diff --git a/CHANGELOG.md b/CHANGELOG.md
index a84359118f2..c94e7f322f5 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -10,6 +10,9 @@ release.
 - Remove spaces from example exporter User-Agent header to conform to RFC7231 & RFC7230.
   [#3052](https://github.com/open-telemetry/opentelemetry-specification/pull/3052)
 
+- Add Cloud Spanner and Microsoft SQL Server Compact to db.system semantic conventions.
+  [#3105](https://github.com/open-telemetry/opentelemetry-specification/pull/3105)
+
 ### Context
 
 ### Traces
diff --git a/semantic_conventions/trace/database.yaml b/semantic_conventions/trace/database.yaml
index 737c2459bb4..c8d6bb049f4 100644
--- a/semantic_conventions/trace/database.yaml
+++ b/semantic_conventions/trace/database.yaml
@@ -163,6 +163,9 @@ groups:
             - id: spanner
               value: 'spanner'
               brief: 'Cloud Spanner'
+            - id: mssqlcompact
+              value: 'mssqlcompact'
+              brief: 'Microsoft SQL Server Compact'
       - id: connection_string
         tag: connection-level
         type: string
diff --git a/specification/trace/semantic_conventions/database.md b/specification/trace/semantic_conventions/database.md
index 5453c611053..17fea4c807a 100644
--- a/specification/trace/semantic_conventions/database.md
+++ b/specification/trace/semantic_conventions/database.md
@@ -6,10 +6,16 @@
 
 <!-- toc -->
 
-- [Semantic conventions for database client calls](#semantic-conventions-for-database-client-calls)
-  - [Connection-level attributes](#connection-level-attributes)
-  - [Call-level attributes](#call-level-attributes)
-  - [Examples](#examples)
+- [Connection-level attributes](#connection-level-attributes)
+  * [Notes and well-known identifiers for `db.system`](#notes-and-well-known-identifiers-for-dbsystem)
+  * [Connection-level attributes for specific technologies](#connection-level-attributes-for-specific-technologies)
+- [Call-level attributes](#call-level-attributes)
+  * [Call-level attributes for specific technologies](#call-level-attributes-for-specific-technologies)
+    + [Cassandra](#cassandra)
+- [Examples](#examples)
+  * [MySQL](#mysql)
+  * [Redis](#redis)
+  * [MongoDB](#mongodb)
 
 <!-- tocstop -->
 
@@ -112,6 +118,7 @@ Some database systems may allow a connection to switch to a different `db.user`,
 | `opensearch` | OpenSearch |
 | `clickhouse` | ClickHouse |
 | `spanner` | Cloud Spanner |
+| `mssqlcompact` | Microsoft SQL Server Compact |
 <!-- endsemconv -->
 
 ### Notes and well-known identifiers for `db.system`