diff --git a/res/css/views/elements/_AccessibleButton.scss b/res/css/views/elements/_AccessibleButton.scss
index 021e8ffc8c1..a6fb0a7e22b 100644
--- a/res/css/views/elements/_AccessibleButton.scss
+++ b/res/css/views/elements/_AccessibleButton.scss
@@ -18,7 +18,7 @@ limitations under the License.
     cursor: pointer;
 
     &.mx_AccessibleButton_disabled {
-        cursor: default;
+        cursor: not-allowed;
 
         &.mx_AccessibleButton_kind_primary,
         &.mx_AccessibleButton_kind_primary_outline,
diff --git a/src/components/structures/RoomView.tsx b/src/components/structures/RoomView.tsx
index ed5f60d3572..b0f3341e7af 100644
--- a/src/components/structures/RoomView.tsx
+++ b/src/components/structures/RoomView.tsx
@@ -168,6 +168,7 @@ export interface IRoomState {
     searchInProgress?: boolean;
     callState?: CallState;
     canPeek: boolean;
+    canSelfRedact: boolean;
     showApps: boolean;
     isPeeking: boolean;
     showRightPanel: boolean;
@@ -251,6 +252,7 @@ export class RoomView extends React.Component<IRoomProps, IRoomState> {
             searchResults: null,
             callState: null,
             canPeek: false,
+            canSelfRedact: false,
             showApps: false,
             isPeeking: false,
             showRightPanel: false,
@@ -1165,10 +1167,14 @@ export class RoomView extends React.Component<IRoomProps, IRoomState> {
     private updatePermissions(room: Room) {
         if (room) {
             const me = this.context.getUserId();
-            const canReact = room.getMyMembership() === "join" && room.currentState.maySendEvent("m.reaction", me);
+            const canReact = (
+                room.getMyMembership() === "join" &&
+                room.currentState.maySendEvent(EventType.Reaction, me)
+            );
             const canSendMessages = room.maySendMessage();
+            const canSelfRedact = room.currentState.maySendEvent(EventType.RoomRedaction, me);
 
-            this.setState({ canReact, canSendMessages });
+            this.setState({ canReact, canSendMessages, canSelfRedact });
         }
     }
 
diff --git a/src/components/views/emojipicker/Category.tsx b/src/components/views/emojipicker/Category.tsx
index d4ea4e89ffb..45ed7144e0d 100644
--- a/src/components/views/emojipicker/Category.tsx
+++ b/src/components/views/emojipicker/Category.tsx
@@ -45,6 +45,7 @@ interface IProps {
     onClick(emoji: IEmoji): void;
     onMouseEnter(emoji: IEmoji): void;
     onMouseLeave(emoji: IEmoji): void;
+    isEmojiDisabled?: (unicode: string) => boolean;
 }
 
 class Category extends React.PureComponent<IProps> {
@@ -60,6 +61,7 @@ class Category extends React.PureComponent<IProps> {
                     onClick={onClick}
                     onMouseEnter={onMouseEnter}
                     onMouseLeave={onMouseLeave}
+                    disabled={this.props.isEmojiDisabled?.(emoji.unicode)}
                 />
             ))
         }</div>);
diff --git a/src/components/views/emojipicker/Emoji.tsx b/src/components/views/emojipicker/Emoji.tsx
index 91eada12b36..e36bd9ff5c7 100644
--- a/src/components/views/emojipicker/Emoji.tsx
+++ b/src/components/views/emojipicker/Emoji.tsx
@@ -26,6 +26,7 @@ interface IProps {
     onClick(emoji: IEmoji): void;
     onMouseEnter(emoji: IEmoji): void;
     onMouseLeave(emoji: IEmoji): void;
+    disabled?: boolean;
 }
 
 class Emoji extends React.PureComponent<IProps> {
@@ -40,6 +41,7 @@ class Emoji extends React.PureComponent<IProps> {
                 onMouseLeave={() => onMouseLeave(emoji)}
                 className="mx_EmojiPicker_item_wrapper"
                 label={emoji.unicode}
+                disabled={this.props.disabled}
             >
                 <div className={`mx_EmojiPicker_item ${isSelected ? 'mx_EmojiPicker_item_selected' : ''}`}>
                     { emoji.unicode }
diff --git a/src/components/views/emojipicker/EmojiPicker.tsx b/src/components/views/emojipicker/EmojiPicker.tsx
index 461ef4f079a..e32f20b78b6 100644
--- a/src/components/views/emojipicker/EmojiPicker.tsx
+++ b/src/components/views/emojipicker/EmojiPicker.tsx
@@ -37,6 +37,7 @@ interface IProps {
     selectedEmojis?: Set<string>;
     showQuickReactions?: boolean;
     onChoose(unicode: string): boolean;
+    isEmojiDisabled?: (unicode: string) => boolean;
 }
 
 interface IState {
@@ -261,6 +262,7 @@ class EmojiPicker extends React.Component<IProps, IState> {
                                 onClick={this.onClickEmoji}
                                 onMouseEnter={this.onHoverEmoji}
                                 onMouseLeave={this.onHoverEmojiEnd}
+                                isEmojiDisabled={this.props.isEmojiDisabled}
                                 selectedEmojis={this.props.selectedEmojis}
                             />
                         );
diff --git a/src/components/views/emojipicker/ReactionPicker.tsx b/src/components/views/emojipicker/ReactionPicker.tsx
index 4a0d15b7292..464480ef5ae 100644
--- a/src/components/views/emojipicker/ReactionPicker.tsx
+++ b/src/components/views/emojipicker/ReactionPicker.tsx
@@ -73,7 +73,7 @@ class ReactionPicker extends React.Component<IProps, IState> {
         }
     }
 
