diff --git a/change/react-native-windows-3adee0f5-93e2-4451-bc8a-967121f90520.json b/change/react-native-windows-3adee0f5-93e2-4451-bc8a-967121f90520.json
new file mode 100644
index 00000000000..caf3f75e930
--- /dev/null
+++ b/change/react-native-windows-3adee0f5-93e2-4451-bc8a-967121f90520.json
@@ -0,0 +1,7 @@
+{
+  "type": "prerelease",
+  "comment": "Fix bug when blur command received on node without XamlRoot",
+  "packageName": "react-native-windows",
+  "email": "erozell@outlook.com",
+  "dependentChangeType": "patch"
+}
diff --git a/vnext/Microsoft.ReactNative/Modules/NativeUIManager.cpp b/vnext/Microsoft.ReactNative/Modules/NativeUIManager.cpp
index 8b911866745..8da4aa1dea5 100644
--- a/vnext/Microsoft.ReactNative/Modules/NativeUIManager.cpp
+++ b/vnext/Microsoft.ReactNative/Modules/NativeUIManager.cpp
@@ -1171,7 +1171,9 @@ void NativeUIManager::blur(int64_t reactTag) {
   if (auto shadowNode = static_cast<ShadowNodeBase *>(m_host->FindShadowNodeForTag(reactTag))) {
     // Only blur if current UI is focused to avoid problem described in PR #2687
     const auto xamlRoot = tryGetXamlRoot(shadowNode->m_rootTag);
-    if (shadowNode->GetView() == xaml::Input::FocusManager::GetFocusedElement(xamlRoot)) {
+    const auto focusedElement = xamlRoot ? xaml::Input::FocusManager::GetFocusedElement(xamlRoot)
+                                         : xaml::Input::FocusManager::GetFocusedElement();
+    if (shadowNode->GetView() == focusedElement) {
       if (auto reactControl = GetParentXamlReactControl(reactTag).get()) {
         reactControl.as<winrt::Microsoft::ReactNative::implementation::ReactRootView>()->blur(shadowNode->GetView());
       } else {