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WEBVTT
00:00:00.000 --> 00:00:06.000
The following interview with Ray Peat was recorded on May 18, 2012.
00:00:06.000 --> 00:00:11.000
If you'd like more information about Dr. Raymond Peat, you can go to his website,
00:00:11.000 --> 00:00:16.000
RayPeat.com, R-A-Y-P-E-A-T dot com,
00:00:16.000 --> 00:00:21.000
where there's many interesting articles for free available for your enjoyment.
00:00:21.000 --> 00:00:24.000
Also, if you're interested in hearing this show again,
00:00:24.000 --> 00:00:31.000
many politics and science shows are posted at RadioNumeral4All.net,
00:00:31.000 --> 00:00:38.000
RadioNumber4All.net, and when you get there, search for "politics and science."
00:00:38.000 --> 00:00:44.000
Hello and welcome to "Politics and Science." I'm John Barkhausen, your host,
00:00:44.000 --> 00:00:50.000
and today we're going to talk about some autoimmune diseases and some movement disorder dysfunctions.
00:00:50.000 --> 00:00:55.000
I'm intrigued by them not only because I have friends that are suffering from these,
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but also because the medical world offers so little knowledge about the diseases
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and so little hope or practical knowledge in terms of treatment for what to do to help people.
00:01:05.000 --> 00:01:10.000
I'm very happy that Dr. Raymond Peat is here to join me again today.
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Dr. Peat has a Ph.D. in biology from the University of Oregon
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and extensive knowledge of science history.
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There are many theories as to the causes of the diseases,
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and one common factor that is present in all of them and that most people agree on is inflammation.
00:01:27.000 --> 00:01:33.000
Ray, I just want to start off by asking you why is so little understood about these diseases?
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Well, I think there's a lot more known than the public is aware of.
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The medical journals aren't a good place to look
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if you're just wanting to find out how much is known,
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but if you read widely in not only medical journals but general science journals,
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you see that people have discovered really interesting things about all of them
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and that there are patterns that show up across the various diseases
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that I think really things could be put into practice more than they are.
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And there are people demonstrating improvement in the degenerative diseases
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with very simple antioxidant supplements and creatine supplements and such
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that you just don't hear about in the New York Times stories about advances in health.
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I think part of it is that when a generic substance looks like it might prevent
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or cure one of these horrible conditions, the drug industry isn't interested,
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so there's no advertising money to be made by running publicity about it.
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So nobody pursues it.
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Ray, can you explain where you're finding out this knowledge of hopeful techniques
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to combat these diseases?
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A lot of it you can find right in PubMed and Google.
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A lot of it in more obscure journals, but there's enough to keep a person busy for years
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just putting pieces together like making a meaningful puzzle out of scraps
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from the various lines of thinking.
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Like if you follow one disease over 20 or 30 years, like Alzheimer's,
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there are a number of styles focusing on the cholinergic nerve death
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or the accumulating fibrils, amyloid and such,
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and explaining that as a toxin that causes the disease.
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And the various different diseases, each one goes through its styles
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and what they think is interesting, but the pressure on funding the research and such
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pushes generally towards a genetic explanation that makes a simple drug solution conceivable,
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like something to stop that one genetic defect from taking its effect.
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So when you say styles, are you talking about there's certain fads in research
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that are prevalent at certain times?
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Yeah, definitely fads, but the basic big fad that has lasted for 100 years
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is the genetic explanation.
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Like in Huntington's disease, it's a certain repeat that causes a series of glutamine amino acids
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in the protein to increase, and that creates a protein that shows up as if it's doing damage.
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And so the framework idea is that the gene expresses itself in a protein
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and the protein causes the symptoms of the disease,
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and so it's the idea that the gene is causing the disease.
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But there are several ways of approaching that.
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One is that something is causing this repeat to be formed in the gene itself.
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For example, they've noticed that generations,
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even though typically Huntington's is thought to set in at the age of 40 or so,
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they've noticed that the children of those people develop about eight years earlier,
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and each generation anticipates and starts the condition earlier.
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So there's something causing that repeat in the protein to increase each generation,
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and that is something that's slow to sink into the genetic causality that things are happening right now,
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each generation creating a tendency to mutate in a certain direction.
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There were many genetic theories that said that mutations do have a directionality,
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and they used to explain the growth of corn antlers on elks and swans getting bigger and bigger
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because of some tendency in the organism to go in a certain direction.
