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alignment_simd.c
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alignment_simd.c
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#include <stdio.h>
#include <stdlib.h>
#include <stdint.h>
#include "alignment_simd.h"
/*
* #define DEBUG_SIMD
*/
#ifdef __AVX512BW__
#include <immintrin.h>
#define EPU8_TYPE(ins) ins##_epu8
#define EPI8_TYPE(ins) ins##_epi8
#define EPI8_MASK_TYPE(ins) ins##_epi8_mask
#define EPI16_TYPE(ins) ins##_epi16
#define EPI16_MASK_TYPE(ins) ins##_epi16_mask
#define EPI32_TYPE(ins) ins##_epi32
#define EPI32_MASK_TYPE(ins) ins##_epi32_mask
#define EPI64_TYPE(ins) ins##_epi64
#define EPI64_MASK_TYPE(ins) ins##_epi64_mask
#define EPI128_TYPE(ins) ins##_epi128
#define SI512_TYPE(ins) ins##_si512
#define VTYPE512 __m512i
/* data conversion union */
typedef union __attribute__((packed, aligned (64))) {
VTYPE512 v;
/* __uint128_t u128[sizeof(VTYPE512)/sizeof(__uint128_t)];*/
/* [FIXME] not availaible on some compilers (e.g. gcc < 4.4 ; clang ?? ; icc ?? ; ) */
uint64_t u64[sizeof(VTYPE512)/sizeof(uint64_t)];
uint32_t u32[sizeof(VTYPE512)/sizeof(uint32_t)];
uint16_t u16[sizeof(VTYPE512)/sizeof(uint16_t)];
} vector512_t;
#endif
#ifdef __AVX2__
#include <immintrin.h>
#define EPU8_TYPE(ins) ins##_epu8
#define EPI8_TYPE(ins) ins##_epi8
#define EPI16_TYPE(ins) ins##_epi16
#define EPI32_TYPE(ins) ins##_epi32
#define EPI64_TYPE(ins) ins##_epi64
#define SI256_TYPE(ins) ins##_si256
#define VTYPE256 __m256i
/* data conversion union */
typedef union __attribute__((packed, aligned (32))) {
VTYPE256 v;
/* __uint128_t u128[sizeof(VTYPE256)/sizeof(__uint128_t)];*/
/* [FIXME] not availaible on some compilers (e.g. gcc < 4.4 ; clang ?? ; icc ?? ; ) */
uint64_t u64[sizeof(VTYPE256)/sizeof(uint64_t)];
uint32_t u32[sizeof(VTYPE256)/sizeof(uint32_t)];
uint16_t u16[sizeof(VTYPE256)/sizeof(uint16_t)];
} vector256_t;
#endif
#ifdef __SSE2__
#include <emmintrin.h>
#define EPU8_TYPE(ins) ins##_epu8
#define EPI8_TYPE(ins) ins##_epi8
#define EPI16_TYPE(ins) ins##_epi16
#define EPI32_TYPE(ins) ins##_epi32
#define EPI64_TYPE(ins) ins##_epi64
#define EPI64X_TYPE(ins) ins##_epi64x
#define SI128_TYPE(ins) ins##_si128
#define VTYPE128 __m128i
/* data conversion union */
typedef union __attribute__((packed, aligned (16))) {
VTYPE128 v;
/* __uint128_t u128[sizeof(VTYPE128)/sizeof(__uint128_t)];*/
/* [FIXME] not availaible on some compilers (e.g. gcc < 4.4 ; clang ?? ; icc ?? ; ) */
uint64_t u64[sizeof(VTYPE128)/sizeof(uint64_t)];
uint32_t u32[sizeof(VTYPE128)/sizeof(uint32_t)];
uint16_t u16[sizeof(VTYPE128)/sizeof(uint16_t)];
} vector128_t;
#endif
#ifdef __SSE__
#include <xmmintrin.h>
#define PU8_TYPE(ins) ins##_pu8
#define PI8_TYPE(ins) ins##_pi8
#define PI16_TYPE(ins) ins##_pi16
#define PI32_TYPE(ins) ins##_pi32
#define SI64_TYPE(ins) ins##_si64
#define VTYPE64 __m64
/* data conversion union */
typedef union __attribute__((packed, aligned (16))) {
VTYPE64 v;
uint64_t u64[sizeof(VTYPE64)/sizeof(uint64_t)];
uint32_t u32[sizeof(VTYPE64)/sizeof(uint32_t)];
uint16_t u16[sizeof(VTYPE64)/sizeof(uint16_t)];
} vector64_t;
#endif
/*
* check if the cpu has this instruction set with cpuid
*/
int alignment_avx512bw__compatible_proc() {
#if defined(__x86_64__)
uint64_t _ax = 0, _bx = 0, _cx = 0, _dx = 0;
asm volatile (
"pushq %%rbx" "\n\t"
"cpuid" "\n\t"
"movq %%rbx,%1" "\n\t"
"popq %%rbx" "\n\t"
: "=a" (_ax), "=r" (_bx), "=c" (_cx), "=d" (_dx)
: "a" (7), "c" (0)
);
#ifdef DEBUG_SIMD
fprintf(stderr,"[compatible avx512bw ? %s]\n", _bx & 1<<30 ? "yes":"no");
#endif
return (_bx & 1<<30) != 0;
#else
#ifdef DEBUG_SIMD
fprintf(stderr,"[compatible avx512bw ? no (32bits compiled)]\n");
#endif
return 0;
#endif
}
int alignment_avx2__compatible_proc() {
#if defined(__x86_64__)
uint64_t _ax = 0, _bx = 0, _cx = 0, _dx = 0;
asm volatile (
"pushq %%rbx" "\n\t"
"cpuid" "\n\t"
"movq %%rbx,%1" "\n\t"
"popq %%rbx" "\n\t"
: "=a" (_ax), "=r" (_bx), "=c" (_cx), "=d" (_dx)
: "a" (7), "c" (0)
);
#ifdef DEBUG_SIMD
fprintf(stderr,"[compatible avx2 ? %s]\n", _bx & 1<<5 ? "yes":"no");
#endif
return (_bx & 1<<5) != 0;
#else
#ifdef DEBUG_SIMD
