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This idea would require susceptibility distortion correction, otherwise the references are likely to have different realizations of distortion and the fused reference will be smoother than the individual cases.
What did you mean by affine unbiased coregistration?
Resulting reference files then merged with StructuralReference, and (EPI -> mean EPI) transform saved
Mean EPI aligned to T1w image
This will involve a fairly major refactor from the current, isolated processing of each BOLD series. One problem with this approach is that you can get different results based on whether your analyze all tasks or just a subset in the same process.
However, if we took an EPInorm approach, then there's a common space to which all EPIs are registered that doesn't depend on which subset of tasks have been specified.
Such template would:
How to create it:
Affine unbiased coregistration seems a good method for creating such template.
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