diff --git a/src/targeting.js b/src/targeting.js
index 0ca9f949a64..ae54cf26bf6 100644
--- a/src/targeting.js
+++ b/src/targeting.js
@@ -210,7 +210,13 @@ export function newTargeting(auctionManager) {
         // setKeywords supports string and array as value
         if (utils.isStr(astTargeting[targetId][key]) || utils.isArray(astTargeting[targetId][key])) {
           let keywordsObj = {};
-          keywordsObj[key.toUpperCase()] = astTargeting[targetId][key];
+          let regex = /pt[0-9]/;
+          if (key.search(regex) < 0) {
+            keywordsObj[key.toUpperCase()] = astTargeting[targetId][key];
+          } else {
+            // pt${n} keys should not be uppercased
+            keywordsObj[key] = astTargeting[targetId][key];
+          }
           window.apntag.setKeywords(targetId, keywordsObj);
         }
       })
diff --git a/test/spec/unit/pbjs_api_spec.js b/test/spec/unit/pbjs_api_spec.js
index 4c72917d7a7..826f3fdc8f0 100644
--- a/test/spec/unit/pbjs_api_spec.js
+++ b/test/spec/unit/pbjs_api_spec.js
@@ -1812,7 +1812,10 @@ describe('Unit: Prebid Module', function () {
       resetAuction();
       auctionManagerInstance = newAuctionManager();
       sinon.stub(auctionManagerInstance, 'getBidsReceived').callsFake(function() {
-        return [getBidResponses()[1]];
+        let bidResponse = getBidResponses()[1];
+        // add a pt0 value for special case.
+        bidResponse.adserverTargeting.pt0 = 'someVal';
+        return [bidResponse];
       });
       sinon.stub(auctionManagerInstance, 'getAdUnitCodes').callsFake(function() {
         return ['/19968336/header-bid-tag-0'];
@@ -1832,10 +1835,15 @@ describe('Unit: Prebid Module', function () {
 
       var expectedAdserverTargeting = bids[0].adserverTargeting;
       var newAdserverTargeting = {};
+      let regex = /pt[0-9]/;
+
       for (var key in expectedAdserverTargeting) {
-        newAdserverTargeting[key.toUpperCase()] = expectedAdserverTargeting[key];
+        if (key.search(regex) < 0) {
+          newAdserverTargeting[key.toUpperCase()] = expectedAdserverTargeting[key];
+        } else {
+          newAdserverTargeting[key] = expectedAdserverTargeting[key];
+        }
       }
-
       targeting.setTargetingForAst();
       expect(newAdserverTargeting).to.deep.equal(window.apntag.tags[adUnitCode].keywords);
     });