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Orthogenesis, they called it, but that was sort of vaguely anti-Darwinian
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and inclined towards Lamarckism, and so it dropped out.
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But the idea of a defect in the gene that causes it to get worse and worse quickly with each generation
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is more acceptable because in immunology, that was a solution to how antibodies can adapt so quickly
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to any conceivable infection or antigen.
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They said they have to adapt by mutating so fast that they can evolve in just a few days
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to match whatever antigen they're exposed to.
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So this idea of almost directed mutation got put into genetics by way of immunology,
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and there are the trends in a few places.
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John Cairns and Ted Steele are the people known to be working on the idea of directed mutations
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in a constructive way, not just destructive.
00:09:02.000 --> 00:09:09.000
Yeah, I'm awfully confused by this because I think of geneticists as saying, in the past at least,
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that genes were a permanent thing that were passed down from generation to generation
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and could not be changed easily.
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Yeah, they have been open to the idea, but they're still not seeing it as anything deliberate
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or constructive, just a way the defect can develop.
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It's a way to save the genetic causality rather than seeing that the same thing causing the symptoms
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of the disease might also be causing the genes to change in the same direction.
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That's what they don't want to see is a link between the way the gene changes and the function of the protein
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in the life of the individual organism.
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That's where it implies Lamarckism.
00:10:12.000 --> 00:10:17.000
You mean that the organism is directing the gene mutation?
00:10:17.000 --> 00:10:29.000
Yeah, or that something is causing the organism on the cellular, not genetic level, to change
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at the same time that the gene that regulates that cellular function is changing in the same direction.
00:10:36.000 --> 00:10:46.000
They shouldn't be coordinated that way so that the function and the gene change simultaneously
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or even with the information going from the function into the gene and then back out.
00:10:53.000 --> 00:11:01.000
Because that would mean that the organism is a propulsive being on the evolutionary level.
00:11:01.000 --> 00:11:04.000
Yeah, exactly.
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That's the whole point ever since the anti-Darwinians in the 19th century, Weissmann in particular,
00:11:16.000 --> 00:11:25.000
they hated the idea that things could be changing meaningfully or purposefully
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and wanted to say that there is no real change and genes were the way of proving that you might get a different mixture of traits
00:11:37.000 --> 00:11:44.000
but the traits are eternal and the gene is what causes that.
00:11:44.000 --> 00:11:54.000
One of the people questioning this, James Shapiro, was working along in ordinary bacterial genetics
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and he noticed that individuals exposed to an antibiotic could become resistant to it
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and that they could pass that information on very intentionally to their neighbors
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and even across varieties of one bacteria to another and spread it through whole systems
00:12:20.000 --> 00:12:26.000
and that got him thinking about this idea of purposive change
00:12:26.000 --> 00:12:40.000
and he's proposed that the organism does genetic engineering along the lines of what Barbara McClintock was talking about
00:12:40.000 --> 00:12:56.000
but he says this is the general way genetics works in the organism, that the organism is its own genetic engineer doing changes for its own benefit.
00:12:56.000 --> 00:13:03.000
Yeah, I can believe it because I was looking today at a physiology book trying to understand the nervous system
00:13:03.000 --> 00:13:09.000
because a lot of the diseases we started off talking about are diseases of the nervous system
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and it's pretty phenomenal if you open up an encyclopedia and look at how the nervous system is laid out.
00:13:15.000 --> 00:13:27.000
It's an awe-inspiring system and the idea that some scientists and philosophers think that that happened by random evolutionary trial and error
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seems impossible to my mind.
00:13:30.000 --> 00:13:42.000
Yeah, the establishment genetics biology system including most of medicine are attacking James Shapiro
00:13:42.000 --> 00:13:49.000
with his application of the Barbara McClintock way of thinking.
00:13:49.000 --> 00:13:56.000
And what was your point?
00:13:56.000 --> 00:14:01.000
The complexity and organization of it is.
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Randomness is such a deep part of their way of thinking that they are accusing Shapiro of being a creationist
00:14:13.000 --> 00:14:21.000
and he says well the creationists sometimes speak very reasonably
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and sometimes the so-called neo-Darwinians don't speak so scientifically and reasonably
00:14:28.000 --> 00:14:38.000
and so he is attacking the science invoking creations because sometimes their arguments are positive.
00:14:38.000 --> 00:14:45.000
Yeah, I mean I don't personally buy into the father figure in the sky looking down on us all.
