diff --git a/test/parallel/test-assert.js b/test/parallel/test-assert.js
index dba40c0a0e3c42..59e67810c2c41f 100644
--- a/test/parallel/test-assert.js
+++ b/test/parallel/test-assert.js
@@ -34,6 +34,12 @@ const { writeFileSync, unlinkSync } = require('fs');
 const { inspect } = require('util');
 const a = assert;
 
+// Disable colored output to prevent color codes from breaking assertion
+// message comparisons. This should only be an issue when process.stdout
+// is a TTY.
+if (process.stdout.isTTY)
+  process.env.NODE_DISABLE_COLORS = '1';
+
 const start = 'Input A expected to strictly deep-equal input B:';
 const actExp = '+ expected - actual';