diff --git a/packages/material-ui-lab/src/useAutocomplete/useAutocomplete.js b/packages/material-ui-lab/src/useAutocomplete/useAutocomplete.js
index f3ba2747b2a7db..378b30e56a98a7 100644
--- a/packages/material-ui-lab/src/useAutocomplete/useAutocomplete.js
+++ b/packages/material-ui-lab/src/useAutocomplete/useAutocomplete.js
@@ -734,7 +734,7 @@ export default function useAutocomplete(props) {
 
   // Prevent input blur when interacting with the combobox
   const handleMouseDown = event => {
-    if (event.target.nodeName !== 'INPUT') {
+    if (event.target.getAttribute('id') !== id) {
       event.preventDefault();
     }
   };