogen type reaction. When I was a kid
00:17:38.420 --> 00:17:47.940
just before the Second World War we knew some of the very poor immigrants to
00:17:47.940 --> 00:17:54.620
California and there was one couple in which the wife got a job but the father
00:17:54.620 --> 00:17:59.580
could nurse the baby because his estrogen had become so high for
00:17:59.580 --> 00:18:05.580
malnutrition and at the end of the Second World War when soldiers got out
00:18:05.580 --> 00:18:11.040
of the prison camps lots of them had breasts from the effects of prolonged
00:18:11.040 --> 00:18:17.980
starvation. Are we talking lactation too? Well in the case of this man in
00:18:17.980 --> 00:18:27.460
California the wife said pause milk ain't got much strength. Yeah they can
00:18:27.460 --> 00:18:33.940
lactate if they have a baby nursing. Wow so there's enough positive
00:18:33.940 --> 00:18:39.100
feedback in the physiological mechanism there inherently to to produce that. So I
00:18:39.100 --> 00:18:43.780
guess the high estrogen then stimulated raised their prolactin? Yeah. And then
00:18:43.780 --> 00:18:47.820
with the suckling it produced milk? Yeah. That is just absolutely
00:18:47.820 --> 00:18:53.420
incredible. Okay so again just for people that are listening it just begs the
00:18:53.420 --> 00:19:00.060
question again where things like soy and soy products all we ever hear we don't
00:19:00.060 --> 00:19:03.380
have a television really or listen we don't have a TV at all but we don't
00:19:03.380 --> 00:19:07.580
listen to either you know broadcasts from mainstream media but what I was
00:19:07.580 --> 00:19:10.660
going to say was most people have a TV or they're listening to a regular radio
00:19:10.660 --> 00:19:15.260
station getting the same spin put on things and the same sales pitch and so
00:19:15.260 --> 00:19:20.100
I'm just find it hard to believe that for a long time the whole soy thing
00:19:20.100 --> 00:19:24.100
could exist and it could do what it did when actually it's more like a waste
00:19:24.100 --> 00:19:28.340
product and people really shouldn't be eating soy because it's so dangerous in
00:19:28.340 --> 00:19:32.860
terms of its estrogenic effect on females and males and those estrogenic
00:19:32.860 --> 00:19:36.100
effects are very pro-inflammatory. Dr. Peate you've pointed out many many
00:19:36.100 --> 00:19:42.260
occasions and I'm currently on board with that same feeling that the the
00:19:42.260 --> 00:19:45.500
irritation and the inflammation that estrogen promotes is nothing but a
00:19:45.500 --> 00:19:51.580
dangerous process in the body. And also Dr. Peate how would you compare
00:19:51.580 --> 00:19:59.620
estrogen levels with menopausal women and men? With the aging a man's
00:19:59.620 --> 00:20:06.780
estrogen pretty steadily increases but if he has a heart attack it goes up
00:20:06.780 --> 00:20:15.460
sharply or if he has a traumatic injury it goes up during the recovery time but
00:20:15.460 --> 00:20:25.180
generally there's a trend upward in men and in women when the ovaries stop
00:20:25.180 --> 00:20:34.220
cycling there up until about the age of 38 to 40 there is a an actual steady
00:20:34.220 --> 00:20:42.700
increase in estrogen and when the ovaries stop cycling they stop suddenly
00:20:42.700 --> 00:20:49.220
producing progesterone but they continue producing a considerable
00:20:49.220 --> 00:20:55.820
amount of estrogen until the body can adjust it downward. So there are a
00:20:55.820 --> 00:21:03.060
few years in the 40s or early 50s usually when estrogen is extremely
00:21:03.060 --> 00:21:11.380
excessive relative to the anti-estrogen effect of progesterone but then again
00:21:11.380 --> 00:21:17.860
after the ovaries have pretty much stopped functioning with the rest of
00:21:17.860 --> 00:21:28.340
the body as the progesterone fails all of the other tissues begin the same way
00:21:28.340 --> 00:21:35.820
that happens in men. All of a woman's tissues tend to start increasing their
00:21:35.820 --> 00:21:42.260
production of estrogen so that after menopause the fatter a woman is the more
00:21:42.260 --> 00:21:48.540
estrogen she's producing because the fat tissue is a good source of it but on any
00:21:48.540 --> 00:21:55.740
tissue after menopause to the degree that it's stressed will begin producing
