diff --git a/clang/lib/Format/UnwrappedLineParser.cpp b/clang/lib/Format/UnwrappedLineParser.cpp
index d84914c6a4cf1c..8f6453a25d9d41 100644
--- a/clang/lib/Format/UnwrappedLineParser.cpp
+++ b/clang/lib/Format/UnwrappedLineParser.cpp
@@ -2518,7 +2518,7 @@ bool UnwrappedLineParser::parseParens(TokenType AmpAmpTokenType) {
         parseChildBlock();
       break;
     case tok::r_paren:
-      if (!MightBeStmtExpr &&
+      if (!MightBeStmtExpr && !Line->InMacroBody &&
           Style.RemoveParentheses > FormatStyle::RPS_Leave) {
         const auto *Prev = LeftParen->Previous;
         const auto *Next = Tokens->peekNextToken();
diff --git a/clang/unittests/Format/FormatTest.cpp b/clang/unittests/Format/FormatTest.cpp
index 7b65c8d6e21b00..13937a15fdaee2 100644
--- a/clang/unittests/Format/FormatTest.cpp
+++ b/clang/unittests/Format/FormatTest.cpp
@@ -26972,6 +26972,7 @@ TEST_F(FormatTest, RemoveParentheses) {
   EXPECT_EQ(Style.RemoveParentheses, FormatStyle::RPS_Leave);
 
   Style.RemoveParentheses = FormatStyle::RPS_MultipleParentheses;
+  verifyFormat("#define Foo(...) foo((__VA_ARGS__))", Style);
   verifyFormat("int x __attribute__((aligned(16))) = 0;", Style);
   verifyFormat("decltype((foo->bar)) baz;", Style);
   verifyFormat("class __declspec(dllimport) X {};",
@@ -27006,6 +27007,7 @@ TEST_F(FormatTest, RemoveParentheses) {
   verifyFormat("return (({ 0; }));", "return ((({ 0; })));", Style);
 
   Style.RemoveParentheses = FormatStyle::RPS_ReturnStatement;
+  verifyFormat("#define Return0 return (0);", Style);
   verifyFormat("return 0;", "return (0);", Style);
   verifyFormat("co_return 0;", "co_return ((0));", Style);
   verifyFormat("return 0;", "return (((0)));", Style);