diff --git a/CHANGELOG.md b/CHANGELOG.md
index 9a071696..c9dcad59 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -18,6 +18,7 @@ and this project adheres to [Semantic Versioning](https://semver.org/spec/v2.0.0
 - No more checks for existence of samplesheet, which made building references fail (building references uses a fake sample sheet if none is provided) [#420](https://github.com/nf-core/rnafusion/pull/420)
 - `--extreme_sensitivity` used for fusioninspector to minimize fusioninspector filtering [#424](https://github.com/nf-core/rnafusion/pull/424)
 - `--extreme_sensitivity` removed in favor of `--max_sensitivity --max_mate_dist 10000000 --annotate --examine_coding_effect` to collect more data from fusioninspector [#426](https://github.com/nf-core/rnafusion/pull/426)
+- `Arriba` updated to 2.4.0 [#429](https://github.com/nf-core/rnafusion/pull/429)
 
 ### Fixed
 
diff --git a/modules/local/arriba/download/main.nf b/modules/local/arriba/download/main.nf
index 166ed69f..860439ad 100644
--- a/modules/local/arriba/download/main.nf
+++ b/modules/local/arriba/download/main.nf
@@ -13,11 +13,11 @@ process ARRIBA_DOWNLOAD {
 
     script:
     """
-    wget https://github.com/suhrig/arriba/releases/download/v2.3.0/arriba_v2.3.0.tar.gz -O arriba_v2.3.0.tar.gz
-    tar -xzvf arriba_v2.3.0.tar.gz
-    rm arriba_v2.3.0.tar.gz
-    mv arriba_v2.3.0/database/* .
-    rm -r arriba_v2.3.0
+    wget https://github.com/suhrig/arriba/releases/download/v2.4.0/arriba_v2.4.0.tar.gz -O arriba_v2.4.0.tar.gz
+    tar -xzvf arriba_v2.4.0.tar.gz
+    rm arriba_v2.4.0.tar.gz
+    mv arriba_v2.4.0/database/* .
+    rm -r arriba_v2.4.0
 
     cat <<-END_VERSIONS > versions.yml
     "${task.process}":
@@ -27,11 +27,11 @@ process ARRIBA_DOWNLOAD {
 
     stub:
     """
-    touch blacklist_hg38_GRCh38_v2.3.0.tsv.gz
-    touch protein_domains_hg38_GRCh38_v2.3.0.gff3
-    touch cytobands_hg38_GRCh38_v2.3.0.tsv
-    touch known_fusions_hg38_GRCh38_v2.3.0.tsv.gz
-    touch protein_domains_hg38_GRCh38_v2.3.0.gff3
+    touch blacklist_hg38_GRCh38_v2.4.0.tsv.gz
+    touch protein_domains_hg38_GRCh38_v2.4.0.gff3
+    touch cytobands_hg38_GRCh38_v2.4.0.tsv
+    touch known_fusions_hg38_GRCh38_v2.4.0.tsv.gz
+    touch protein_domains_hg38_GRCh38_v2.4.0.gff3
 
     cat <<-END_VERSIONS > versions.yml
     "${task.process}":
diff --git a/modules/local/arriba/visualisation/main.nf b/modules/local/arriba/visualisation/main.nf
index 5805a904..cc120119 100644
--- a/modules/local/arriba/visualisation/main.nf
+++ b/modules/local/arriba/visualisation/main.nf
@@ -2,10 +2,10 @@ process ARRIBA_VISUALISATION {
     tag "$meta.id"
     label 'process_medium'
 
-    conda "bioconda::arriba=2.3.0"
+    conda "bioconda::arriba=2.4.0"
     container "${ workflow.containerEngine == 'singularity' && !task.ext.singularity_pull_docker_container ?
-        'https://depot.galaxyproject.org/singularity/arriba:2.3.0--haa8aa89_0' :
-        'quay.io/biocontainers/arriba:2.3.0--haa8aa89_0' }"
+        'https://depot.galaxyproject.org/singularity/arriba:2.4.0--h0033a41_2' :
+        'biocontainers/arriba:2.4.0--h0033a41_2' }"
 
     input:
     tuple val(meta), path(bam), path(bai), path(fusions)
diff --git a/nextflow.config b/nextflow.config
index 925d7a36..5f1e3c2c 100644
--- a/nextflow.config
+++ b/nextflow.config
@@ -66,10 +66,10 @@ params {
     // Path to references
     ensembl_ref                   = "${params.genomes_base}/ensembl"
     arriba_ref                    = "${params.genomes_base}/arriba"
-    arriba_ref_blacklist          = "${params.genomes_base}/arriba/blacklist_hg38_GRCh38_v2.3.0.tsv.gz"
-    arriba_ref_cytobands          = "${params.genomes_base}/arriba/cytobands_hg38_GRCh38_v2.3.0.tsv"
-    arriba_ref_known_fusions      = "${params.genomes_base}/arriba/known_fusions_hg38_GRCh38_v2.3.0.tsv.gz"
-    arriba_ref_protein_domains    = "${params.genomes_base}/arriba/protein_domains_hg38_GRCh38_v2.3.0.gff3"
+    arriba_ref_blacklist          = "${params.genomes_base}/arriba/blacklist_hg38_GRCh38_v2.4.0.tsv.gz"
+    arriba_ref_cytobands          = "${params.genomes_base}/arriba/cytobands_hg38_GRCh38_v2.4.0.tsv"
+    arriba_ref_known_fusions      = "${params.genomes_base}/arriba/known_fusions_hg38_GRCh38_v2.4.0.tsv.gz"
+    arriba_ref_protein_domains    = "${params.genomes_base}/arriba/protein_domains_hg38_GRCh38_v2.4.0.gff3"
     fusioncatcher_ref             = "${params.genomes_base}/fusioncatcher/human_v102"
     starfusion_ref                = "${params.genomes_base}/starfusion/ctat_genome_lib_build_dir"
     starindex_ref                 = "${params.genomes_base}/star"