diff --git a/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/CHANGELOG.md b/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/CHANGELOG.md
index 5fb2f25602d..78fcdd6b874 100644
--- a/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/CHANGELOG.md
+++ b/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/CHANGELOG.md
@@ -13,6 +13,10 @@
   Fixes issues building on Apple Silicon (M1).
   ([#2963](https://github.com/open-telemetry/opentelemetry-dotnet/pull/2963))
 
+* Fixed issue where the configuration of an OTLP exporter could be changed
+  after instantiation by altering the original `OtlpExporterOptions` provided.
+  ([#3066](https://github.com/open-telemetry/opentelemetry-dotnet/pull/3066))
+
 ## 1.2.0-rc3
 
 Released 2022-Mar-04
diff --git a/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/Implementation/ExportClient/BaseOtlpGrpcExportClient.cs b/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/Implementation/ExportClient/BaseOtlpGrpcExportClient.cs
index 12af999d820..49b60c1a97e 100644
--- a/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/Implementation/ExportClient/BaseOtlpGrpcExportClient.cs
+++ b/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/Implementation/ExportClient/BaseOtlpGrpcExportClient.cs
@@ -14,6 +14,7 @@
 // limitations under the License.
 // </copyright>
 
+using System;
 using System.Threading;
 using System.Threading.Tasks;
 using Grpc.Core;
@@ -35,20 +36,23 @@ protected BaseOtlpGrpcExportClient(OtlpExporterOptions options)
 
             ExporterClientValidation.EnsureUnencryptedSupportIsEnabled(options);
 
-            this.Options = options;
+            this.Endpoint = new UriBuilder(options.Endpoint).Uri;
             this.Headers = options.GetMetadataFromHeaders();
+            this.TimeoutMilliseconds = options.TimeoutMilliseconds;
         }
 
-        internal OtlpExporterOptions Options { get; }
-
 #if NETSTANDARD2_1 || NET5_0_OR_GREATER
         internal GrpcChannel Channel { get; set; }
 #else
         internal Channel Channel { get; set; }
 #endif
 
+        internal Uri Endpoint { get; }
+
         internal Metadata Headers { get; }
 
+        internal int TimeoutMilliseconds { get; }
+
         /// <inheritdoc/>
         public abstract bool SendExportRequest(TRequest request, CancellationToken cancellationToken = default);
 
diff --git a/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/Implementation/ExportClient/BaseOtlpHttpExportClient.cs b/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/Implementation/ExportClient/BaseOtlpHttpExportClient.cs
index 46f8dd5c748..5906b7f7798 100644
--- a/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/Implementation/ExportClient/BaseOtlpHttpExportClient.cs
+++ b/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/Implementation/ExportClient/BaseOtlpHttpExportClient.cs
@@ -14,6 +14,7 @@
 // limitations under the License.
 // </copyright>
 
+using System;
 using System.Collections.Generic;
 using System.Net.Http;
 using System.Threading;
@@ -31,15 +32,15 @@ protected BaseOtlpHttpExportClient(OtlpExporterOptions options, HttpClient httpC
             Guard.ThrowIfNull(httpClient);
             Guard.ThrowIfInvalidTimeout(options.TimeoutMilliseconds);
 
-            this.Options = options;
+            this.Endpoint = new UriBuilder(options.Endpoint).Uri;
             this.Headers = options.GetHeaders<Dictionary<string, string>>((d, k, v) => d.Add(k, v));
             this.HttpClient = httpClient;
         }
 
-        internal OtlpExporterOptions Options { get; }
-
         internal HttpClient HttpClient { get; }
 
+        internal Uri Endpoint { get; set; }
+
         internal IReadOnlyDictionary<string, string> Headers { get; }
 
         /// <inheritdoc/>
@@ -55,7 +56,7 @@ public bool SendExportRequest(TRequest request, CancellationToken cancellationTo
             }
             catch (HttpRequestException ex)
             {
-                OpenTelemetryProtocolExporterEventSource.Log.FailedToReachCollector(this.Options.Endpoint, ex);
+                OpenTelemetryProtocolExporterEventSource.Log.FailedToReachCollector(this.Endpoint, ex);
 
                 return false;
             }
diff --git a/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/Implementation/ExportClient/OtlpGrpcLogExportClient.cs b/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/Implementation/ExportClient/OtlpGrpcLogExportClient.cs
index aad3a2146fc..469ae690cb6 100644
--- a/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/Implementation/ExportClient/OtlpGrpcLogExportClient.cs
+++ b/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/Implementation/ExportClient/OtlpGrpcLogExportClient.cs
@@ -43,7 +43,7 @@ public OtlpGrpcLogExportClient(OtlpExporterOptions options, OtlpCollector.LogsSe
         /// <inheritdoc/>
         public override bool SendExportRequest(OtlpCollector.ExportLogsServiceRequest request, CancellationToken cancellationToken = default)
         {
-            var deadline = DateTime.UtcNow.AddMilliseconds(this.Options.TimeoutMilliseconds);
+            var deadline = DateTime.UtcNow.AddMilliseconds(this.TimeoutMilliseconds);
 