fprintf(stderr,"[compatible avx2 ? no (32bits compiled)]\n");
#endif
return 0;
#endif
}
int alignment_sse2__compatible_proc() {
#if defined(__x86_64__)
uint64_t _ax = 0, _bx = 0, _cx = 0, _dx = 0;
asm volatile (
"pushq %%rbx" "\n\t"
"cpuid" "\n\t"
"movq %%rbx,%1" "\n\t"
"popq %%rbx" "\n\t"
: "=a" (_ax), "=r" (_bx), "=c" (_cx), "=d" (_dx)
: "a" (1)
);
#else
uint32_t _ax = 0, _bx = 0, _cx = 0, _dx = 0;
asm volatile (
"pushl %%ebx" "\n\t"
"cpuid" "\n\t"
"movl %%ebx,%1" "\n\t"
"popl %%ebx" "\n\t"
: "=a" (_ax), "=r" (_bx), "=c" (_cx), "=d" (_dx)
: "a" (1)
);
#endif
#ifdef DEBUG_SIMD
fprintf(stderr,"[compatible sse2 ? %s]\n", _dx & 1<<26 ? "yes":"no");
#endif
return (_dx & 1<<26) != 0;
}
int alignment_sse__compatible_proc() {
#if defined(__x86_64__)
uint64_t _ax = 0, _bx = 0, _cx = 0, _dx = 0;
asm volatile (
"pushq %%rbx" "\n\t"
"cpuid" "\n\t"
"movq %%rbx,%1" "\n\t"
"popq %%rbx" "\n\t"
: "=a" (_ax), "=r" (_bx), "=c" (_cx), "=d" (_dx)
: "a" (1)
);
#else
uint32_t _ax = 0, _bx = 0, _cx = 0, _dx = 0;
asm volatile (
"pushl %%ebx" "\n\t"
"cpuid" "\n\t"
"movl %%ebx,%1" "\n\t"
"popl %%ebx" "\n\t"
: "=a" (_ax), "=r" (_bx), "=c" (_cx), "=d" (_dx)
: "a" (1)
);
#endif
#ifdef DEBUG_SIMD
fprintf(stderr,"[compatible sse ? %s]\n", _dx & 1<<25 ? "yes":"no");
#endif
return (_dx & 1<<25) != 0;
}
/*
* macros and global variables (no need to export because not usefull ouside this .c file)
*/
/* avx512bw macros */
#ifdef __AVX512BW__
#define NEXTREADSEQ_TRIA512(inout_byte,inout_nbnuc, \
inout_vector,out_vtype_vLA) { \
if (!inout_nbnuc) { \
inout_vector.v = EPI16_TYPE(_mm512_set1)(*((uint16_t *)(inout_byte))); \
inout_nbnuc = 8; \
inout_byte += 2; \
} \
out_vtype_vLA = SI512_TYPE(_mm512_and)(inout_vector.v,vBufferMask512); \
inout_vector.v = EPI16_TYPE(_mm512_srli)(inout_vector.v,2); \
inout_nbnuc--; \
}
#define NEXTREADSEQ_HEXA512(inout_byte,inout_nbnuc, \
inout_vector,out_vtype_vLA) { \
if (!inout_nbnuc) { \
inout_vector.v = EPI32_TYPE(_mm512_set1)(*((uint32_t *)(inout_byte))); \
inout_nbnuc = 16; \
inout_byte += 4; \
} \
out_vtype_vLA = SI512_TYPE(_mm512_and)(inout_vector.v,vBufferMask512); \
inout_vector.v = EPI32_TYPE(_mm512_srli)(inout_vector.v,2); \
inout_nbnuc--; \
}
#define NEXTREADSEQ_OCTA512(inout_byte,inout_nbnuc, \
inout_vector,out_vtype_vLA) { \
if (!inout_nbnuc) { \
inout_vector.v = EPI64_TYPE(_mm512_set1)(*((uint64_t *)(inout_byte))); \
inout_nbnuc = 32; \
inout_byte += 8; \
} \
out_vtype_vLA = SI512_TYPE(_mm512_and)(inout_vector.v,vBufferMask512); \
inout_vector.v = EPI64_TYPE(_mm512_srli)(inout_vector.v,2); \
inout_nbnuc--; \
}
#define NEXTREADSEQ_QUAD512(inout_byte,inout_nbnuc, \
inout_vector,out_vtype_vLA) { \
if (!inout_nbnuc) { \
inout_vector.v = EPI64_TYPE(_mm512_set1)(*((uint64_t *)(inout_byte))); \
inout_nbnuc = 32; \
inout_byte += 8; \
} \
out_vtype_vLA = SI512_TYPE(_mm512_and)(inout_vector.v,vBufferMask512); \
inout_vector.v = EPI64_TYPE(_mm512_srli)(inout_vector.v,2); \
inout_nbnuc--; \
}
#define NEXTGENOSEQ_TRIA512(inout_subpos,inout_byte, \
inout_nbnuc_vector,inout_vector,out_vtype_vLB) { \
__mmask32 __u__; \
__u__ = EPI16_MASK_TYPE(_mm512_cmpeq)(inout_nbnuc_vector.v,SI512_TYPE(_mm512_setzero)()); \
if (__u__) { \
__mmask32 __d__; \
for (__d__ = 0; __d__ < 32; __d__++) { \
if (__u__ & 1 << (__d__)) { \
uint16_t i_nuc = *((uint16_t *)(inout_byte[__d__])); \
uint16_t i_nbnuc = 8; \
if (inout_subpos[__d__]) { \
i_nuc >>= inout_subpos[__d__] << 1; \
i_nbnuc -= inout_subpos[__d__]; \
inout_subpos[__d__] = 0; \
} \
inout_vector.v = EPI16_TYPE(_mm512_mask_set1)(inout_vector.v, 1 << (__d__), i_nuc); \
inout_nbnuc_vector.v = EPI16_TYPE(_mm512_mask_set1)(inout_nbnuc_vector.v, 1 << (__d__), i_nbnuc); \
inout_byte[__d__] += 2; \
} \
} \
} \
out_vtype_vLB = SI512_TYPE(_mm512_and)(inout_vector.v,vBufferMask512); \
inout_vector.v = EPI16_TYPE(_mm512_srli)(inout_vector.v,2); \
inout_nbnuc_vector.v = EPI16_TYPE(_mm512_sub)(inout_nbnuc_vector.v,vOnes512); \
}
#define NEXTGENOSEQ_HEXA512(inout_subpos,inout_byte, \
inout_nbnuc_vector,inout_vector,out_vtype_vLB) { \
__mmask16 __u__; \
__u__ = EPI32_MASK_TYPE(_mm512_cmpeq)(inout_nbnuc_vector.v,SI512_TYPE(_mm512_setzero)()); \
if (__u__) { \
