diff --git a/unittests/windowstests.py b/unittests/windowstests.py
index 37e92996d97a..c201953276cc 100644
--- a/unittests/windowstests.py
+++ b/unittests/windowstests.py
@@ -462,6 +462,9 @@ def test_non_utf8_fails(self):
 
     @unittest.skipIf(is_cygwin(), "Needs visual studio")
     def test_vsenv_option(self):
+        if mesonbuild.environment.detect_msys2_arch():
+            # https://github.com/msys2-contrib/cpython-mingw/issues/141
+            raise SkipTest('mingw python fails with /bin being removed from PATH')
         if self.backend is not Backend.ninja:
             raise SkipTest('Only ninja backend is valid for test')
         env = os.environ.copy()