00:14:45.000 --> 00:14:49.000
No, but he's saying that the organism itself is creating.
00:14:49.000 --> 00:14:57.000
That life has intelligence you've said before and that to me has the ring of truth to it
00:14:57.000 --> 00:15:04.000
because as you look around the world and see basically as you say the world organizing itself
00:15:04.000 --> 00:15:08.000
it's a good example of the intelligence all around us.
00:15:08.000 --> 00:15:15.000
And one of the things that sort of interested me that Carl Lindgren said in his book Cold War in Biology
00:15:15.000 --> 00:15:21.000
was that in order to practice science back in the 40s and 50s in the United States
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it was very helpful to profess some kind of belief in a god in order to keep your job.
00:15:27.000 --> 00:15:33.000
He said that professors were afraid to say they were an atheist or agnostic.
00:15:33.000 --> 00:15:44.000
Yeah, all of my professors were churchgoers which used to be in the 19th century.
00:15:44.000 --> 00:15:49.000
They tended to be agnostics, biologists specifically.
00:15:49.000 --> 00:15:59.000
But it really did get a religious boost in the 1940s with the anti,
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they considered it anti-materialist but what it was was a different kind of materialism,
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randomness based materialism rather than the idea that material is part of the purpose of intelligent life process.
00:16:19.000 --> 00:16:28.000
Bringing this back to our topic today and talking about the inflammation that appears to be present
00:16:28.000 --> 00:16:34.000
in all of these diseases we're talking about whether we're talking about amyotrophic lateral sclerosis
00:16:34.000 --> 00:16:40.000
which is ALS or Lou Gehrig's disease or multiple sclerosis which you've written about quite a bit
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or rheumatoid arthritis, all these diseases which they don't really have any known cause or cure for
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involve inflammation and maybe you could outline for us how science has perceived inflammation over the years.
00:17:00.000 --> 00:17:12.000
In the middle of the 20th century there was a heavy concentration on inflammation as a reaction to infection
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to the extent that about 40 years ago, 35 years ago when I mentioned to a recent graduate something about
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sterile inflammation she wouldn't let me continue and said there's no such thing as sterile inflammation.
00:17:31.000 --> 00:17:41.000
But in 1900 and before people were demonstrating that you could extract something from infectious organisms
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that would create inflammation even if it was sterile and then with radiation experiments
00:17:47.000 --> 00:17:58.000
they found that radiation created inflammation or trauma, completely sterile burns,
00:17:58.000 --> 00:18:07.000
shutting off the blood supply creates inflammation and I think the only way to approach inflammation
00:18:07.000 --> 00:18:19.000
is to think of it as a gap that shouldn't exist between the demands made on the cells or the tissue
00:18:19.000 --> 00:18:23.000
and the resources to meet those demands.
00:18:23.000 --> 00:18:33.000
If you traumatize or over stimulate a tissue or if you don't provide enough sugar and oxygen and carbon dioxide
00:18:33.000 --> 00:18:41.000
to meet that stimulation, to hold the stimulation under control, then things go wrong
00:18:41.000 --> 00:18:53.000
and the tissue becomes edematous and chain reactions happen that can kill the tissue
00:18:53.000 --> 00:19:05.000
or if the organism can manage to recruit enough systems to provide sugar for example
00:19:05.000 --> 00:19:10.000
and to stop the excitation then it can heal.
00:19:10.000 --> 00:19:18.000
A little inflammation rouses the organism to cause regeneration
00:19:18.000 --> 00:19:23.000
otherwise it can lead to fibrosis and atrophy.
00:19:23.000 --> 00:19:30.000
So let's use an example of one of these diseases like multiple sclerosis.
00:19:30.000 --> 00:19:37.000
The myelin sheath for some unknown reason according to the medical authorities
00:19:37.000 --> 00:19:42.000
becomes worn away or taken away and the nerves stop functioning
00:19:42.000 --> 00:19:44.000
and people start having trouble with motor control.
00:19:44.000 --> 00:19:49.000
They say it's caused by inflammation and how does that relate to your idea?
00:19:49.000 --> 00:19:53.000
I think it causes a lack of energy.
00:19:53.000 --> 00:20:04.000
It will cause a tissue to swell up, take up water and as it swells up the tissue tries to renew itself.
00:20:04.000 --> 00:20:09.000
Cells are always renewing themselves in a tremendous churning process
00:20:09.000 --> 00:20:13.000
of taking down the old stuff and putting up new stuff.
