diff --git a/.github/workflows/tests.yml b/.github/workflows/tests.yml
index e4be56bd..1fadbd91 100644
--- a/.github/workflows/tests.yml
+++ b/.github/workflows/tests.yml
@@ -8,7 +8,7 @@ jobs:
 
         strategy:
             matrix:
-                python-version: ["2.7", "3.5", "3.6", "3.7", "3.8", "3.9", "3.10", "3.11", "pypy2.7", "pypy3.9"]
+                python-version: ["3.7", "3.8", "3.9", "3.10", "3.11", "3.12", "pypy3.9"]
 
         steps:
 
diff --git a/NEWS b/NEWS
index b3ac0537..84d8902e 100644
--- a/NEWS
+++ b/NEWS
@@ -2,6 +2,8 @@
 
 * Support attributes in HTML paths in style mappings.
 
+* Drop support for Python 2.7, Python 3.5 and Python 3.6.
+
 # 1.6.0
 
 * Support merged paragraphs when revisions are tracked.
diff --git a/setup.py b/setup.py
index 55e66449..8931a4a2 100644
--- a/setup.py
+++ b/setup.py
@@ -25,23 +25,20 @@ def read(fname):
     install_requires=[
         "cobble>=0.1.3,<0.2",
     ],
-    python_requires='>=2.7, !=3.0.*, !=3.1.*, !=3.2.*, !=3.3.*, !=3.4.*',
+    python_requires='>=3.7',
     license="BSD-2-Clause",
     classifiers=[
         'Development Status :: 5 - Production/Stable',
         'Intended Audience :: Developers',
         'License :: OSI Approved :: BSD License',
         'Programming Language :: Python',
-        'Programming Language :: Python :: 2',
-        'Programming Language :: Python :: 2.7',
         'Programming Language :: Python :: 3',
-        'Programming Language :: Python :: 3.5',
-        'Programming Language :: Python :: 3.6',
         'Programming Language :: Python :: 3.7',
         'Programming Language :: Python :: 3.8',
         'Programming Language :: Python :: 3.9',
         'Programming Language :: Python :: 3.10',
         'Programming Language :: Python :: 3.11',
+        'Programming Language :: Python :: 3.12',
     ],
 )
 
diff --git a/tox.ini b/tox.ini
index 00174d33..b32b32bb 100644
--- a/tox.ini
+++ b/tox.ini
@@ -1,5 +1,5 @@
 [tox]
-envlist = py27,py35,py36,py37,py38,py39,py310,py311,pypy,pypy3
+envlist = py37,py38,py39,py310,py311,py312,pypy3
 [testenv]
 changedir = {envtmpdir}
 deps=-r{toxinidir}/test-requirements.txt