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mgpo-base.owl
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mgpo-base.owl
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<?xml version="1.0"?>
<rdf:RDF xmlns="http://purl.obolibrary.org/obo/mgpo/mgpo-base.owl#"
xml:base="http://purl.obolibrary.org/obo/mgpo/mgpo-base.owl"
xmlns:dc="http://purl.org/dc/elements/1.1/"
xmlns:obo="http://purl.obolibrary.org/obo/"
xmlns:owl="http://www.w3.org/2002/07/owl#"
xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
xmlns:xml="http://www.w3.org/XML/1998/namespace"
xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
xmlns:foaf="http://xmlns.com/foaf/0.1/"
xmlns:pato="http://purl.obolibrary.org/obo/pato#"
xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#">
<owl:Ontology rdf:about="http://purl.obolibrary.org/obo/mgpo/mgpo-base.owl">
<owl:versionIRI rdf:resource="http://purl.obolibrary.org/obo/mgpo/releases/2024-04-18/mgpo-base.owl"/>
<dc:type rdf:resource="http://purl.obolibrary.org/obo/IAO_8000001"/>
<rdfs:comment>Testing approach where occupancy and composition and levels phenotypes are all grouped as siblings under a abnormal glycosylation parent. This approach should simplify integration with HPO.
The challenge remains w.r.t. confusion around when to annotate to a level vs a composition phenotype (e.g. abnormal fucosylated glycan levels vs abnormal glycan fucose content), but we can try to clarify the rules here, and see what feedback we get when we test. Also, it may be fine just to say annotate to both if both would apply, and this doesn't really hurt anything.</rdfs:comment>
<owl:versionInfo>2024-04-18</owl:versionInfo>
</owl:Ontology>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Annotation properties
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://purl.obolibrary.org/obo/IAO_0000115 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
<!-- http://purl.obolibrary.org/obo/MGPO_0002032 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/MGPO_0002032">
<rdfs:label xml:lang="en">mgpo_editor_note</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/MGPO_0002037 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/MGPO_0002037">
<rdfs:label xml:lang="en">alternative term</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.obolibrary.org/obo/MGPO_0002098 -->
<owl:AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/MGPO_0002098">
<rdfs:label xml:lang="en">example</rdfs:label>
</owl:AnnotationProperty>
<!-- http://purl.org/dc/elements/1.1/type -->
<owl:AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/type"/>
<!-- http://www.geneontology.org/formats/oboInOwl#hasExactSynonym -->
<owl:AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Object Properties
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://purl.obolibrary.org/obo/BFO_0000050 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000050"/>
<!-- http://purl.obolibrary.org/obo/BFO_0000051 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/BFO_0000051"/>
<!-- http://purl.obolibrary.org/obo/RO_0000052 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000052"/>
<!-- http://purl.obolibrary.org/obo/RO_0002503 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002503"/>
<!-- http://purl.obolibrary.org/obo/RO_0002573 -->
<owl:ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0002573"/>
<!--
///////////////////////////////////////////////////////////////////////////////////////
//
// Classes
//
///////////////////////////////////////////////////////////////////////////////////////
-->
<!-- http://purl.obolibrary.org/obo/CHEBI_17089 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_17089"/>
<!-- http://purl.obolibrary.org/obo/CHEBI_24396 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_24396"/>
<!-- http://purl.obolibrary.org/obo/CHEBI_35258 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35258"/>
<!-- http://purl.obolibrary.org/obo/CHEBI_35381 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35381"/>
<!-- http://purl.obolibrary.org/obo/CHEBI_50699 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_50699"/>
<!-- http://purl.obolibrary.org/obo/CHEBItemp_0002131 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBItemp_0002131"/>
<!-- http://purl.obolibrary.org/obo/CHEBItemp_0002132 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBItemp_0002132"/>
<!-- http://purl.obolibrary.org/obo/CHEBItemp_0002133 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBItemp_0002133"/>
<!-- http://purl.obolibrary.org/obo/CHEBItemp_0002135 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBItemp_0002135"/>
<!-- http://purl.obolibrary.org/obo/CHEBItemp_0002136 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBItemp_0002136"/>
<!-- http://purl.obolibrary.org/obo/CHEBItemp_0002143 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBItemp_0002143"/>
<!-- http://purl.obolibrary.org/obo/CHEBItemp_0002148 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBItemp_0002148"/>
<!-- http://purl.obolibrary.org/obo/CHEBItemp_0002164 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBItemp_0002164"/>
<!-- http://purl.obolibrary.org/obo/CHEBItemp_0002236 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBItemp_0002236"/>
<!-- http://purl.obolibrary.org/obo/CHEBItemp_0002237 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/CHEBItemp_0002237"/>
<!-- http://purl.obolibrary.org/obo/GO_0004576 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0004576"/>
<!-- http://purl.obolibrary.org/obo/GO_0016757 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0016757"/>
<!-- http://purl.obolibrary.org/obo/GO_0016798 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/GO_0016798"/>
<!-- http://purl.obolibrary.org/obo/MGPO_0001001 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0001001">
<rdfs:label xml:lang="en">Phenotype</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002001 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002001">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002028"/>
<obo:IAO_0000115>An abnormality in the process of glycan catabolism or biosynthesis.</obo:IAO_0000115>