00:20:13.000 --> 00:20:22.000
For example, someone said that during the night I think it was 60% of our molecules in our brain,
00:20:22.000 --> 00:20:30.000
the fat substance that's a big part of the brain, 60% of them are totally re-synthesized every night
00:20:30.000 --> 00:20:41.000
and just an hour after death a massive amount of the brain substance has decomposed
00:20:41.000 --> 00:20:45.000
because it isn't constantly being reconstituted.
00:20:45.000 --> 00:20:56.000
So you have to think in terms of a healthy stable organism as being in extremely intense turnover processes.
00:20:56.000 --> 00:21:05.000
And so if you cut off the energy supply the first thing that happens is the cell takes up water
00:21:05.000 --> 00:21:10.000
and that excites the restorative process to run faster.
00:21:10.000 --> 00:21:16.000
But if it takes up more and more water that shifts the whole direction
00:21:16.000 --> 00:21:22.000
and the cell at a certain stage of excitation will de-differentiate
00:21:22.000 --> 00:21:30.000
and try to turn into a stem cell to grow new tissue as a healing process.
00:21:30.000 --> 00:21:35.000
And if there's even less energy then that process stops.
00:21:35.000 --> 00:21:45.000
But when you have just a chronic slight energy deprivation you get a chronic slight edema
00:21:45.000 --> 00:21:51.000
and that edema one of the things that happens is that the myelin swells up
00:21:51.000 --> 00:21:59.000
and while it's being taken down it isn't being re-synthesized efficiently.
00:21:59.000 --> 00:22:11.000
Thyroid, progesterone, pregnenolone and saturated fatty acids are things that support the reforming of the myelin.
00:22:11.000 --> 00:22:19.000
And when the energy is down for example thyroid is low then you can't make the pregnenolone and progesterone
00:22:19.000 --> 00:22:25.000
and so you just can't synthesize it as fast as it's being taken down.
00:22:25.000 --> 00:22:30.000
So it's really a condition where you're put under stress
00:22:30.000 --> 00:22:37.000
and you don't have the energy resources to keep rebuilding yourself under that stress.
00:22:37.000 --> 00:22:49.000
Yeah and it's just remarkably similar in the processes in the degenerative brain diseases of aging
00:22:49.000 --> 00:22:58.000
or the development of cancer or of deforming arthritis,
00:22:58.000 --> 00:23:05.000
inflammation, chronic inflammation like pancreatitis, hepatitis, chronic kidney disease and so on.
00:23:05.000 --> 00:23:15.000
All the same processes are involved just in different proportions of energy supply and irritation or stimulation.
00:23:15.000 --> 00:23:19.000
Is that what Georgie referred to as the condition of being sick?
00:23:19.000 --> 00:23:21.000
Yeah, that was Hanselier.
00:23:21.000 --> 00:23:23.000
Oh, it was Hanselier, thank you.
00:23:23.000 --> 00:23:27.000
Yeah and that's just a shortage of energy basically.
00:23:27.000 --> 00:23:35.000
Yeah, I think the gap between stimulation and energy resources,
00:23:35.000 --> 00:23:40.000
it's been used to define excitotoxicity that kills brain cells
00:23:40.000 --> 00:23:46.000
but it's really the same process in your pancreas or kidney or skin
00:23:46.000 --> 00:23:51.000
and you are exactly the same energy systems.
00:23:51.000 --> 00:23:57.000
Slight differences in the particular proteins that are like in Huntington's disease,
00:23:57.000 --> 00:24:04.000
there's that polyglutamine repeat that accumulates
00:24:04.000 --> 00:24:12.000
but it's really just a symptom of an inflammatory state
00:24:12.000 --> 00:24:16.000
with a particular history that leads to that being a problem.
00:24:16.000 --> 00:24:20.000
But the fact that it usually waits until you're 40 years old
00:24:20.000 --> 00:24:26.000
means that the same with rheumatoid arthritis or Crohn's disease
00:24:26.000 --> 00:24:29.000
or any of these chronic inflammatory things,
00:24:29.000 --> 00:24:34.000
they almost never develop in little kids.
00:24:34.000 --> 00:24:38.000
It takes a while being exposed to certain environments
00:24:38.000 --> 00:24:41.000
for each kind of thing to develop.
