diff --git a/CMakeLists.txt b/CMakeLists.txt
index a0710834bf..ec46f759b9 100644
--- a/CMakeLists.txt
+++ b/CMakeLists.txt
@@ -60,6 +60,13 @@ else()
     elseif(CMAKE_SIZEOF_VOID_P EQUAL 4)
       set(ARCH x86)
     endif()
+  elseif(CMAKE_SYSTEM_PROCESSOR MATCHES "powerpc")
+    # AIX will report the processor as 'powerpc' even if building in 64-bit mode
+    if(CMAKE_SIZEOF_VOID_P EQUAL 8)
+      set(ARCH ppc64)
+    else()
+      set(ARCH ppc32)
+    endif()
   elseif(CMAKE_SYSTEM_PROCESSOR MATCHES
          "^(aarch64.*|AARCH64.*|arm64.*|ARM64.*)")
     set(ARCH arm64)
diff --git a/cmake/opentelemetry-proto.cmake b/cmake/opentelemetry-proto.cmake
index fa6e185c13..30da0aee16 100644
--- a/cmake/opentelemetry-proto.cmake
+++ b/cmake/opentelemetry-proto.cmake
@@ -348,7 +348,8 @@ if(WITH_OTLP_GRPC)
   target_link_libraries(opentelemetry_proto_grpc PUBLIC opentelemetry_proto)
 
   get_target_property(grpc_lib_type gRPC::grpc++ TYPE)
-  if(grpc_lib_type STREQUAL "SHARED_LIBRARY")
+  get_target_property(opentelemetry_proto_grpc_lib_type opentelemetry_proto_grpc TYPE)
+  if ((grpc_lib_type STREQUAL "SHARED_LIBRARY") OR (opentelemetry_proto_grpc_lib_type STREQUAL "SHARED_LIBRARY"))
     target_link_libraries(opentelemetry_proto_grpc PUBLIC gRPC::grpc++)
   endif()
   set_target_properties(opentelemetry_proto_grpc PROPERTIES EXPORT_NAME
diff --git a/cmake/tools.cmake b/cmake/tools.cmake
index 43c1a7b43f..d01257d386 100644
--- a/cmake/tools.cmake
+++ b/cmake/tools.cmake
@@ -160,6 +160,10 @@ function(project_build_tools_patch_default_imported_config)
       if(IS_ALIAS_TARGET)
         continue()
       endif()
+      get_target_property(IS_ALIASED_TARGET ${TARGET_NAME} ALIASED_TARGET)
+      if (IS_ALIASED_TARGET)
+        continue()
+      endif()
 
       if(CMAKE_VERSION VERSION_LESS "3.19.0")
         get_target_property(TARGET_TYPE_NAME ${TARGET_NAME} TYPE)
diff --git a/sdk/include/opentelemetry/sdk/resource/semantic_conventions.h b/sdk/include/opentelemetry/sdk/resource/semantic_conventions.h
index 9ff985be4d..fd67abc560 100644
--- a/sdk/include/opentelemetry/sdk/resource/semantic_conventions.h
+++ b/sdk/include/opentelemetry/sdk/resource/semantic_conventions.h
@@ -13,6 +13,19 @@
 #include "opentelemetry/common/macros.h"
 #include "opentelemetry/version.h"
 
+/*
+ * Special considerations for HostArchValues
+ *
+ * The sys/systemcfg.h header on AIX is known to define an IA64 macro,
+ * which collides with HostArchValues::IA64.
+ */
+#ifdef _AIX
+#  ifdef IA64
+#    pragma message "Removing define on IA64"
+#    undef IA64
+#  endif
+#endif
+
 OPENTELEMETRY_BEGIN_NAMESPACE
 namespace sdk
 {