<rdfs:label xml:lang="en">abnormal glycan metabolism</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002002 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002002">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0000070"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBItemp_0002131"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002573"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000460"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0001001"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0000070"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBItemp_0002131"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002573"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000460"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000115>An abnormal level of glycan.</obo:IAO_0000115>
<obo:IAO_0000115>An increase or decrease in the amount of a type or specific species of glycan present in the body, cell, or specific compartment therein.</obo:IAO_0000115>
<obo:MGPO_0002032>Here we make distinction between free and conjugated only deeper in the hierarchy - since often we don’t know origin. Often MS-based phenotypes simply refer to altered levels of a class of glycans - and these clearly go here. Other cases are trickier - e.g. elevated levels of mannose rich cores species. Here, if an MS-based phenotype cannot be best characterized with a residue-specific composition class, they should be documented here as a levels phenotype. Challenge is that the curator has to understand the expert interpretation of thee data to make selection here, and these interpretations can be quite nuanced/subjective.</obo:MGPO_0002032>
<rdfs:label>abnormal glycan level</rdfs:label>
<rdfs:label xml:lang="en">abnormal glycan levels</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002003 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002003">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0002083"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBItemp_0002148"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002503"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBItemp_0002164"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002573"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000460"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002009"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0002083"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBItemp_0002148"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002503"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBItemp_0002164"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002573"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000460"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000115>An increase or decrease in the number of glycan chains conjugated to an aglycone target.</obo:IAO_0000115>
<obo:MGPO_0002032>Relevant Classification Axes (in order shown for exemplar classes below):
1 glycosylation/target type (N-linked vs O-linked vs proteoglycan)
1.1 glycosylated residue (e.g. Asn, Ser, Thr)
1.2 specific aglycone target (e.g. transferrin)
1.2.1 anatomical/cellular location (e.g. serum, golgi)
</obo:MGPO_0002032>
<rdfs:comment>"Occupancy" is used here to describe the extent of conjugation of a glycan chain to glycosylation sites on an aglycone target. Abnormal occupancy does not speak to the structure or composition of the glycan chain, just the relative abundance of glycan chains on some protein or lipid target.</rdfs:comment>
<rdfs:label xml:lang="en">abnormal glycan occupancy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002004 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002004">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002028"/>
<rdfs:comment>A change in the molecular structure of a glycan, including altered sugar composition, chain length, linkage or branching patterns, or modifications on a sugar residues</rdfs:comment>
<rdfs:comment>Former logical definition:
'has part' some
(structure
and ('has modifier' some abnormal)
and ('inheres in' some glycan))</rdfs:comment>
<rdfs:comment>The distinction between abnormal glycan levels and abnormal glycan structure/composition is confounded by the fact that specific phenotypes in both categories are typically reported in the literature by describing the amount of a particular type of glycan. For example, "increased sialylated oligosaccharides in the lysosome" is verbatim text reporting a ‘compositional’ defect, and "increased levels of complex N-Glycans in the serum" is verbatim text reporting a ‘level’ defect. The key difference is that the former defect indicates that glycans contain abnormalities in their sialyl content that make them compositionally different that glycan end products normally found in the lysosome. And biologically, this defect likely results from defects in glycosylation, deglycosylation, or isomerase enzymes. By contrast, the latter defect does not reflect a structural/compositional abnormality in the specified glycan, but rather that the level of a certain normal type of glycan end-product is elevated. Compared to a compositional phenotype, this defect likely has a very different biological cause related to abnormal glycan degradation or trafficking.</rdfs:comment>
<rdfs:label xml:lang="en">abnormal glycan structure</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002005 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002005">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002028"/>
<obo:IAO_0000115>Abnormality in a biological process that has a glycan or glycan-containing entity as a product or active participant.</obo:IAO_0000115>
<rdfs:label xml:lang="en">abnormal glycan-related process</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002006 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002006">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002005"/>
<obo:IAO_0000115>An abnormality in the process of a glycan binding to its target.</obo:IAO_0000115>
