diff --git a/cmake/opentelemetry-proto.cmake b/cmake/opentelemetry-proto.cmake
index d6e9e1831c..07863b8f9b 100644
--- a/cmake/opentelemetry-proto.cmake
+++ b/cmake/opentelemetry-proto.cmake
@@ -232,6 +232,10 @@ include_directories("${GENERATED_PROTOBUF_PATH}")
 unset(OTELCPP_PROTO_TARGET_OPTIONS)
 if(CMAKE_SYSTEM_NAME MATCHES "Windows|MinGW|WindowsStore")
   list(APPEND OTELCPP_PROTO_TARGET_OPTIONS STATIC)
+elseif(NOT DEFINED BUILD_SHARED_LIBS OR BUILD_SHARED_LIBS)
+  list(APPEND OTELCPP_PROTO_TARGET_OPTIONS SHARED)
+else()
+  list(APPEND OTELCPP_PROTO_TARGET_OPTIONS STATIC)
 endif()
 
 list(
@@ -288,7 +292,10 @@ if(WITH_OTLP_GRPC)
       target_link_libraries(opentelemetry_proto INTERFACE absl::synchronization)
     endif()
   endif()
-  target_link_libraries(opentelemetry_proto PUBLIC gRPC::grpc++)
+
+  # gRPC can not be linked into more than one dynamic or executable targets. So
+  # we need to link it privately.
+  target_link_libraries(opentelemetry_proto PRIVATE gRPC::grpc++)
 endif()
 
 if(BUILD_SHARED_LIBS)
diff --git a/exporters/otlp/CMakeLists.txt b/exporters/otlp/CMakeLists.txt
index eed80783ac..b85b2532e9 100644
--- a/exporters/otlp/CMakeLists.txt
+++ b/exporters/otlp/CMakeLists.txt
@@ -35,8 +35,9 @@ if(WITH_OTLP_GRPC)
     opentelemetry_exporter_otlp_grpc_client
     PUBLIC opentelemetry_sdk opentelemetry_ext opentelemetry_proto)
 
-  target_link_libraries(opentelemetry_exporter_otlp_grpc_client
-                        PRIVATE gRPC::grpc++)
+  # We have linked gRPC::grpc++ into opentelemetry_proto, so we must not link it
+  # again here.Otherwise the symbols of global variables in some version of gRPC
+  # will conflict on ELF ABI.
   get_target_property(GRPC_INCLUDE_DIRECTORY gRPC::grpc++
                       INTERFACE_INCLUDE_DIRECTORIES)
   if(GRPC_INCLUDE_DIRECTORY)