__mmask16 __d__; \
for (__d__ = 0; __d__ < 16; __d__++) { \
if (__u__ & 1 << (__d__)) { \
uint32_t i_nuc = *((uint32_t *)(inout_byte[__d__])); \
uint32_t i_nbnuc = 16; \
if (inout_subpos[__d__]) { \
i_nuc >>= inout_subpos[__d__] << 1; \
i_nbnuc -= inout_subpos[__d__]; \
inout_subpos[__d__] = 0; \
} \
inout_vector.v = EPI32_TYPE(_mm512_mask_set1)(inout_vector.v, 1 << (__d__), i_nuc); \
inout_nbnuc_vector.v = EPI32_TYPE(_mm512_mask_set1)(inout_nbnuc_vector.v, 1 << (__d__), i_nbnuc); \
inout_byte[__d__] += 4; \
} \
} \
} \
out_vtype_vLB = SI512_TYPE(_mm512_and)(inout_vector.v,vBufferMask512); \
inout_vector.v = EPI32_TYPE(_mm512_srli)(inout_vector.v,2); \
inout_nbnuc_vector.v = EPI32_TYPE(_mm512_sub)(inout_nbnuc_vector.v,vOnes512); \
}
#define NEXTGENOSEQ_OCTA512(inout_subpos,inout_byte, \
inout_nbnuc_vector,inout_vector,out_vtype_vLB) { \
__mmask8 __u__; \
__u__ = EPI64_MASK_TYPE(_mm512_cmpeq)(inout_nbnuc_vector.v,SI512_TYPE(_mm512_setzero)()); \
if (__u__) { \
__mmask8 __d__; \
for (__d__ = 0; __d__ < 8; __d__++) { \
if (__u__ & 1 << (__d__)) { \
uint64_t i_nuc = *((uint64_t *)(inout_byte[__d__])); \
uint64_t i_nbnuc = 32; \
if (inout_subpos[__d__]) { \
i_nuc >>= inout_subpos[__d__] << 1; \
i_nbnuc -= inout_subpos[__d__]; \
inout_subpos[__d__] = 0; \
} \
inout_vector.v = EPI64_TYPE(_mm512_mask_set1)(inout_vector.v, 1 << (__d__), i_nuc); \
inout_nbnuc_vector.v = EPI64_TYPE(_mm512_mask_set1)(inout_nbnuc_vector.v, 1 << (__d__), i_nbnuc); \
inout_byte[__d__] += 8; \
} \
} \
} \
out_vtype_vLB = SI512_TYPE(_mm512_and)(inout_vector.v,vBufferMask512); \
inout_vector.v = EPI64_TYPE(_mm512_srli)(inout_vector.v,2); \
inout_nbnuc_vector.v = EPI64_TYPE(_mm512_sub)(inout_nbnuc_vector.v,vOnes512); \
}
#define NEXTGENOSEQ_QUAD512(inout_subpos,inout_byte, \
inout_nbnuc_vector,inout_vector,out_vtype_vLB) { \
__mmask8 __u__; \
__u__ = EPI64_MASK_TYPE(_mm512_cmpeq)(inout_nbnuc_vector.v,SI512_TYPE(_mm512_setzero)()); \
if (__u__) { \
__mmask8 __d__; \
for (__d__ = 0; __d__ < 4; __d__++) { \
if (__u__ & 3 << (2*__d__)) { \
uint64_t i_nuc = *((uint64_t *)(inout_byte[__d__])); \
uint64_t i_nbnuc = 32; \
if (inout_subpos[__d__]) { \
i_nuc >>= inout_subpos[__d__] << 1; \
i_nbnuc -= inout_subpos[__d__]; \
inout_subpos[__d__] = 0; \
} \
inout_vector.v = EPI64_TYPE(_mm512_mask_set1)(inout_vector.v, 3 << (2*__d__), i_nuc); \
inout_nbnuc_vector.v = EPI64_TYPE(_mm512_mask_set1)(inout_nbnuc_vector.v, 3 << (2*__d__), i_nbnuc); \
inout_byte[__d__] += 8; \
} \
} \
} \
out_vtype_vLB = SI512_TYPE(_mm512_and)(inout_vector.v,vBufferMask512); \
inout_vector.v = EPI64_TYPE(_mm512_srli)(inout_vector.v,2); \
inout_nbnuc_vector.v = EPI64_TYPE(_mm512_sub)(inout_nbnuc_vector.v,vOnes512); \
}
#define NEXTGENOSEQ_NOSUB_TRIA512(inout_byte, \
inout_nbnuc_vector,inout_vector,out_vtype_vLB) { \
__mmask32 __u__; \
__u__ = EPI16_MASK_TYPE(_mm512_cmpeq)(inout_nbnuc_vector.v,SI512_TYPE(_mm512_setzero)()); \
if (__u__) { \
__mmask32 __d__; \
for (__d__ = 0; __d__ < 32; __d__++) { \
if (__u__ & 1 << (__d__)) { \
uint16_t i_nuc = *((uint16_t *)(inout_byte[__d__])); \
uint16_t i_nbnuc = 8; \
inout_vector.v = EPI16_TYPE(_mm512_mask_set1)(inout_vector.v, 1 << (__d__), i_nuc); \
inout_nbnuc_vector.v = EPI16_TYPE(_mm512_mask_set1)(inout_nbnuc_vector.v, 1 << (__d__), i_nbnuc); \
inout_byte[__d__] += 2; \
} \
} \
} \
out_vtype_vLB = SI512_TYPE(_mm512_and)(inout_vector.v,vBufferMask512); \
inout_vector.v = EPI16_TYPE(_mm512_srli)(inout_vector.v,2); \
inout_nbnuc_vector.v = EPI16_TYPE(_mm512_sub)(inout_nbnuc_vector.v,vOnes512); \
}
#define NEXTGENOSEQ_NOSUB_HEXA512(inout_byte, \
inout_nbnuc_vector,inout_vector,out_vtype_vLB) { \
__mmask16 __u__; \
__u__ = EPI32_MASK_TYPE(_mm512_cmpeq)(inout_nbnuc_vector.v,SI512_TYPE(_mm512_setzero)()); \
if (__u__) { \
__mmask16 __d__; \
for (__d__ = 0; __d__ < 16; __d__++) { \
if (__u__ & 1 << (__d__)) { \
uint32_t i_nuc = *((uint32_t *)(inout_byte[__d__])); \
uint32_t i_nbnuc = 16; \
inout_vector.v = EPI32_TYPE(_mm512_mask_set1)(inout_vector.v, 1 << (__d__), i_nuc); \
inout_nbnuc_vector.v = EPI32_TYPE(_mm512_mask_set1)(inout_nbnuc_vector.v, 1 << (__d__), i_nbnuc); \