<rdfs:label xml:lang="en">abnormal glycan binding</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002007 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002007">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002028"/>
<obo:IAO_0000115>An abnormality in the process of glycan deglycosylation.</obo:IAO_0000115>
<rdfs:label xml:lang="en">abnormal deglycosylation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002008 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002008">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002001"/>
<rdfs:label xml:lang="en">abnormal glycan catabolism</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002009 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002009">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0001001"/>
<obo:IAO_0000115>An abnormality in the structure or composition of glycans, or their attachment to aglycone conjugation targets.</obo:IAO_0000115>
<obo:MGPO_0002032>Can we logically define this . . . a ssome abnormal structure that inheres in some molecular entity that has part some gycan? This wont work if we have the abnormal glycosylation activity phenotypes in this hierarchy.</obo:MGPO_0002032>
<obo:MGPO_0002037>abnormal glycan structure</obo:MGPO_0002037>
<obo:MGPO_0002037>abnormal glycosylation structure</obo:MGPO_0002037>
<rdfs:comment>Abnormal glycosylation phenotypes cover altered glycan composition, including altered sugar residue content, chain length, linkage, or branching patterns, as well as altered occupancy, characterized by abnormal degree or pattens or conjugation of glycan chains to aglycone targets.
Abnormal glycosylation phenotypes typically result from defects in the machinery that directly (glycosyltransferase, glycosidase, oligosaccharyltransferase enzymes) or indierctly (isomerasaes, transport proteins, chaperones, glycan residue synthesis/activation pathways, etc.) contribute to the building/remodeling of glycan chains, or their attachement to aglycone targets.</rdfs:comment>
<rdfs:label xml:lang="en">abnormal glycosylation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002010 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002010">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0002009"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBItemp_0002131"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002573"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000460"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002009"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0002009"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBItemp_0002131"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002573"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000460"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000115>A change in the structure of a glycan chain due to altered branching patterns. </obo:IAO_0000115>
<obo:MGPO_0002032>Relevant Classification Axes (in order shown for exemplar classes above):
1 attachment (conjugated vs free glycans)
1.1 aglycone class (e.g. glycoprotein-linked vs glycopeptide-linked)
1.1.1 more specific aglycone class (e.g. N-glycan vs O-glycan for proteins)
</obo:MGPO_0002032>
<rdfs:label xml:lang="en">abnormal glycan branching</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002011 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002011">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0002083"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBItemp_0002131"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002503"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBItemp_0002132"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002573"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000460"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002009"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0002083"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBItemp_0002131"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002503"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBItemp_0002132"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002573"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000460"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000115>A change in the strucutre of a glycan chain due to variations in number and/or type of sugar residue constituents - typically an increased or decreased abundance of a given type of residue, or the substitution of on residue type for another.</obo:IAO_0000115>
<obo:MGPO_0002037>abnormal glycan chain composition</obo:MGPO_0002037>
<rdfs:comment>abnormal glycosylation of glycans</rdfs:comment>
<rdfs:label xml:lang="en">abnormal glycan composition</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002012 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002012">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0002083"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17089"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002503"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBItemp_0002135"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002573"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000460"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002003"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002201"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0002083"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17089"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002503"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBItemp_0002135"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002573"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000460"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000115>An increase or decrease in the number of N-glycan chains conjugated to aglycone targets.</obo:IAO_0000115>