00:21:55.740 --> 00:22:02.140
estrogen. So is it about the same level between men and women? Yeah. After the
00:22:02.140 --> 00:22:09.500
menopausal period? I think women tend to be fatter in old age and so they are
00:22:09.500 --> 00:22:14.860
more likely to have a higher level of estrogen but just measuring the blood
00:22:14.860 --> 00:22:24.460
estrogen gives a misleading impression because when progesterone is
00:22:24.460 --> 00:22:31.940
deficient the estrogen receptor as well as the aromatase enzyme that makes
00:22:31.940 --> 00:22:38.220
estrogen the receptors bind it in cells and there's no progesterone to destroy
00:22:38.220 --> 00:22:45.900
the estrogen receptor so it just stays in the cell and some of the enzymes that
00:22:45.900 --> 00:22:53.500
are no longer inactivated by progesterone other enzymes capture
00:22:53.500 --> 00:23:00.140
circulating estrogen that should have been excreted cause it to be deposited
00:23:00.140 --> 00:23:09.460
in cells. Still other enzymes shift any estrogen away from the estrone form to
00:23:09.460 --> 00:23:16.700
the estriol form which is the most active intense estrogen. So everything
00:23:16.700 --> 00:23:25.140
that happens when progesterone is deficient tends to load up various cells
00:23:25.140 --> 00:23:31.500
all through the body with more and more estrogenic stimulation even though it
00:23:31.500 --> 00:23:36.380
isn't being released to be measured in the blood. Right so the blood test could
00:23:36.380 --> 00:23:41.260
appear that it's fine but if you have a large amount of fat cells that could be
00:23:41.260 --> 00:23:45.460
stored in that and other tissues and what about weight loss for women who are
00:23:45.460 --> 00:23:49.740
in the menopause if they lose that weight do they then poison themselves
00:23:49.740 --> 00:23:55.020
with estrogen as it comes out of the cells? Just temporarily but it's better
00:23:55.020 --> 00:24:01.900
to get rid of it and have it local because inside the cells it produces
00:24:01.900 --> 00:24:10.500
things such as breast cancer lung cancer uterine cancer ovarian cancer all of the
00:24:10.500 --> 00:24:17.020
tissues that no longer have enough progesterone are subject to cancer. So
00:24:17.020 --> 00:24:21.540
what about the women that continue to menstruate like I heard from this lady
00:24:21.540 --> 00:24:29.780
the other day that she had a friend who was 17 was still menstruating. I talked
00:24:29.780 --> 00:24:35.300
to a gynecologist who was giving his wife progesterone and she was still
00:24:35.300 --> 00:24:46.300
menstruating at 60 and if you happen to have a very good system for producing
00:24:46.300 --> 00:24:52.300
progesterone there's no reason why it shouldn't stop at 55. There's no reason
00:24:52.300 --> 00:24:57.540
to stop at 55 then right? No. I mean basically would do you think it would be
00:24:57.540 --> 00:25:00.620
beneficial that women continue to menstruate until the day they die? I
00:25:00.620 --> 00:25:12.820
think so. Like the flamingos? Yeah flamingos have no life limitation
00:25:12.820 --> 00:25:21.820
according to ordinary mortality curves. They seemed only died by accident.
00:25:21.820 --> 00:25:28.020
Starvation right? Okay you're listening to Ask Your Doctor KMUD Galbraithville 91.1 FM
00:25:28.020 --> 00:25:31.940
from 7.30 till the end of the show. Please call in with any questions you
00:25:31.940 --> 00:25:35.500
have either related or unrelated to this month's subject. Number if you're in the
00:25:35.500 --> 00:25:42.060
area area code 707 923 3911 or for those folks in different states across the US
00:25:42.060 --> 00:25:49.140
has an 800 number which is 1-800-568-3723. Dr. Peat I wanted to pick up on a
00:25:49.140 --> 00:25:52.220
point that you mentioned during your last discourse then I did I've not had
00:25:52.220 --> 00:25:56.700
that before. Progesterone destroys the estrogen receptor. Does anything
00:25:56.700 --> 00:26:00.300
similarly happen with estrogen doing the same thing to progesterone receptors or
00:26:00.300 --> 00:26:06.060
is it just that way around? Well estrogen activates its own receptor in most
00:26:06.060 --> 00:26:16.060
tissues and it will activate inflammatory things which tend to turn
00:26:16.060 --> 00:26:22.100
off the progesterone receptor if you have an excess.