inout_byte[__d__] += 4; \
} \
} \
} \
out_vtype_vLB = SI512_TYPE(_mm512_and)(inout_vector.v,vBufferMask512); \
inout_vector.v = EPI32_TYPE(_mm512_srli)(inout_vector.v,2); \
inout_nbnuc_vector.v = EPI32_TYPE(_mm512_sub)(inout_nbnuc_vector.v,vOnes512); \
}
#define NEXTGENOSEQ_NOSUB_OCTA512(inout_byte, \
inout_nbnuc_vector,inout_vector,out_vtype_vLB) { \
__mmask8 __u__; \
__u__ = EPI64_MASK_TYPE(_mm512_cmpeq)(inout_nbnuc_vector.v,SI512_TYPE(_mm512_setzero)()); \
if (__u__) { \
__mmask8 __d__; \
for (__d__ = 0; __d__ < 8; __d__++) { \
if (__u__ & 1 << (__d__)) { \
uint64_t i_nuc = *((uint64_t *)(inout_byte[__d__])); \
uint64_t i_nbnuc = 32; \
inout_vector.v = EPI64_TYPE(_mm512_mask_set1)(inout_vector.v, 1 << (__d__), i_nuc); \
inout_nbnuc_vector.v = EPI64_TYPE(_mm512_mask_set1)(inout_nbnuc_vector.v, 1 << (__d__), i_nbnuc); \
inout_byte[__d__] += 8; \
} \
} \
} \
out_vtype_vLB = SI512_TYPE(_mm512_and)(inout_vector.v,vBufferMask512); \
inout_vector.v = EPI64_TYPE(_mm512_srli)(inout_vector.v,2); \
inout_nbnuc_vector.v = EPI64_TYPE(_mm512_sub)(inout_nbnuc_vector.v,vOnes512); \
}
#define NEXTGENOSEQ_NOSUB_QUAD512(inout_byte, \
inout_nbnuc_vector,inout_vector,out_vtype_vLB) { \
__mmask8 __u__; \
__u__ = EPI64_MASK_TYPE(_mm512_cmpeq)(inout_nbnuc_vector.v,SI512_TYPE(_mm512_setzero)()); \
if (__u__) { \
__mmask8 __d__; \
for (__d__ = 0; __d__ < 4; __d__++) { \
if (__u__ & 3 << (2*__d__)) { \
uint64_t i_nuc = *((uint64_t *)(inout_byte[__d__])); \
uint64_t i_nbnuc = 32; \
inout_vector.v = EPI64_TYPE(_mm512_mask_set1)(inout_vector.v, 3 << (2*__d__), i_nuc); \
inout_nbnuc_vector.v = EPI64_TYPE(_mm512_mask_set1)(inout_nbnuc_vector.v, 3 << (2*__d__), i_nbnuc); \
inout_byte[__d__] += 8; \
} \
} \
} \
out_vtype_vLB = SI512_TYPE(_mm512_and)(inout_vector.v,vBufferMask512); \
inout_vector.v = EPI64_TYPE(_mm512_srli)(inout_vector.v,2); \
inout_nbnuc_vector.v = EPI64_TYPE(_mm512_sub)(inout_nbnuc_vector.v,vOnes512); \
}
#define NEXTGENOSEQ_NOSUB_NOUP_TRIA512(inout_nbnuc_vector,inout_vector,out_vtype_vLB) { \
out_vtype_vLB = SI512_TYPE(_mm512_and)(inout_vector.v,vBufferMask512); \
inout_vector.v = EPI16_TYPE(_mm512_srli)(inout_vector.v,2); \
inout_nbnuc_vector.v = EPI16_TYPE(_mm512_sub)(inout_nbnuc_vector.v,vOnes512); \
}
#define NEXTGENOSEQ_NOSUB_NOUP_HEXA512(inout_nbnuc_vector,inout_vector,out_vtype_vLB) { \
out_vtype_vLB = SI512_TYPE(_mm512_and)(inout_vector.v,vBufferMask512); \
inout_vector.v = EPI32_TYPE(_mm512_srli)(inout_vector.v,2); \
inout_nbnuc_vector.v = EPI32_TYPE(_mm512_sub)(inout_nbnuc_vector.v,vOnes512); \
}
#define NEXTGENOSEQ_NOSUB_NOUP_OCTA512(inout_nbnuc_vector,inout_vector,out_vtype_vLB) { \
out_vtype_vLB = SI512_TYPE(_mm512_and)(inout_vector.v,vBufferMask512); \
inout_vector.v = EPI64_TYPE(_mm512_srli)(inout_vector.v,2); \
inout_nbnuc_vector.v = EPI64_TYPE(_mm512_sub)(inout_nbnuc_vector.v,vOnes512); \
}
#define NEXTGENOSEQ_NOSUB_NOUP_QUAD512(inout_nbnuc_vector,inout_vector,out_vtype_vLB) { \
out_vtype_vLB = SI512_TYPE(_mm512_and)(inout_vector.v,vBufferMask512); \
inout_vector.v = EPI64_TYPE(_mm512_srli)(inout_vector.v,2); \
inout_nbnuc_vector.v = EPI64_TYPE(_mm512_sub)(inout_nbnuc_vector.v,vOnes512); \
}
VTYPE512 vThreshold512 __attribute__ ((aligned (64))),
vMatchS512 __attribute__ ((aligned (64))),
vMismatchS512 __attribute__ ((aligned (64))),
vIndelOpenS512 __attribute__ ((aligned (64))),
vIndelExtendsS512 __attribute__ ((aligned (64))),
vOnes512 __attribute__ ((aligned (64))),
vBufferMask512 __attribute__ ((aligned (64)));
__mmask64 *vMsk512 __attribute__ ((aligned (64)));
void *vMsk512unaligned = NULL;
void alignment_avx512bw__clean() {if (vMsk512unaligned){ free(vMsk512unaligned); vMsk512unaligned = NULL;}}
#endif
/* avx2 macros */
#ifdef __AVX2__
#define NEXTREADSEQ_HEXA256(inout_byte,inout_nbnuc, \
inout_vector,out_vtype_vLA) { \
if (!inout_nbnuc) { \
inout_vector.v = EPI16_TYPE(_mm256_set1)(*((uint16_t *)(inout_byte))); \
inout_nbnuc = 8; \
inout_byte += 2; \
} \
out_vtype_vLA = SI256_TYPE(_mm256_and)(inout_vector.v,vBufferMask256); \
inout_vector.v = EPI16_TYPE(_mm256_srli)(inout_vector.v,2); \
