diff --git a/src/client/interpreter/interpreterService.ts b/src/client/interpreter/interpreterService.ts
index 3cfb651977bb..b595fc2365a8 100644
--- a/src/client/interpreter/interpreterService.ts
+++ b/src/client/interpreter/interpreterService.ts
@@ -31,7 +31,7 @@ import {
     PythonEnvironmentsChangedEvent,
 } from './contracts';
 import { traceError, traceLog } from '../logging';
-import { Commands, PYTHON_LANGUAGE } from '../common/constants';
+import { Commands, PVSC_EXTENSION_ID, PYTHON_LANGUAGE } from '../common/constants';
 import { reportActiveInterpreterChanged } from '../environmentApi';
 import { IPythonExecutionFactory } from '../common/process/types';
 import { Interpreters } from '../common/utils/localize';
@@ -138,7 +138,12 @@ export class InterpreterService implements Disposable, IInterpreterService {
                     return false;
                 }
                 const document = this.docManager.activeTextEditor?.document;
-                if (document?.fileName.endsWith('settings.json')) {
+                // Output channel for MS Python related extensions. These contain "ms-python" in their ID.
+                const pythonOutputChannelPattern = PVSC_EXTENSION_ID.split('.')[0];
+                if (
+                    document?.fileName.endsWith('settings.json') ||
+                    document?.fileName.includes(pythonOutputChannelPattern)
+                ) {
                     return false;
                 }
                 return document?.languageId !== PYTHON_LANGUAGE;