diff --git a/.github/label-pr-config.yml b/.github/label-pr-config.yml
index 463e0c5b9f7837f..f17264e1dc4e203 100644
--- a/.github/label-pr-config.yml
+++ b/.github/label-pr-config.yml
@@ -31,8 +31,8 @@ subSystemLabels:
   /^src\/node_report/: c++, report
   /^src\/node_wasi/: c++, wasi
   /^src\/node_worker/: c++, worker
-  /^src\/quic\/*/: c++, quic, dont-land-on-v14.x, dont-land-on-v12.x
-  /^src\/node_bob*/: c++, quic, dont-land-on-v14.x, dont-land-on-v12.x
+  /^src\/quic\/*/: c++, quic
+  /^src\/node_bob*/: c++, quic
 
   # don't label python files as c++
   /^src\/.+\.py$/: python, needs-ci
@@ -54,7 +54,7 @@ subSystemLabels:
   /^vcbuild\.bat$/: build, windows, needs-ci
   /^(android-)?configure|node\.gyp|common\.gypi$/: build, needs-ci
   # more specific tools
-  /^tools\/gyp/: tools, build, gyp, needs-ci, dont-land-on-v14.x, dont-land-on-v12.x
+  /^tools\/gyp/: tools, build, gyp, needs-ci
   /^tools\/doc\//: tools, doc
   /^tools\/icu\//: tools, i18n-api, icu, needs-ci
   /^tools\/(?:osx-pkg\.pmdoc|pkgsrc)\//: tools, macos, install
@@ -80,11 +80,11 @@ subSystemLabels:
   /^deps\/v8\/tools\/gen-postmortem-metadata\.py/: v8 engine, python, post-mortem
   /^deps\/v8\//: v8 engine
   /^deps\/uvwasi\//: wasi
-  /^deps\/npm\//: npm, fast-track, dont-land-on-v14.x, dont-land-on-v12.x
+  /^deps\/npm\//: npm, fast-track
   /^deps\/nghttp2\/nghttp2\.gyp/: build, http2
   /^deps\/nghttp2\//: http2
-  /^deps\/ngtcp2\//: quic, dont-land-on-v14.x, dont-land-on-v12.x
-  /^deps\/nghttp3\//: quic, dont-land-on-v14.x, dont-land-on-v12.x
+  /^deps\/ngtcp2\//: quic
+  /^deps\/nghttp3\//: quic
   /^deps\/([^/]+)/: dependencies, $1
 
   ## JS subsystems
@@ -99,11 +99,11 @@ subSystemLabels:
   /^lib\/\w+\/streams$/: stream
   /^lib\/.*http2/: http2
   /^lib\/worker_threads.js$/: worker
-  /^lib\/test.js$/: test_runner, dont-land-on-v14.x
+  /^lib\/test.js$/: test_runner
   /^lib\/internal\/url\.js$/: whatwg-url
   /^lib\/internal\/modules\/esm/: esm
   /^lib\/internal\/webstreams/: web streams
-  /^lib\/internal\/test_runner/: test_runner, dont-land-on-v14.x
+  /^lib\/internal\/test_runner/: test_runner
 
   # All other lib/ files map directly
   /^lib\/_(\w+)_\w+\.js?$/: $1  # e.g. _(stream)_wrap
@@ -138,11 +138,11 @@ exlusiveLabels:
   # considered a subsystem of sorts
   /^doc\/api\/n-api.md$/: doc, node-api
   # quic
-  /^doc\/api\/quic.md$/: doc, quic, dont-land-on-v14.x, dont-land-on-v12.x
+  /^doc\/api\/quic.md$/: doc, quic
   # Add worker label to PRs that affect doc/api/worker_threads.md
   /^doc\/api\/worker_threads.md$/: doc, worker
   # test runner documentation
-  /^doc\/api\/test.md$/: doc, test_runner, dont-land-on-v14.x
+  /^doc\/api\/test.md$/: doc, test_runner
   # Automatically tag JS subsystem-specific API doc changes
   /^doc\/api\/(\w+)\.md$/: doc, $1
   # Add deprecations label to PRs that affect doc/api/deprecations.md