             try
             {
@@ -51,7 +51,7 @@ public override bool SendExportRequest(OtlpCollector.ExportLogsServiceRequest re
             }
             catch (RpcException ex)
             {
-                OpenTelemetryProtocolExporterEventSource.Log.FailedToReachCollector(this.Options.Endpoint, ex);
+                OpenTelemetryProtocolExporterEventSource.Log.FailedToReachCollector(this.Endpoint, ex);
 
                 return false;
             }
diff --git a/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/Implementation/ExportClient/OtlpGrpcMetricsExportClient.cs b/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/Implementation/ExportClient/OtlpGrpcMetricsExportClient.cs
index 45553cf7f84..a4980147742 100644
--- a/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/Implementation/ExportClient/OtlpGrpcMetricsExportClient.cs
+++ b/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/Implementation/ExportClient/OtlpGrpcMetricsExportClient.cs
@@ -43,7 +43,7 @@ public OtlpGrpcMetricsExportClient(OtlpExporterOptions options, OtlpCollector.Me
         /// <inheritdoc/>
         public override bool SendExportRequest(OtlpCollector.ExportMetricsServiceRequest request, CancellationToken cancellationToken = default)
         {
-            var deadline = DateTime.UtcNow.AddMilliseconds(this.Options.TimeoutMilliseconds);
+            var deadline = DateTime.UtcNow.AddMilliseconds(this.TimeoutMilliseconds);
 
             try
             {
@@ -51,7 +51,7 @@ public override bool SendExportRequest(OtlpCollector.ExportMetricsServiceRequest
             }
             catch (RpcException ex)
             {
-                OpenTelemetryProtocolExporterEventSource.Log.FailedToReachCollector(this.Options.Endpoint, ex);
+                OpenTelemetryProtocolExporterEventSource.Log.FailedToReachCollector(this.Endpoint, ex);
 
                 return false;
             }
diff --git a/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/Implementation/ExportClient/OtlpGrpcTraceExportClient.cs b/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/Implementation/ExportClient/OtlpGrpcTraceExportClient.cs
index c17f49c4fca..9846d0e1524 100644
--- a/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/Implementation/ExportClient/OtlpGrpcTraceExportClient.cs
+++ b/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/Implementation/ExportClient/OtlpGrpcTraceExportClient.cs
@@ -43,7 +43,7 @@ public OtlpGrpcTraceExportClient(OtlpExporterOptions options, OtlpCollector.Trac
         /// <inheritdoc/>
         public override bool SendExportRequest(OtlpCollector.ExportTraceServiceRequest request, CancellationToken cancellationToken = default)
         {
-            var deadline = DateTime.UtcNow.AddMilliseconds(this.Options.TimeoutMilliseconds);
+            var deadline = DateTime.UtcNow.AddMilliseconds(this.TimeoutMilliseconds);
 
             try
             {
@@ -51,7 +51,7 @@ public override bool SendExportRequest(OtlpCollector.ExportTraceServiceRequest r
             }
             catch (RpcException ex)
             {
-                OpenTelemetryProtocolExporterEventSource.Log.FailedToReachCollector(this.Options.Endpoint, ex);
+                OpenTelemetryProtocolExporterEventSource.Log.FailedToReachCollector(this.Endpoint, ex);
 
                 return false;
             }
diff --git a/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/Implementation/ExportClient/OtlpHttpMetricsExportClient.cs b/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/Implementation/ExportClient/OtlpHttpMetricsExportClient.cs
index 541e32f1b87..9be1ce51d50 100644
--- a/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/Implementation/ExportClient/OtlpHttpMetricsExportClient.cs
+++ b/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/Implementation/ExportClient/OtlpHttpMetricsExportClient.cs
@@ -38,7 +38,7 @@ internal sealed class OtlpHttpMetricsExportClient : BaseOtlpHttpExportClient<Otl
         public OtlpHttpMetricsExportClient(OtlpExporterOptions options, HttpClient httpClient)
             : base(options, httpClient)
         {
-            this.exportMetricsUri = this.Options.Endpoint;
+            this.exportMetricsUri = this.Endpoint;
         }
 
         protected override HttpRequestMessage CreateHttpRequest(OtlpCollector.ExportMetricsServiceRequest exportRequest)
diff --git a/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/Implementation/ExportClient/OtlpHttpTraceExportClient.cs b/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/Implementation/ExportClient/OtlpHttpTraceExportClient.cs
index 7a769433211..825ecdf6cca 100644
--- a/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/Implementation/ExportClient/OtlpHttpTraceExportClient.cs
+++ b/src/OpenTelemetry.Exporter.OpenTelemetryProtocol/Implementation/ExportClient/OtlpHttpTraceExportClient.cs
@@ -38,7 +38,7 @@ internal sealed class OtlpHttpTraceExportClient : BaseOtlpHttpExportClient<OtlpC
         public OtlpHttpTraceExportClient(OtlpExporterOptions options, HttpClient httpClient)
             : base(options, httpClient)
         {
-            this.exportTracesUri = this.Options.Endpoint;
+            this.exportTracesUri = this.Endpoint;
         }
 
         protected override HttpRequestMessage CreateHttpRequest(OtlpCollector.ExportTraceServiceRequest exportRequest)