inout_nbnuc--; \
}
#define NEXTREADSEQ_OCTA256(inout_byte,inout_nbnuc, \
inout_vector,out_vtype_vLA) { \
if (!inout_nbnuc) { \
inout_vector.v = EPI32_TYPE(_mm256_set1)(*((uint32_t *)(inout_byte))); \
inout_nbnuc = 16; \
inout_byte += 4; \
} \
out_vtype_vLA = SI256_TYPE(_mm256_and)(inout_vector.v,vBufferMask256); \
inout_vector.v = EPI32_TYPE(_mm256_srli)(inout_vector.v,2); \
inout_nbnuc--; \
}
#define NEXTREADSEQ_QUAD256(inout_byte,inout_nbnuc, \
inout_vector,out_vtype_vLA) { \
if (!inout_nbnuc) { \
inout_vector.v = EPI64X_TYPE(_mm256_set1)(*((uint64_t *)(inout_byte))); \
inout_nbnuc = 32; \
inout_byte += 8; \
} \
out_vtype_vLA = SI256_TYPE(_mm256_and)(inout_vector.v,vBufferMask256); \
inout_vector.v = EPI64_TYPE(_mm256_srli)(inout_vector.v,2); \
inout_nbnuc--; \
}
#define NEXTREADSEQ_PAIR256(inout_byte,inout_nbnuc, \
inout_vector,out_vtype_vLA) { \
if (!inout_nbnuc) { \
inout_vector.v = EPI64X_TYPE(_mm256_set1)(*((uint64_t *)(inout_byte))); \
inout_nbnuc = 32; \
inout_byte += 8; \
} \
out_vtype_vLA = SI256_TYPE(_mm256_and)(inout_vector.v,vBufferMask256); \
inout_vector.v = EPI64_TYPE(_mm256_srli)(inout_vector.v,2); \
inout_nbnuc--; \
}
#define NEXTGENOSEQ_HEXA256(inout_subpos,inout_byte, \
inout_nbnuc_vector,inout_vector,out_vtype_vLB) { \
unsigned int __u__; \
__u__ = EPI8_TYPE(_mm256_movemask)(EPI16_TYPE(_mm256_cmpeq)(inout_nbnuc_vector.v,SI256_TYPE(_mm256_setzero)())); \
if (__u__) { \
unsigned int __d__; \
for (__d__ = 0; __d__ < 16; __d__++) { \
if (__u__ & 1 << (2*__d__)) { \
inout_vector.u16[__d__] = \
*((uint16_t *)(inout_byte[__d__])); \
inout_nbnuc_vector.u16[__d__] = 8; \
inout_byte[__d__] += 2; \
if (inout_subpos[__d__]) { \
inout_vector.u16[__d__] >>= inout_subpos[__d__] << 1; \
inout_nbnuc_vector.u16[__d__] -= inout_subpos[__d__]; \
inout_subpos[__d__] = 0; \
} \
} \
} \
} \
out_vtype_vLB = SI256_TYPE(_mm256_and)(inout_vector.v,vBufferMask256); \
inout_vector.v = EPI16_TYPE(_mm256_srli)(inout_vector.v,2); \
inout_nbnuc_vector.v = EPI16_TYPE(_mm256_sub)(inout_nbnuc_vector.v,vOnes256); \
}
#define NEXTGENOSEQ_OCTA256(inout_subpos,inout_byte, \
inout_nbnuc_vector,inout_vector,out_vtype_vLB) { \
unsigned int __u__; \
__u__ = _mm256_movemask_ps((__m256)EPI32_TYPE(_mm256_cmpeq)(inout_nbnuc_vector.v,SI256_TYPE(_mm256_setzero)())); \
if (__u__) { \
unsigned int __d__; \
for (__d__ = 0; __d__ < 8; __d__++) { \
if (__u__ & 1 << (__d__)) { \
inout_vector.u32[__d__] = \
*((uint32_t *)(inout_byte[__d__])); \
inout_nbnuc_vector.u32[__d__] = 16; \
inout_byte[__d__] += 4; \
if (inout_subpos[__d__]) { \
inout_vector.u32[__d__] >>= inout_subpos[__d__] << 1; \
inout_nbnuc_vector.u32[__d__] -= inout_subpos[__d__]; \
inout_subpos[__d__] = 0; \
} \
} \
} \
} \
out_vtype_vLB = SI256_TYPE(_mm256_and)(inout_vector.v,vBufferMask256); \
inout_vector.v = EPI32_TYPE(_mm256_srli)(inout_vector.v,2); \
inout_nbnuc_vector.v = EPI32_TYPE(_mm256_sub)(inout_nbnuc_vector.v,vOnes256); \
}
#define NEXTGENOSEQ_QUAD256(inout_subpos,inout_byte, \
inout_nbnuc_vector,inout_vector,out_vtype_vLB) { \
unsigned int __u__; \
__u__ = _mm256_movemask_pd((__m256d)EPI64_TYPE(_mm256_cmpeq)(inout_nbnuc_vector.v,SI256_TYPE(_mm256_setzero)())); \
if (__u__) { \
unsigned int __d__; \
for (__d__ = 0; __d__ < 4; __d__++) { \
if (__u__ & 1 << (__d__)) { \
inout_vector.u64[__d__] = \
*((uint64_t *)(inout_byte[__d__])); \
inout_nbnuc_vector.u64[__d__] = 32; \
inout_byte[__d__] += 8; \
if (inout_subpos[__d__]) { \
inout_vector.u64[__d__] >>= inout_subpos[__d__] << 1; \
inout_nbnuc_vector.u64[__d__] -= inout_subpos[__d__]; \
inout_subpos[__d__] = 0; \
} \
} \
} \
} \
out_vtype_vLB = SI256_TYPE(_mm256_and)(inout_vector.v,vBufferMask256); \
inout_vector.v = EPI64_TYPE(_mm256_srli)(inout_vector.v,2); \
inout_nbnuc_vector.v = EPI64_TYPE(_mm256_sub)(inout_nbnuc_vector.v,vOnes256); \
}
#define NEXTGENOSEQ_PAIR256(inout_subpos,inout_byte, \
inout_nbnuc_vector,inout_vector,out_vtype_vLB) { \
unsigned int __u__; \
__u__ = _mm256_movemask_pd((__m256d)EPI64_TYPE(_mm256_cmpeq)(inout_nbnuc_vector.v,SI256_TYPE(_mm256_setzero)())); \
if (__u__) { \
unsigned int __d__; \
for (__d__ = 0; __d__ < 2; __d__++) { \