00:26:22.100 --> 00:26:33.300
Generally the normal function would be for progesterone to rise as soon as the
00:26:33.300 --> 00:26:40.300
estrogen has had its surge and then knock it out. The estrogen is fine if
00:26:40.300 --> 00:26:46.820
it's active only for 12 to 24 hours every month. Right, right. It does its job and
00:26:46.820 --> 00:26:51.020
then it's finished. But like you said the tissues will carry on producing estrogen
00:26:51.020 --> 00:26:57.260
especially in obese individuals and menopause or even postmenopausal
00:26:57.260 --> 00:27:03.620
women. Yeah Alexander Lipschutz showed that if you remove the ovaries and then
00:27:03.620 --> 00:27:11.860
implant just a tiny estrogen releasing pellet just a very small but continuous
00:27:11.860 --> 00:27:19.620
dose it's very carcinogenic. But if you interrupt that or even a large dose with
00:27:19.620 --> 00:27:26.100
estrogen with progesterone periodically you don't get cancer. And in his
00:27:26.100 --> 00:27:34.660
experiments the estrogen uninterrupted was carcinogenic to uterus, breast, lungs,
00:27:34.660 --> 00:27:41.700
kidneys, brain and intestine. Yeah. Basically everything. Okay so just
00:27:41.700 --> 00:27:46.700
another another call for all the ladies out there. There really is nothing I
00:27:46.700 --> 00:27:50.180
know it's a personal thing but there's nothing wrong with continuing your
00:27:50.180 --> 00:27:54.020
menstrual cycle as long as you possibly can. Progesterone is your friend,
00:27:54.020 --> 00:27:58.140
estrogen is your enemy and the only thing really that estrogen is any good
00:27:58.140 --> 00:28:02.380
for is the implantation. So I may have a first caller so let's get this first
00:28:02.380 --> 00:28:09.420
caller on the air. Caller where are you from? I'm from Kansas City. Did you say Kansas City?
00:28:09.420 --> 00:28:18.020
Yeah Kansas City. Oh hey welcome to the show. Thanks. Hi Dr. Peat. What do you think is
00:28:18.020 --> 00:28:22.580
happening if someone experiences digested cramps and bloating within 30 minutes
00:28:22.580 --> 00:28:27.180
when using vitamin E orally and which still occurs even when switching to a
00:28:27.180 --> 00:28:31.780
few different products as well as even when using several drops of progeste
00:28:31.780 --> 00:28:41.660
which also contains vitamin E? I think it's the viscous oily quality that is
00:28:41.660 --> 00:28:50.860
irritating. Some people have that reaction for example if they try to
00:28:50.860 --> 00:28:57.300
use it in their armpit where the skin is very sensitive the highly viscous oil
00:28:57.300 --> 00:29:04.620
can be very irritating so I think it should be taken with food so that it
00:29:04.620 --> 00:29:10.500
doesn't hit any of the membranes in the concentrated form. Do you think it's
00:29:10.500 --> 00:29:22.020
possible to develop a soy allergy somewhere along the way? Yeah many people
00:29:22.020 --> 00:29:30.340
do have soy allergies but the oil doesn't contain any of the proteins that
00:29:30.340 --> 00:29:40.100
people are allergic to so I haven't heard of any documented allergy to oily
00:29:40.100 --> 00:29:48.060
soy products such as soy oil. Okay do you think it's possible that for that person
00:29:48.060 --> 00:29:52.020
that's something like 400 units international units of the
00:29:52.020 --> 00:29:57.220
alpha-tocopherol with 300 milligrams of gamma, delta and beta-tocopherol is
00:29:57.220 --> 00:30:02.220
excessive and possibly being excreted mostly in bile which is alkaline and
00:30:02.220 --> 00:30:06.220
possibly irritating to an already irritated intestine which would maybe
00:30:06.220 --> 00:30:17.580
cause the cramps and bloating? I doubt it because the effect of vitamin E on many
00:30:17.580 --> 00:30:24.740
cell processes is anti-inflammatory for example it inhibits prostaglandin
00:30:24.740 --> 00:30:35.620
formation similar to aspirin in its range of anti-inflammatory effects.
00:30:36.620 --> 00:30:40.780
Okay that's great thank you. All right thank you for your call. We do have another call
00:30:40.780 --> 00:30:44.180
on the air so let's take this next caller. Caller where are you from?