00:24:41.000 --> 00:24:47.000
But there are a few common factors in the organism and its environment
00:24:47.000 --> 00:24:51.000
that are involved in almost all of these.
00:24:51.000 --> 00:24:55.000
Alzheimer's, Parkinson's disease,
00:24:55.000 --> 00:24:59.000
Lou Gehrig's disease, Huntington's,
00:24:59.000 --> 00:25:05.000
the various nervous dementia diseases and--
00:25:05.000 --> 00:25:07.000
MS.
00:25:07.000 --> 00:25:14.000
Yeah, and the skeletal nervous inflammatory--
00:25:14.000 --> 00:25:19.000
diabetes even involves inflammation
00:25:19.000 --> 00:25:22.000
and the failure to regenerate properly.
00:25:22.000 --> 00:25:28.000
Beta cells are being killed in the same way that brain cells are being killed, basically.
00:25:28.000 --> 00:25:34.000
And instead of making insulin, as the cells are renewed,
00:25:34.000 --> 00:25:39.000
the cells are killed as fast as they're renewed, so they stop making insulin.
00:25:39.000 --> 00:25:44.000
But if you stop killing them, then they can start making insulin again.
00:25:44.000 --> 00:25:46.000
Same with the brain.
00:25:46.000 --> 00:25:48.000
If you stop killing the brain,
00:25:48.000 --> 00:25:52.000
it's always in the process of repair and regeneration.
00:25:52.000 --> 00:25:58.000
I might have mentioned a man with ALS that I talked to about, I guess,
00:25:58.000 --> 00:26:02.000
eight or 10 years ago, 70 years old.
00:26:02.000 --> 00:26:10.000
And he had had all the best neurologists examine him,
00:26:10.000 --> 00:26:15.000
and he absolutely was convinced he had Lou Gehrig's disease
00:26:15.000 --> 00:26:21.000
and was declining the same as other people he met in the neurology offices.
00:26:21.000 --> 00:26:31.000
And he decided to start doing things to stop inflammation and support repair.
00:26:31.000 --> 00:26:36.000
And he did them consistently for a few months while still declining.
00:26:36.000 --> 00:26:42.000
But then he stopped declining and within a few months was repaired.
00:26:42.000 --> 00:26:46.000
It was less than a year of the whole process.
00:26:46.000 --> 00:26:51.000
And people he had met in the neurology offices went ahead
00:26:51.000 --> 00:26:59.000
with the same rate of decline and were totally disabled by the time he was totally well.
00:26:59.000 --> 00:27:01.000
That's impressive.
00:27:01.000 --> 00:27:06.000
So one of the things you've talked about in terms of helping your body rebuild
00:27:06.000 --> 00:27:09.000
from conditions like this is basically a very simple thing,
00:27:09.000 --> 00:27:11.000
just keeping your blood sugar up.
00:27:11.000 --> 00:27:15.000
Maybe you can describe what happens when somebody is low on blood sugar,
00:27:15.000 --> 00:27:20.000
reading you talking about what happens, basically this catabolic effect that happens
00:27:20.000 --> 00:27:24.000
in your body just from low blood sugar, to my mind is pretty convincing
00:27:24.000 --> 00:27:28.000
about how important it is to keep your blood sugar up.
00:27:28.000 --> 00:27:33.000
Yeah, the first thing when your blood sugar falls because your liver
00:27:33.000 --> 00:27:38.000
hasn't stored enough glycogen to turn into glucose,
00:27:38.000 --> 00:27:44.000
the first reaction is for adrenaline to increase to try to squeeze more glycogen
00:27:44.000 --> 00:27:48.000
into your circulation for your brain primarily.
00:27:48.000 --> 00:27:57.000
And when the glycogen is absolutely gone, the adrenaline keeps activating the breakdown
00:27:57.000 --> 00:28:07.000
of fat and provides increased amounts of circulating fat to make up for the lack of sugar.
00:28:07.000 --> 00:28:17.000
But after the fat becomes a source of energy, your cells still need some sugar
00:28:17.000 --> 00:28:24.000
to maintain their basic processes, and so they turn protein into sugar.
00:28:24.000 --> 00:28:33.000
And to do that, they increase cortisol, which breaks down muscle, skin, thymus gland.
00:28:33.000 --> 00:28:39.000
The thymus is the first to go, and the cortisol will eat up your muscle and skin
00:28:39.000 --> 00:28:48.000
and immune system pretty quickly to feed your heart, lungs, and brain to keep them alive.