<rdfs:label xml:lang="en">abnormal N-linked glycoprotein occupancy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002013 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002013">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0002083"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17089"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002503"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBItemp_0002136"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002573"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000460"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002003"/>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002202"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0002083"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_17089"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002503"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBItemp_0002136"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002573"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000460"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000115>An increase or decrease in the number of O-glycan chains conjugated to aglycone targets.</obo:IAO_0000115>
<rdfs:label xml:lang="en">abnormal O-linked glycoprotein occupancy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002017 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002017">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002036"/>
<obo:IAO_0000115>Altered IDUA enzymatic activity in an organism, cell, or part thereof.</obo:IAO_0000115>
<rdfs:label xml:lang="en">abnormal IDUA activity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002018 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002018">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002008"/>
<rdfs:label xml:lang="en">abnormal heparan sulfate degradation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002019 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002019">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002006"/>
<rdfs:label xml:lang="en">abnormal R-type lectin binding</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002023 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002023">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002028"/>
<obo:IAO_0000115>An increase or decrease in the number of N-glycan chains conjugated to transferrin protein.</obo:IAO_0000115>
<rdfs:label xml:lang="en">abnormal transferrin N-glycan occupancy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002024 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002024">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002023"/>
<obo:IAO_0000115>An increase or decrease in the number of N-glycan chains conjugated to transferrin protein in blood serum.</obo:IAO_0000115>
<rdfs:label xml:lang="en">abnormal serum transferrin N-glycan occupancy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002027 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002027">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002028"/>
<obo:IAO_0000115>An increase or decrease in the amount or concentration of normal biantennary N-gycan structures present in the golgi complex.</obo:IAO_0000115>
<rdfs:label xml:lang="en">abnormal golgi biantennary N-glycan levels</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002028 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002028">
<rdfs:label xml:lang="en">DeprecatedClass</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002029 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002029">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002028"/>
<obo:IAO_0000115>An alteration in the activity of a molecular entity such as an enzyme or transporter protein that acts on glycans or glycan-containing entities.</obo:IAO_0000115>
<rdfs:label xml:lang="en">abnormal glycan-related activity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002030 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002030">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002001"/>
<rdfs:label xml:lang="en">abnormal glycan biosynthesis</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002031 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002031">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002008"/>
<rdfs:label xml:lang="en">abnormal glycosaminoglycan degradation</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002033 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002033">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002028"/>
<obo:IAO_0000115>A phenotype characterized by abnormality in the levels or structural composition of a glycan.</obo:IAO_0000115>
<rdfs:comment>previous logical def: '
has part' some
(quality
and ('has modifier' some abnormal)
and ('inheres in' some glycan))</rdfs:comment>
<rdfs:label xml:lang="en">abnormal glycan phenotype</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002035 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002035">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002028"/>
<obo:IAO_0000115>Altered glycosyltransferase activity in an organism, cell, or part thereof.</obo:IAO_0000115>
<rdfs:label xml:lang="en">abnormal glycosyltransferase activity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002036 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002036">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002028"/>
<obo:IAO_0000115>Altered glycosidase enzymatic activity in an organism, cell, or part thereof.</obo:IAO_0000115>
<obo:MGPO_0002037 xml:lang="en">abnormal glycosyl-hydrolase activity</obo:MGPO_0002037>
<rdfs:label>abnormal glycosidase activity</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002038 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002038">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002209"/>
<obo:IAO_0000115>An increase or decrease in the extent of number of glycan chains conjugated to proteoglycans.</obo:IAO_0000115>
<rdfs:comment>Former logical def:
'has part' some
('altered number of'
and ('has modifier' some abnormal)
and ('inheres in' some proteoglycan)
and (towards some 'conjugated glycan chain'))</rdfs:comment>
<rdfs:label xml:lang="en">abnormal proteoglycan occupancy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002039 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002039">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002028"/>
