diff --git a/README.md b/README.md
index 1e944316d..83cbbd27d 100644
--- a/README.md
+++ b/README.md
@@ -20,7 +20,7 @@ When using or transitioning to Go modules support:
 ```bash
 # Go client latest or explicit version
 go get github.com/nats-io/nats.go/@latest
-go get github.com/nats-io/nats.go/@v1.9.0
+go get github.com/nats-io/nats.go/@v1.9.1
 
 # For latest NATS Server, add /v2 at the end
 go get github.com/nats-io/nats-server/v2
diff --git a/nats.go b/nats.go
index 756baa7cb..911df590e 100644
--- a/nats.go
+++ b/nats.go
@@ -45,7 +45,7 @@ import (
 
 // Default Constants
 const (
-	Version                 = "1.9.0"
+	Version                 = "1.9.1"
 	DefaultURL              = "nats://127.0.0.1:4222"
 	DefaultPort             = 4222
 	DefaultMaxReconnect     = 60
@@ -2656,14 +2656,18 @@ func (nc *Conn) respHandler(m *Msg) {
 		return
 	}
 
+	var mch chan *Msg
+
 	// Grab mch
 	rt := nc.respToken(m.Subject)
-	mch := nc.respMap[rt]
-	// Delete the key regardless, one response only.
-	delete(nc.respMap, rt)
-	// If something went wrong and we only have one entry, use that.
-	// This can happen if the system rewrites the subject, e.g. js.
-	if mch == nil && len(nc.respMap) == 1 {
+	if rt != _EMPTY_ {
+		mch = nc.respMap[rt]
+		// Delete the key regardless, one response only.
+		delete(nc.respMap, rt)
+	} else if len(nc.respMap) == 1 {
+		// If the server has rewritten the subject, the response token (rt)
+		// will not match (could be the case with JetStream). If that is the
+		// case and there is a single entry, use that.
 		for k, v := range nc.respMap {
 			mch = v
 			delete(nc.respMap, k)
diff --git a/nats_test.go b/nats_test.go
index f5edec8a1..f8ba7a0ff 100644
--- a/nats_test.go
+++ b/nats_test.go
@@ -2264,3 +2264,47 @@ func TestRequestLeaksMapEntries(t *testing.T) {
 		t.Fatalf("Expected 0 entries in response map, got %d", num)
 	}
 }
+
+func TestRequestMultipleReplies(t *testing.T) {
+	o := natsserver.DefaultTestOptions
+	o.Port = -1
+	s := RunServerWithOptions(&o)
+	defer s.Shutdown()
+
+	nc, err := Connect(fmt.Sprintf("nats://%s:%d", o.Host, o.Port))
+	if err != nil {
+		t.Fatalf("Error on connect: %v", err)
+	}
+	defer nc.Close()
+
+	response := []byte("I will help you")
+	nc.Subscribe("foo", func(m *Msg) {
+		m.Respond(response)
+		m.Respond(response)
+	})
+	nc.Flush()
+
+	nc2, err := Connect(fmt.Sprintf("nats://%s:%d", o.Host, o.Port))
+	if err != nil {
+		t.Fatalf("Error on connect: %v", err)
+	}
+	defer nc2.Close()
+
+	errCh := make(chan error, 1)
+	// Send a request on bar and expect nothing
+	go func() {
+		if m, err := nc2.Request("bar", nil, 500*time.Millisecond); m != nil || err == nil {
+			errCh <- fmt.Errorf("Expected no reply, got m=%+v err=%v", m, err)
+			return
+		}
+		errCh <- nil
+	}()
+
+	// Send a request on foo, we use only one of the 2 replies
+	if _, err := nc2.Request("foo", nil, time.Second); err != nil {
+		t.Fatalf("Received an error on Request test: %s", err)
+	}
+	if e := <-errCh; e != nil {
+		t.Fatal(e.Error())
+	}
+}