if (__u__ & 1 << (2*__d__)) { \
inout_vector.u64[2*__d__] = \
*((uint64_t *)(inout_byte[__d__])); \
inout_nbnuc_vector.u64[2*__d__ ] = 32; \
inout_nbnuc_vector.u64[2*__d__ + 1] = 32; \
inout_byte[__d__] += 8; \
if (inout_subpos[__d__]) { \
inout_vector.u64[2*__d__] >>= inout_subpos[__d__] << 1; \
inout_nbnuc_vector.u64[2*__d__ ] -= inout_subpos[__d__]; \
inout_nbnuc_vector.u64[2*__d__ + 1] -= inout_subpos[__d__]; \
inout_subpos[__d__] = 0; \
} \
} \
} \
} \
out_vtype_vLB = SI256_TYPE(_mm256_and)(inout_vector.v,vBufferMask256); \
inout_vector.v = EPI64_TYPE(_mm256_srli)(inout_vector.v,2); \
inout_nbnuc_vector.v = EPI64_TYPE(_mm256_sub)(inout_nbnuc_vector.v,vOnes256); \
}
#define NEXTGENOSEQ_NOSUB_HEXA256(inout_byte, \
inout_nbnuc_vector,inout_vector,out_vtype_vLB) { \
unsigned int __u__; \
__u__ = EPI8_TYPE(_mm256_movemask)(EPI16_TYPE(_mm256_cmpeq)(inout_nbnuc_vector.v,SI256_TYPE(_mm256_setzero)())); \
if (__u__) { \
unsigned int __d__; \
for (__d__ = 0; __d__ < 16; __d__++) { \
if (__u__ & 1 << (2*__d__)) { \
inout_vector.u16[__d__] = \
*((uint16_t *)(inout_byte[__d__])); \
inout_nbnuc_vector.u16[__d__] = 8; \
inout_byte[__d__] += 2; \
} \
} \
} \
out_vtype_vLB = SI256_TYPE(_mm256_and)(inout_vector.v,vBufferMask256); \
inout_vector.v = EPI16_TYPE(_mm256_srli)(inout_vector.v,2); \
inout_nbnuc_vector.v = EPI16_TYPE(_mm256_sub)(inout_nbnuc_vector.v,vOnes256); \
}
#define NEXTGENOSEQ_NOSUB_OCTA256(inout_byte, \
inout_nbnuc_vector,inout_vector,out_vtype_vLB) { \
unsigned int __u__; \
__u__ = _mm256_movemask_ps((__m256)EPI32_TYPE(_mm256_cmpeq)(inout_nbnuc_vector.v,SI256_TYPE(_mm256_setzero)())); \
if (__u__) { \
unsigned int __d__; \
for (__d__ = 0; __d__ < 8; __d__++) { \
if (__u__ & 1 << (__d__)) { \
inout_vector.u32[__d__] = \
*((uint32_t *)(inout_byte[__d__])); \
inout_nbnuc_vector.u32[__d__] = 16; \
inout_byte[__d__] += 4; \
} \
} \
} \
out_vtype_vLB = SI256_TYPE(_mm256_and)(inout_vector.v,vBufferMask256); \
inout_vector.v = EPI32_TYPE(_mm256_srli)(inout_vector.v,2); \
inout_nbnuc_vector.v = EPI32_TYPE(_mm256_sub)(inout_nbnuc_vector.v,vOnes256); \
}
#define NEXTGENOSEQ_NOSUB_QUAD256(inout_byte, \
inout_nbnuc_vector,inout_vector,out_vtype_vLB) { \
unsigned int __u__; \
__u__ = _mm256_movemask_pd((__m256d)EPI64_TYPE(_mm256_cmpeq)(inout_nbnuc_vector.v,SI256_TYPE(_mm256_setzero)())); \
if (__u__) { \
unsigned int __d__; \
for (__d__ = 0; __d__ < 4; __d__++) { \
if (__u__ & 1 << (__d__)) { \
inout_vector.u64[__d__] = \
*((uint64_t *)(inout_byte[__d__])); \
inout_nbnuc_vector.u64[__d__] = 32; \
inout_byte[__d__] += 8; \
} \
} \
} \
out_vtype_vLB = SI256_TYPE(_mm256_and)(inout_vector.v,vBufferMask256); \
inout_vector.v = EPI64_TYPE(_mm256_srli)(inout_vector.v,2); \
inout_nbnuc_vector.v = EPI64_TYPE(_mm256_sub)(inout_nbnuc_vector.v,vOnes256); \
}
#define NEXTGENOSEQ_NOSUB_PAIR256(inout_byte, \
inout_nbnuc_vector,inout_vector,out_vtype_vLB) { \
unsigned int __u__; \
__u__ = _mm256_movemask_pd((__m256d)EPI64_TYPE(_mm256_cmpeq)(inout_nbnuc_vector.v,SI256_TYPE(_mm256_setzero)())); \
if (__u__) { \
unsigned int __d__; \
for (__d__ = 0; __d__ < 2; __d__++) { \
if (__u__ & 1 << (2*__d__)) { \
inout_vector.u64[2*__d__] = \
*((uint64_t *)(inout_byte[__d__])); \
inout_nbnuc_vector.u64[2*__d__ ] = 32; \
inout_nbnuc_vector.u64[2*__d__ + 1] = 32; \
inout_byte[__d__] += 8; \
} \
} \
} \
out_vtype_vLB = SI256_TYPE(_mm256_and)(inout_vector.v,vBufferMask256); \
inout_vector.v = EPI64_TYPE(_mm256_srli)(inout_vector.v,2); \
inout_nbnuc_vector.v = EPI64_TYPE(_mm256_sub)(inout_nbnuc_vector.v,vOnes256); \
}
#define NEXTGENOSEQ_NOSUB_NOUP_HEXA256(inout_nbnuc_vector,inout_vector,out_vtype_vLB) { \
out_vtype_vLB = SI256_TYPE(_mm256_and)(inout_vector.v,vBufferMask256); \
inout_vector.v = EPI16_TYPE(_mm256_srli)(inout_vector.v,2); \
inout_nbnuc_vector.v = EPI16_TYPE(_mm256_sub)(inout_nbnuc_vector.v,vOnes256); \
}
#define NEXTGENOSEQ_NOSUB_NOUP_OCTA256(inout_nbnuc_vector,inout_vector,out_vtype_vLB) { \
out_vtype_vLB = SI256_TYPE(_mm256_and)(inout_vector.v,vBufferMask256); \
inout_vector.v = EPI32_TYPE(_mm256_srli)(inout_vector.v,2); \