00:28:48.000 --> 00:28:56.000
And so every time your blood sugar falls, you're shifting over to fat metabolism
00:28:56.000 --> 00:29:06.000
and breaking down protein so that your muscles are one of the places that store glycogen.
00:29:06.000 --> 00:29:10.000
So as your muscles get smaller, then more burden is put on your liver
00:29:10.000 --> 00:29:19.000
to keep your blood sugar steady, and that makes your liver progressively suffer.
00:29:19.000 --> 00:29:28.000
And eventually it gets to the point that your brain isn't getting either the right energy
00:29:28.000 --> 00:29:31.000
or the right kind of energy.
00:29:31.000 --> 00:29:36.000
But one of the things that happens with aging is that we progressively,
00:29:36.000 --> 00:29:43.000
from the time we're born at birth, we're very highly saturated in our fats
00:29:43.000 --> 00:29:50.000
because they've been formed from glucose in utero, and we can only make saturated,
00:29:50.000 --> 00:30:01.000
monounsaturated, and omega-9 unsaturated fats when we're supplied with either sugar or protein.
00:30:01.000 --> 00:30:05.000
But once we start eating in the ordinary environment,
00:30:05.000 --> 00:30:11.000
our tissues start loading up on the polyunsaturated from the environment.
00:30:11.000 --> 00:30:22.000
By the time a person is 40, the brain is pretty full of either the arachidonic acid series,
00:30:22.000 --> 00:30:33.000
or if they have eaten a lot of fish, there will be mostly the long, highly unsaturated fats,
00:30:33.000 --> 00:30:42.000
which will mostly be the DHA type of fish oil-derived omega-3 fats.
00:30:42.000 --> 00:30:50.000
And even with a pretty average diet, the old person's brain is very highly biased
00:30:50.000 --> 00:30:54.000
towards the DHA type fats.
00:30:54.000 --> 00:31:06.000
And if you look at Parkinson's disease, their favorite genetic protein that some people like to say
00:31:06.000 --> 00:31:14.000
is the cause of Parkinson's disease, synuclein is the Parkinson's equivalent
00:31:14.000 --> 00:31:26.000
of the glutamine repeat of Huntington's or the amyloid or tau fibrils of Alzheimer's disease.
00:31:26.000 --> 00:31:32.000
Each disease tends to have its own protein that goes haywire.
00:31:32.000 --> 00:31:45.000
In the case of Parkinson's, it's the alpha-synuclein, and DHA, the fish type of unsaturated fat,
00:31:45.000 --> 00:31:55.000
causes the synuclein protein to change to its toxic form that appears in Parkinson's disease.
00:31:55.000 --> 00:32:00.000
And saturated fats tend to protect against that.
00:32:00.000 --> 00:32:08.000
So very clearly in Parkinson's, you can see the role of fat in inclining the brain
00:32:08.000 --> 00:32:12.000
towards that degenerative change in the protein.
00:32:12.000 --> 00:32:22.000
And since pretty much everyone in the environment accumulates these highly unsaturated fats,
00:32:22.000 --> 00:32:29.000
especially in the brain, but in all tissues, with aging, by the time you're 30 or 40,
00:32:29.000 --> 00:32:36.000
you become more and more susceptible to all of the degenerative inflammatory diseases,
00:32:36.000 --> 00:32:42.000
very much in proportion to the unsaturated fats.
00:32:42.000 --> 00:32:50.000
And you can find the breakdown products corresponding to the seriousness of Alzheimer's disease
00:32:50.000 --> 00:32:55.000
or Huntington's or multiple sclerosis.
00:32:55.000 --> 00:33:08.000
The specific breakdown products, such as acrolein, which comes largely from the omega-3 fats,
00:33:08.000 --> 00:33:15.000
the various reactive breakdown products show that these unstable fats are breaking down
00:33:15.000 --> 00:33:21.000
at an increased rate in the degenerative brain conditions.
00:33:21.000 --> 00:33:27.000
I see. And you've also, in that sort of cascade of bad effects from low blood sugar,
00:33:27.000 --> 00:33:34.000
after the free fatty acids are released, you said that actually pulls down your whole thyroid system.
00:33:34.000 --> 00:33:36.000
And maybe you could talk about that.