00:30:44.180 --> 00:30:49.580
Hi I'm calling from Mexico. Mexico, the first caller from Mexico. Welcome to the
00:30:49.580 --> 00:30:56.460
show what's your question? Thanks hi if I understood correctly earlier you were
00:30:56.460 --> 00:31:04.020
talking about how taking extra iodine can interact with PUFA to cause problems
00:31:04.020 --> 00:31:12.460
and I know someone who took a few milligrams of extra iodine and she went
00:31:12.460 --> 00:31:21.100
into a some kind of thyroid hyperthyroid like crisis state where she couldn't
00:31:21.100 --> 00:31:27.420
tolerate any physical exertion. Her muscles were really weak and her pulse
00:31:27.420 --> 00:31:35.540
was very high and years later she still gets that reaction from thyroid and I
00:31:35.540 --> 00:31:44.860
was wondering if that's related to iodine? Back in the years when many people
00:31:44.860 --> 00:31:56.180
were in certain regions for example in southern Mexico, western China and Ohio
00:31:56.180 --> 00:32:03.860
Eastern Europe those areas were very deficient in iodine and they would
00:32:03.860 --> 00:32:10.500
develop an enlargement of the thyroid gland and then when they ate iodine even
00:32:10.500 --> 00:32:17.700
a fairly normal amount suddenly their gland would start forming thyroid hormone
00:32:17.700 --> 00:32:27.300
and if the goiter was very big they could have serious hyperthyroidism that
00:32:27.300 --> 00:32:33.700
could last for years but if the gland was just slightly swollen it would pass
00:32:33.700 --> 00:32:42.060
in about two months. So that's a that's a very real sequelae of using iodine in
00:32:42.060 --> 00:32:48.140
that particular individual that they would have that increased thyroid
00:32:48.140 --> 00:32:51.700
production that would be you know resulting in what the callers just
00:32:51.700 --> 00:32:57.380
mentioned? Yeah if they took their iodine in the form of thyroid hormone they could
00:32:57.380 --> 00:33:05.340
normalize their body functions and be replacing iodine in a limited
00:33:05.340 --> 00:33:09.820
graded fashion so that they wouldn't go into those hyperthyroid states and
00:33:09.820 --> 00:33:16.340
getting the required amount of hormone would cause their pituitary to settle
00:33:16.340 --> 00:33:22.300
down and let the gland gradually shrink. Because that is treatment for goiter is
00:33:22.300 --> 00:33:28.300
that you supplement with thyroid hormone? Yes to treat hyperthyroidism
00:33:28.300 --> 00:33:34.860
the safest thing is to supplement usually with thyroid hormone. So again
00:33:34.860 --> 00:33:39.120
just to just to expand on the very first question to Dr. Peate about the nascent
00:33:39.120 --> 00:33:44.140
iodine it's not a good idea and also many other forms of iodine
00:33:44.140 --> 00:33:48.660
supplementation is not necessary and if you need iodine and you have any kind of
00:33:48.660 --> 00:33:52.900
low thyroid actually thyroid hormone is the best way to get bound iodine. Okay
00:33:52.900 --> 00:33:58.340
did you have anything else you wanted to bring out caller? Well thanks a lot I was
00:33:58.340 --> 00:34:03.540
just wondering if it you know if it would be a good idea to do anything
00:34:03.540 --> 00:34:10.740
specific to try to rectify this this problem or if there's any tips on
00:34:10.740 --> 00:34:17.620
tolerating thyroid does avoiding iodine help in a situation like that? The people
00:34:17.620 --> 00:34:25.500
who have trouble with the actual thyroid hormone they can be either deficient in
00:34:25.500 --> 00:34:32.540
magnesium because hypothyroidism makes all of your tissues fail to retain a
00:34:32.540 --> 00:34:38.020
normal amount of magnesium and then when you supplement it suddenly you
00:34:38.020 --> 00:34:44.300
experience an extreme magnesium deficiency in your heart for example and
00:34:44.300 --> 00:34:51.940
your brain and so taking some magnesium at the same time as the thyroid it will
00:34:51.940 --> 00:34:59.380
help those people. Others if they're deficient in adrenal or ovarian or
00:34:59.380 --> 00:35:08.220
gonadal steroids will suffer stress symptoms when they take thyroid and and
00:35:08.220 --> 00:35:14.860
so using a supplement such as pregnenolone will make them tolerate
00:35:14.860 --> 00:35:20.060
adapting to the thyroid more easily. And what about Dr. Peat how some people if
00:35:20.060 --> 00:35:25.220
they supplement with t4 thyroxine they will have those symptoms like our caller
00:35:25.220 --> 00:35:29.260
mentioned where their muscles are weak and they their hearts pounding they're
00:35:29.260 --> 00:35:33.460
pulses high and isn't that because if they're already low thyroid and they
00:35:33.460 --> 00:35:36.580
take the t4 then they're actually stimulating the adrenaline because
00:35:36.580 --> 00:35:42.300
they're not converting it? Yeah when when people have suffered for a long time
00:35:42.300 --> 00:35:48.940
with low thyroid they're likely to have extremely high adrenaline and cortisol