inout_nbnuc_vector.v = EPI32_TYPE(_mm256_sub)(inout_nbnuc_vector.v,vOnes256); \
}
#define NEXTGENOSEQ_NOSUB_NOUP_QUAD256(inout_nbnuc_vector,inout_vector,out_vtype_vLB) { \
out_vtype_vLB = SI256_TYPE(_mm256_and)(inout_vector.v,vBufferMask256); \
inout_vector.v = EPI64_TYPE(_mm256_srli)(inout_vector.v,2); \
inout_nbnuc_vector.v = EPI64_TYPE(_mm256_sub)(inout_nbnuc_vector.v,vOnes256); \
}
#define NEXTGENOSEQ_NOSUB_NOUP_PAIR256(inout_nbnuc_vector,inout_vector,out_vtype_vLB) { \
out_vtype_vLB = SI256_TYPE(_mm256_and)(inout_vector.v,vBufferMask256); \
inout_vector.v = EPI64_TYPE(_mm256_srli)(inout_vector.v,2); \
inout_nbnuc_vector.v = EPI64_TYPE(_mm256_sub)(inout_nbnuc_vector.v,vOnes256); \
}
VTYPE256 vThreshold256 __attribute__ ((aligned (32))),
vMatchS256 __attribute__ ((aligned (32))),
vMismatchS256 __attribute__ ((aligned (32))),
vIndelOpenS256 __attribute__ ((aligned (32))),
vIndelExtendsS256 __attribute__ ((aligned (32))),
vOnes256 __attribute__ ((aligned (32))),
vBufferMask256 __attribute__ ((aligned (32))),
*vMsk256 __attribute__ ((aligned (32)));
void *vMsk256unaligned = NULL;
void alignment_avx2__clean() {if (vMsk256unaligned){ free(vMsk256unaligned); vMsk256unaligned = NULL;}}
#endif
/* sse2 macros */
#ifdef __SSE2__
#define NEXTREADSEQ_OCTA128(inout_byte,inout_nbnuc, \
inout_vector,out_vtype_vLA) { \
if (!inout_nbnuc) { \
inout_vector.v = EPI16_TYPE(_mm_set1)(*(uint16_t *)(inout_byte)); \
inout_nbnuc = 8; \
inout_byte += 2; \
} \
out_vtype_vLA = SI128_TYPE(_mm_and)(inout_vector.v,vBufferMask128); \
inout_vector.v = EPI16_TYPE(_mm_srli)(inout_vector.v,2); \
inout_nbnuc--; \
}
#define NEXTREADSEQ_QUAD128(inout_byte,inout_nbnuc, \
inout_vector,out_vtype_vLA) { \
if (!inout_nbnuc) { \
inout_vector.v = EPI32_TYPE(_mm_set1)(*(uint32_t *)(inout_byte)); \
inout_nbnuc = 16; \
inout_byte += 4; \
} \
out_vtype_vLA = SI128_TYPE(_mm_and)(inout_vector.v,vBufferMask128); \
inout_vector.v = EPI32_TYPE(_mm_srli)(inout_vector.v,2); \
inout_nbnuc--; \
}
#define NEXTREADSEQ_PAIR128(inout_byte,inout_nbnuc, \
inout_vector,out_vtype_vLA) { \
if (!inout_nbnuc) { \
inout_vector.v = EPI64X_TYPE(_mm_set1)(*(uint64_t *)(inout_byte)); \
inout_nbnuc = 32; \
inout_byte += 8; \
} \
out_vtype_vLA = SI128_TYPE(_mm_and)(inout_vector.v,vBufferMask128); \
inout_vector.v = EPI64_TYPE(_mm_srli)(inout_vector.v,2); \
inout_nbnuc--; \
}
#define NEXTREADSEQ_MONO128(inout_byte, \
inout_nbnuc,inout_vector,out_vtype_vLA) { \
if (!inout_nbnuc) { \
inout_vector.v = EPI64X_TYPE(_mm_set1)(*(uint64_t *)(inout_byte)); \
inout_nbnuc = 32; \
inout_byte += 8; \
} \
out_vtype_vLA = SI128_TYPE(_mm_and)(inout_vector.v,vBufferMask128); \
inout_vector.v = EPI64_TYPE(_mm_srli)(inout_vector.v,2); \
inout_nbnuc--; \
}
#define NEXTGENOSEQ_OCTA128(inout_subpos,inout_byte, \
inout_nbnuc_vector,inout_vector,out_vtype_vLB) { \
unsigned int __u__; \
__u__ = EPI8_TYPE(_mm_movemask)(EPI16_TYPE(_mm_cmpeq)(inout_nbnuc_vector.v,SI128_TYPE(_mm_setzero)())); \
if (__u__) { \
unsigned int __d__; \
for (__d__ = 0; __d__ < 8; __d__++) { \
if (__u__ & 1 << (2*__d__)) { \
inout_vector.u16[__d__] = \
*((uint16_t *)(inout_byte[__d__])); \
inout_nbnuc_vector.u16[__d__] = 8; \
inout_byte[__d__] += 2; \
if (inout_subpos[__d__]) { \
inout_vector.u16[__d__] >>= inout_subpos[__d__] << 1; \
inout_nbnuc_vector.u16[__d__] -= inout_subpos[__d__]; \
inout_subpos[__d__] = 0; \
} \
} \
} \
} \
out_vtype_vLB = SI128_TYPE(_mm_and)(inout_vector.v,vBufferMask128); \
inout_vector.v = EPI16_TYPE(_mm_srli)(inout_vector.v,2); \
inout_nbnuc_vector.v = EPI16_TYPE(_mm_sub)(inout_nbnuc_vector.v,vOnes128); \
}
#define NEXTGENOSEQ_QUAD128(inout_subpos,inout_byte, \
inout_nbnuc_vector,inout_vector,out_vtype_vLB) { \
unsigned int __u__; \
__u__ = _mm_movemask_ps((__m128)EPI32_TYPE(_mm_cmpeq)(inout_nbnuc_vector.v,SI128_TYPE(_mm_setzero)())); \
if (__u__) { \
unsigned int __d__; \
for (__d__ = 0; __d__ < 4; __d__++) { \
if (__u__ & 1 << (__d__)) { \
inout_vector.u32[__d__] = \
*((uint32_t *)(inout_byte[__d__])); \
inout_nbnuc_vector.u32[__d__] = 16; \
inout_byte[__d__] += 4; \
if (inout_subpos[__d__]) { \
inout_vector.u32[__d__] >>= inout_subpos[__d__] << 1; \
