diff --git a/clang/lib/CodeGen/CGStmt.cpp b/clang/lib/CodeGen/CGStmt.cpp
index 7158a06e6bc3b3..b138c87a853495 100644
--- a/clang/lib/CodeGen/CGStmt.cpp
+++ b/clang/lib/CodeGen/CGStmt.cpp
@@ -752,7 +752,7 @@ void CodeGenFunction::EmitAttributedStmt(const AttributedStmt &S) {
     } break;
     case attr::CXXAssume: {
       const Expr *Assumption = cast<CXXAssumeAttr>(A)->getAssumption();
-      if (getLangOpts().CXXAssumptions &&
+      if (getLangOpts().CXXAssumptions && Builder.GetInsertBlock() &&
           !Assumption->HasSideEffects(getContext())) {
         llvm::Value *AssumptionVal = EvaluateExprAsBool(Assumption);
         Builder.CreateAssumption(AssumptionVal);
diff --git a/clang/test/SemaCXX/cxx23-assume.cpp b/clang/test/SemaCXX/cxx23-assume.cpp
index 9138501d726dd6..eeae59daea3f70 100644
--- a/clang/test/SemaCXX/cxx23-assume.cpp
+++ b/clang/test/SemaCXX/cxx23-assume.cpp
@@ -158,3 +158,12 @@ foo (int x, int y)
   return x + y;
 }
 }
+
+// Do not crash when assumptions are unreachable.
+namespace gh106898 {
+int foo () { 
+    while(1);
+    int a = 0, b = 1;
+    __attribute__((assume (a < b)));
+}
+}