DESCRIPTION

Package: posologyr
Title: Individual Dose Optimization using Population Pharmacokinetics
Version: 1.2.7
Authors@R: c(
    person("Cyril","Leven",role = c("aut", "cre","cph"),
           email = "cyril.leven@chu-brest.fr",
           comment = c(ORCID = "0000-0002-0697-4370")),
    person("Matthew","Fidler",role = c("ctb"),
           email="matthew.fidler@gmail.com",
           comment = c(ORCID = "0000-0001-8538-6691")),
    person("Emmanuelle","Comets",role = c("ctb")),
    person("Audrey","Lavenu",role = c("ctb")),
    person("Marc","Lavielle",role = c("ctb"))
    )
Description: Optimize drug regimens through model-informed precision dosing, 
    using individual pharmacokinetic (PK) and pharmacokinetic-pharmacodynamic 
    (PK-PD) profiles. By integrating therapeutic drug monitoring (TDM) data with
    population models, 'posologyr' provides accurate posterior estimates and 
    enables the calculation of personalized dosing regimens. The empirical Bayes
    estimates are computed following the method described by Kang et al. (2012) 
    <doi:10.4196/kjpp.2012.16.2.97>.
License: AGPL-3
Encoding: UTF-8
Roxygen: list(markdown = TRUE)
RoxygenNote: 7.3.2
Depends:
    R (>= 3.5.0)
Imports:
    rxode2,
    stats,
    mvtnorm,
    data.table
Suggests:
    lotri,
    rmarkdown,
    testthat (>= 3.0.0),
    ggplot2,
    magrittr,
    tidyr
URL: https://levenc.github.io/posologyr/, https://github.com/levenc/posologyr
BugReports: https://github.com/levenc/posologyr/issues
Config/testthat/edition: 3