inout_nbnuc_vector.u32[__d__] -= inout_subpos[__d__]; \
inout_subpos[__d__] = 0; \
} \
} \
} \
} \
out_vtype_vLB = SI128_TYPE(_mm_and)(inout_vector.v,vBufferMask128); \
inout_vector.v = EPI32_TYPE(_mm_srli)(inout_vector.v,2); \
inout_nbnuc_vector.v = EPI32_TYPE(_mm_sub)(inout_nbnuc_vector.v,vOnes128); \
}
#define NEXTGENOSEQ_PAIR128(inout_subpos,inout_byte, \
inout_nbnuc_vector,inout_vector,out_vtype_vLB) { \
unsigned int __u__; \
__u__ = _mm_movemask_pd((__m128d)EPI32_TYPE(_mm_cmpeq)(inout_nbnuc_vector.v,SI128_TYPE(_mm_setzero)())); \
if (__u__) { \
unsigned int __d__; \
for (__d__ = 0; __d__ < 2; __d__++) { \
if (__u__ & 1 << (__d__)) { \
inout_vector.u64[__d__] = \
*((uint64_t *)(inout_byte[__d__])); \
inout_nbnuc_vector.u32[2*__d__ ] = 32; \
inout_nbnuc_vector.u32[2*__d__ + 1] = 32; \
inout_byte[__d__] += 8; \
if (inout_subpos[__d__]) { \
inout_vector.u64[__d__] >>= inout_subpos[__d__] << 1; \
inout_nbnuc_vector.u32[2*__d__ ] -= inout_subpos[__d__]; \
inout_nbnuc_vector.u32[2*__d__ + 1] -= inout_subpos[__d__]; \
inout_subpos[__d__] = 0; \
} \
} \
} \
} \
out_vtype_vLB = SI128_TYPE(_mm_and)(inout_vector.v,vBufferMask128); \
inout_vector.v = EPI64_TYPE(_mm_srli)(inout_vector.v,2); \
inout_nbnuc_vector.v = EPI32_TYPE(_mm_sub)(inout_nbnuc_vector.v,vOnes128); \
}
#define NEXTGENOSEQ_MONO128(inout_subpos,inout_byte, \
inout_nbnuc,inout_vector,out_vtype_vLB) { \
if (!inout_nbnuc) { \
inout_vector.v = EPI64X_TYPE(_mm_set1)(*((uint64_t *)(inout_byte))); \
inout_nbnuc = 32; \
inout_byte += 8; \
if (inout_subpos) { \
inout_vector.v = EPI64_TYPE(_mm_srli)(inout_vector.v, inout_subpos << 1); \
inout_nbnuc -= inout_subpos; \
inout_subpos = 0; \
} \
} \
out_vtype_vLB = SI128_TYPE(_mm_and)(inout_vector.v,vBufferMask128); \
inout_vector.v = EPI64_TYPE(_mm_srli)(inout_vector.v,2); \
inout_nbnuc--; \
}
#define NEXTGENOSEQ_NOSUB_OCTA128(inout_byte, \
inout_nbnuc_vector,inout_vector,out_vtype_vLB) { \
unsigned int __u__; \
__u__ = EPI8_TYPE(_mm_movemask)(EPI16_TYPE(_mm_cmpeq)(inout_nbnuc_vector.v,SI128_TYPE(_mm_setzero)())); \
if (__u__) { \
unsigned int __d__; \
for (__d__ = 0; __d__ < 8; __d__++) { \
if (__u__ & 1 << (2*__d__)) { \
inout_vector.u16[__d__] = \
*((uint16_t *)(inout_byte[__d__])); \
inout_nbnuc_vector.u16[__d__] = 8; \
inout_byte[__d__] += 2; \
} \
} \
} \
out_vtype_vLB = SI128_TYPE(_mm_and)(inout_vector.v,vBufferMask128); \
inout_vector.v = EPI16_TYPE(_mm_srli)(inout_vector.v,2); \
inout_nbnuc_vector.v = EPI16_TYPE(_mm_sub)(inout_nbnuc_vector.v,vOnes128); \
}
#define NEXTGENOSEQ_NOSUB_QUAD128(inout_byte, \
inout_nbnuc_vector,inout_vector,out_vtype_vLB) { \
unsigned int __u__; \
__u__ = _mm_movemask_ps((__m128)EPI32_TYPE(_mm_cmpeq)(inout_nbnuc_vector.v,SI128_TYPE(_mm_setzero)())); \
if (__u__) { \
unsigned int __d__; \
for (__d__ = 0; __d__ < 4; __d__++) { \
if (__u__ & 1 << (__d__)) { \
inout_vector.u32[__d__] = \
*((uint32_t *)(inout_byte[__d__])); \
inout_nbnuc_vector.u32[__d__] = 16; \
inout_byte[__d__] += 4; \
} \
} \
} \
out_vtype_vLB = SI128_TYPE(_mm_and)(inout_vector.v,vBufferMask128); \
inout_vector.v = EPI32_TYPE(_mm_srli)(inout_vector.v,2); \
inout_nbnuc_vector.v = EPI32_TYPE(_mm_sub)(inout_nbnuc_vector.v,vOnes128); \
}
#define NEXTGENOSEQ_NOSUB_PAIR128(inout_byte, \
inout_nbnuc_vector,inout_vector,out_vtype_vLB) { \
unsigned int __u__; \
__u__ = _mm_movemask_pd((__m128d)EPI32_TYPE(_mm_cmpeq)(inout_nbnuc_vector.v,SI128_TYPE(_mm_setzero)())); \
if (__u__) { \
unsigned int __d__; \
for (__d__ = 0; __d__ < 2; __d__++) { \
if (__u__ & 1 << (__d__)) { \
inout_vector.u64[__d__] = \
*((uint64_t *)(inout_byte[__d__])); \
inout_nbnuc_vector.u32[2*__d__ ] = 32; \
inout_nbnuc_vector.u32[2*__d__ + 1] = 32; \
inout_byte[__d__] += 8; \
} \
} \
} \
out_vtype_vLB = SI128_TYPE(_mm_and)(inout_vector.v,vBufferMask128); \
inout_vector.v = EPI64_TYPE(_mm_srli)(inout_vector.v,2); \
inout_nbnuc_vector.v = EPI32_TYPE(_mm_sub)(inout_nbnuc_vector.v,vOnes128); \
}
#define NEXTGENOSEQ_NOSUB_MONO128(inout_byte, \
inout_nbnuc,inout_vector,out_vtype_vLB) { \
if (!inout_nbnuc) { \
inout_vector.v = EPI64X_TYPE(_mm_set1)(*((uint64_t *)(inout_byte))); \
inout_nbnuc = 32; \