<obo:IAO_0000115>An increase or decrease in the number of N-glycan chains conjugated to asparagine residues on aglycone targets.</obo:IAO_0000115>
<rdfs:label xml:lang="en">abnormal N-linked glycoprotein asparagine occupancy</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002041 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002041">
<owl:equivalentClass>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0000122"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBItemp_0002131"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002573"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000460"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</owl:equivalentClass>
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002009"/>
<rdfs:subClassOf>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/BFO_0000051"/>
<owl:someValuesFrom>
<owl:Class>
<owl:intersectionOf rdf:parseType="Collection">
<rdf:Description rdf:about="http://purl.obolibrary.org/obo/PATO_0000122"/>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000052"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBItemp_0002131"/>
</owl:Restriction>
<owl:Restriction>
<owl:onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0002573"/>
<owl:someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/PATO_0000460"/>
</owl:Restriction>
</owl:intersectionOf>
</owl:Class>
</owl:someValuesFrom>
</owl:Restriction>
</rdfs:subClassOf>
<obo:IAO_0000115>A change in the strucutre of a glycan chain due to variations in the number of sugar residue constituents.</obo:IAO_0000115>
<obo:MGPO_0002032>Relevant Classification Axes (in order shown for exemplar classes above):
1 attachment (conjugated vs free glycans)
1.1 aglycone class (e.g. glycoprotein-linked vs glycolipid-linked)
1.1.1 more specific aglycone class (e.g. N-glycan vs O-glycan for proteins)</obo:MGPO_0002032>
<obo:MGPO_0002037>abnormal length of glycan species</obo:MGPO_0002037>
<rdfs:label xml:lang="en">abnormal glycan length</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002042 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002042">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002028"/>
<obo:IAO_0000115>A change in the strucutre of a glycan chain due to altered types of linkages between sugar residues. </obo:IAO_0000115>
<obo:MGPO_0002032>Relevant Classification Axes (in order shown for exemplar classes above):
1 attachment (conjugated vs free glycans)
1.1 aglycone class (e.g. glycoprotein-linked vs glycopeptide-linked)
1.1.1 more specific aglycone class (e.g. N-glycan vs O-glycan for proteins)</obo:MGPO_0002032>
<rdfs:label xml:lang="en">abnormal glycan linkage</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002048 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002048">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002028"/>
<obo:IAO_0000115>A change in the strucutre of a serum-localized N-glycan chain due to variations in number and/or location of sialyl residues - typically an increased or decreased abundance of sialyl residues, or the substitution of sialyl residues for another residue type.</obo:IAO_0000115>
<rdfs:label xml:lang="en">abnormal sialyl content in serum N-glycans</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002050 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002050">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002028"/>
<obo:IAO_0000115>A change in the strucutre of a glycolipid glycan chain due to variations in number and/or type of sugar residue constituents - typically an increased or decreased abundance of a given type of residue, or the substitution of on residue type for another.</obo:IAO_0000115>
<rdfs:label xml:lang="en">abnormal glycolipid glycan composition</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002051 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002051">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002050"/>
<rdfs:label xml:lang="en">abnormal glycosphingolipid glycan composition</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002052 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002052">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002050"/>
<rdfs:label xml:lang="en">abnormal glycoglycerolipid glycan composition</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002053 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002053">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002028"/>
<obo:IAO_0000115>A change in the strucutre of a lipopolysaccharide glycan chain due to variations in number and/or type of sugar residue constituents - typically an increased or decreased abundance of a given type of residue, or the substitution of on residue type for another.</obo:IAO_0000115>
<rdfs:label xml:lang="en">abnormal lipopolysaccharide glycan composition</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002054 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002054">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002028"/>
<rdfs:label xml:lang="en">abnormal conjugated glycan length</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002055 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002055">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002028"/>
<rdfs:label xml:lang="en">abnormal free glycan length</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002056 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002056">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002028"/>
<rdfs:label xml:lang="en">abnormal glycoprotein glycan length</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002057 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002057">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002028"/>
<rdfs:label xml:lang="en">abnormal glycolipid glycan length</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002058 -->
<owl:Class rdf:about="http://purl.obolibrary.org/obo/MGPO_0002058">
<rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MGPO_0002028"/>
<rdfs:label xml:lang="en">abnormal lipopolysaccharide glycan length</rdfs:label>
</owl:Class>
<!-- http://purl.obolibrary.org/obo/MGPO_0002059 -->