-    private getReactions() {
+    private getReactions(): Record<string, string> {
         if (!this.props.reactions) {
             return {};
         }
@@ -95,6 +95,8 @@ class ReactionPicker extends React.Component<IProps, IState> {
         this.props.onFinished();
         const myReactions = this.getReactions();
         if (myReactions.hasOwnProperty(reaction)) {
+            if (this.props.mxEvent.isRedacted() || !this.context.canSelfRedact) return;
+
             MatrixClientPeg.get().redactEvent(this.props.mxEvent.getRoomId(), myReactions[reaction]);
             dis.dispatch<FocusComposerPayload>({
                 action: Action.FocusAComposer,
@@ -119,9 +121,17 @@ class ReactionPicker extends React.Component<IProps, IState> {
         }
     };
 
+    private isEmojiDisabled = (unicode: string): boolean => {
+        if (!this.getReactions()[unicode]) return false;
+        if (this.context.canSelfRedact) return false;
+
+        return true;
+    };
+
     render() {
         return <EmojiPicker
             onChoose={this.onChoose}
+            isEmojiDisabled={this.isEmojiDisabled}
             selectedEmojis={this.state.selectedEmojis}
             showQuickReactions={true}
             data-testid='mx_ReactionPicker'
diff --git a/src/components/views/messages/ReactionsRow.tsx b/src/components/views/messages/ReactionsRow.tsx
index 2ead0ecbbd5..d0190fd5842 100644
--- a/src/components/views/messages/ReactionsRow.tsx
+++ b/src/components/views/messages/ReactionsRow.tsx
@@ -183,7 +183,10 @@ export default class ReactionsRow extends React.PureComponent<IProps, IState> {
                 mxEvent={mxEvent}
                 reactionEvents={events}
                 myReactionEvent={myReactionEvent}
-                disabled={!this.context.canReact}
+                disabled={
+                    !this.context.canReact ||
+                    (myReactionEvent && !myReactionEvent.isRedacted() && !this.context.canSelfRedact)
+                }
             />;
         }).filter(item => !!item);
 
diff --git a/src/components/views/messages/ReactionsRowButton.tsx b/src/components/views/messages/ReactionsRowButton.tsx
index d3fcb2faa62..9188fd2ff73 100644
--- a/src/components/views/messages/ReactionsRowButton.tsx
+++ b/src/components/views/messages/ReactionsRowButton.tsx
@@ -47,6 +47,7 @@ interface IState {
 
 export default class ReactionsRowButton extends React.PureComponent<IProps, IState> {
     static contextType = MatrixClientContext;
+    public context!: React.ContextType<typeof MatrixClientContext>;
 
     state = {
         tooltipRendered: false,
diff --git a/src/contexts/RoomContext.ts b/src/contexts/RoomContext.ts
index 6dd705870a1..6ca5ed60c22 100644
--- a/src/contexts/RoomContext.ts
+++ b/src/contexts/RoomContext.ts
@@ -43,6 +43,7 @@ const RoomContext = createContext<IRoomState>({
     showTopUnreadMessagesBar: false,
     statusBarVisible: false,
     canReact: false,
+    canSelfRedact: false,
     canSendMessages: false,
     resizing: false,
     layout: Layout.Group,
diff --git a/test/components/views/rooms/MessageComposerButtons-test.tsx b/test/components/views/rooms/MessageComposerButtons-test.tsx
index d9f867b67e4..f0e736c032c 100644
--- a/test/components/views/rooms/MessageComposerButtons-test.tsx
+++ b/test/components/views/rooms/MessageComposerButtons-test.tsx
@@ -209,6 +209,7 @@ function createRoomState(room: Room, narrow: boolean): IRoomState {
         shouldPeek: true,
         membersLoaded: false,
         numUnreadMessages: 0,
+        canSelfRedact: false,
         canPeek: false,
         showApps: false,
         isPeeking: false,
diff --git a/test/components/views/rooms/SendMessageComposer-test.tsx b/test/components/views/rooms/SendMessageComposer-test.tsx
index 5ab7a1705e5..014f5af66ea 100644
--- a/test/components/views/rooms/SendMessageComposer-test.tsx
+++ b/test/components/views/rooms/SendMessageComposer-test.tsx
@@ -48,21 +48,18 @@ const WrapWithProviders: React.FC<{
 </MatrixClientContext.Provider>;
 
 describe('<SendMessageComposer/>', () => {
-    const defaultRoomContext = {
+    const defaultRoomContext: IRoomState = {
         roomLoading: true,
         peekLoading: false,
         shouldPeek: true,
         membersLoaded: false,
         numUnreadMessages: 0,
-        searching: false,
-        guestsCanJoin: false,
         canPeek: false,
         showApps: false,
         isPeeking: false,
         showRightPanel: true,
         joining: false,
         atEndOfLiveTimeline: true,
-        atEndOfLiveTimelineInit: false,
         showTopUnreadMessagesBar: false,
         statusBarVisible: false,
         canReact: false,
@@ -82,6 +79,9 @@ describe('<SendMessageComposer/>', () => {
         matrixClientIsReady: false,
         timelineRenderingType: TimelineRenderingType.Room,
         liveTimeline: undefined,
+        canSelfRedact: false,
+        resizing: false,
+        narrow: false,
     };
     describe("createMessageContent", () => {
         const permalinkCreator = jest.fn() as any;