diff --git a/src/adaptermanager.js b/src/adaptermanager.js
index 0dc5a9177db..7f63a950283 100644
--- a/src/adaptermanager.js
+++ b/src/adaptermanager.js
@@ -179,7 +179,6 @@ exports.makeBidRequests = function(adUnits, auctionStart, auctionId, cbTimeout,
         auctionId,
         bidderRequestId,
         tid,
-        adUnitsS2SCopy,
         bids: getBids({bidderCode, auctionId, bidderRequestId, 'adUnits': adUnitsS2SCopy, labels}),
         auctionStart: auctionStart,
         timeout: _s2sConfig.timeout,
@@ -189,6 +188,21 @@ exports.makeBidRequests = function(adUnits, auctionStart, auctionId, cbTimeout,
         bidRequests.push(bidderRequest);
       }
     });
+
+    // update the s2sAdUnits object and remove all bids that didn't pass sizeConfig/label checks from getBids()
+    // this is to keep consistency and only allow bids/adunits that passed the checks to go to pbs
+    adUnitsS2SCopy.forEach((adUnitCopy) => {
+      let validBids = adUnitCopy.bids.filter((adUnitBid) => {
+        return find(bidRequests, request => {
+          return find(request.bids, (reqBid) => reqBid.bidId === adUnitBid.bid_id);
+        });
+      });
+      adUnitCopy.bids = validBids;
+    });
+
+    bidRequests.forEach(request => {
+      request.adUnitsS2SCopy = adUnitsS2SCopy.filter(adUnitCopy => adUnitCopy.bids.length > 0);
+    });
   }
 
   // client adapters
@@ -301,17 +315,6 @@ exports.callBids = (adUnits, bidRequests, addBidResponse, doneCb, requestCallbac
     const s2sAdapter = _bidderRegistry[_s2sConfig.adapter];
     let tid = serverBidRequests[0].tid;
     let adUnitsS2SCopy = serverBidRequests[0].adUnitsS2SCopy;
-    adUnitsS2SCopy.forEach((adUnitCopy) => {
-      let validBids = adUnitCopy.bids.filter((bid) => {
-        return find(serverBidRequests, request => {
-          return request.bidderCode === bid.bidder &&
-          find(request.bids, (reqBid) => reqBid.adUnitCode === adUnitCopy.code);
-        });
-      });
-      adUnitCopy.bids = validBids;
-    });
-
-    adUnitsS2SCopy = adUnitsS2SCopy.filter(adUnitCopy => adUnitCopy.bids.length > 0);
 
     if (s2sAdapter) {
       let s2sBidRequest = {tid, 'ad_units': adUnitsS2SCopy};
diff --git a/test/spec/unit/core/adapterManager_spec.js b/test/spec/unit/core/adapterManager_spec.js
index 9050a0871df..51b34f8d1b8 100644
--- a/test/spec/unit/core/adapterManager_spec.js
+++ b/test/spec/unit/core/adapterManager_spec.js
@@ -191,7 +191,7 @@ describe('adapterManager tests', () => {
                 'auctionId': '1ff753bd4ae5cb',
                 'startTime': 1463510220995,
                 'status': 1,
-                'bid_id': '378a8914450b334'
+                'bid_id': '68136e1c47023d'
               }
             ]
           },
@@ -228,7 +228,7 @@ describe('adapterManager tests', () => {
                 'bidderRequestId': '55e24a66bed717',
                 'auctionId': '1ff753bd4ae5cb',
                 'startTime': 1463510220996,
-                'bid_id': '387d9d9c32ca47c'
+                'bid_id': '7e5d6af25ed188'
               }
             ]
           }
@@ -792,6 +792,7 @@ describe('adapterManager tests', () => {
 
       afterEach(() => {
         matchMedia.restore();
+        config.resetConfig();
         setSizeConfig([]);
       });
 
@@ -887,6 +888,33 @@ describe('adapterManager tests', () => {
         expect(bidRequests[0].bids.length).to.equal(1);
         expect(bidRequests[0].bids[0].adUnitCode).to.equal(adUnits[1].code);
       });
+
+      it('should filter adUnits/bidders based on applid labels for s2s requests', () => {
+        adUnits[0].labelAll = ['visitor-uk', 'mobile'];
+        adUnits[1].labelAny = ['visitor-uk', 'desktop'];
+        adUnits[1].bids[0].labelAny = ['mobile'];
+        adUnits[1].bids[1].labelAll = ['desktop'];
+
+        let TESTING_CONFIG = utils.deepClone(CONFIG);
+        TESTING_CONFIG.bidders = ['appnexus', 'rubicon'];
+        config.setConfig({ s2sConfig: TESTING_CONFIG });
+
+        let bidRequests = AdapterManager.makeBidRequests(
+          adUnits,
+          Date.now(),
+          utils.getUniqueIdentifierStr(),
+          function callback() {},
+          ['visitor-uk', 'desktop']
+        );
+
+        expect(bidRequests.length).to.equal(1);
+        expect(bidRequests[0].adUnitsS2SCopy.length).to.equal(1);
+        expect(bidRequests[0].adUnitsS2SCopy[0].bids.length).to.equal(1);
+        expect(bidRequests[0].adUnitsS2SCopy[0].bids[0].bidder).to.equal('rubicon');
+        expect(bidRequests[0].adUnitsS2SCopy[0].bids[0].placementCode).to.equal(adUnits[1].code);
+        expect(bidRequests[0].adUnitsS2SCopy[0].bids[0].bid_id).to.equal(bidRequests[0].bids[0].bid_id);
+        expect(bidRequests[0].adUnitsS2SCopy[0].labelAny).to.deep.equal(['visitor-uk', 'desktop']);
+      });
     });
 
     describe('gdpr consent module', () => {