00:33:36.000 --> 00:33:44.000
Yes. A series of studies in France about 30 years ago, 25 to 30,
00:33:44.000 --> 00:33:52.000
showed that exactly in proportion to the number of double bonds in the fat,
00:33:52.000 --> 00:33:59.000
increasing from a purely saturated fat, such as uric acid or palmitic acid,
00:33:59.000 --> 00:34:07.000
through oleic acid, increasing with linoleic, even more with linoleic,
00:34:07.000 --> 00:34:14.000
and then greatly with the five and six double bonds.
00:34:14.000 --> 00:34:22.000
Each increased double bond impairs the thyroid function at the level of secretion,
00:34:22.000 --> 00:34:25.000
transport, and response.
00:34:25.000 --> 00:34:32.000
They looked at four different systems, different kinds of response in the cell.
00:34:32.000 --> 00:34:39.000
But every one of these was impaired in proportion to the degree of unsaturation
00:34:39.000 --> 00:34:43.000
of the free fatty acids in the blood.
00:34:43.000 --> 00:34:45.000
When was that study done, Ray?
00:34:45.000 --> 00:34:53.000
In the '80s, in the Annals of Endocrinology, a French journal.
00:34:53.000 --> 00:34:57.000
Well, they are traditionally, and up into recent history,
00:34:57.000 --> 00:35:01.000
the kings of using saturated fat in their cooking.
00:35:01.000 --> 00:35:05.000
French cuisine is known for its use of butter.
00:35:05.000 --> 00:35:14.000
Well, the French have fallen for the propaganda against saturated fats
00:35:14.000 --> 00:35:23.000
and cholesterol and so on, to the extent that some of their famous fat researchers
00:35:23.000 --> 00:35:28.000
were convinced that giving a fish oil supplement to pregnant women
00:35:28.000 --> 00:35:32.000
would make their babies smarter, even though animal studies showed
00:35:32.000 --> 00:35:38.000
that in proportion to the unsaturation of the fat in the pregnant animal's diet,
00:35:38.000 --> 00:35:42.000
the baby's brains were smaller and less able to learn.
00:35:42.000 --> 00:35:50.000
But anyway, the French fed some pregnant women the unsaturated fats,
00:35:50.000 --> 00:36:00.000
while measuring the fetus's ability to react to sounds applied to the abdomen.
00:36:00.000 --> 00:36:06.000
And they found that contrary to what they believed would happen,
00:36:06.000 --> 00:36:14.000
the learning was impaired by the diet with more of the highly unsaturated fats.
00:36:14.000 --> 00:36:20.000
And when the babies were born, in line with the animal experiments,
00:36:20.000 --> 00:36:22.000
their growth was retarded.
00:36:22.000 --> 00:36:29.000
Well, that seems really immoral to be testing that theory out on infants and their mothers.
00:36:29.000 --> 00:36:36.000
Well, the publicity of the animal studies has pretty much suppressed the fact
00:36:36.000 --> 00:36:44.000
that these fats didn't have consistently good effects on brain and eye development,
00:36:44.000 --> 00:36:52.000
but what got publicized were the few studies showing what were interpreted to be good studies.
00:36:52.000 --> 00:36:59.000
And on the basis of that, the baby food industry was allowed to add these things
00:36:59.000 --> 00:37:03.000
to their powdered milk for making baby formula.
00:37:03.000 --> 00:37:11.000
But even in the powdered milk, they're so unstable that breakdown products,
00:37:11.000 --> 00:37:17.000
toxic oxidation fragments, are just tremendously increased in these baby food additives.
00:37:17.000 --> 00:37:24.000
But still, the publicity is such that they're promoted as protective.
00:37:24.000 --> 00:37:30.000
So currently, as it stands today, baby formula that people are using
00:37:30.000 --> 00:37:33.000
has the DHA oils in them?
00:37:33.000 --> 00:37:37.000
A lot of them do. I don't know if there are some without it.
00:37:37.000 --> 00:37:41.000
Yeah, that's a little discouraging.
00:37:41.000 --> 00:37:45.000
Yeah, I can see adults, you know, going along with different fats
00:37:45.000 --> 00:37:50.000
and trying things out for themselves, but when you start experimenting with infants,
00:37:50.000 --> 00:37:52.000
it seems like not a very good idea.
00:37:52.000 --> 00:37:59.000
One of the things that happens at the same time these unsaturated fats are accumulating in the body
00:37:59.000 --> 00:38:08.000
is that the ratio of estrogen to progesterone in the body is increasing.