diff --git a/news/8733.bugfix b/news/8733.bugfix
new file mode 100644
index 00000000000..027e85f6496
--- /dev/null
+++ b/news/8733.bugfix
@@ -0,0 +1 @@
+Correctly uninstall console scripts installed to ~/.local/bin
diff --git a/src/pip/_internal/locations.py b/src/pip/_internal/locations.py
index 0c1235488d6..0984a11cef1 100644
--- a/src/pip/_internal/locations.py
+++ b/src/pip/_internal/locations.py
@@ -72,19 +72,27 @@ def get_src_prefix():
     # Use getusersitepackages if this is present, as it ensures that the
     # value is initialised properly.
     user_site = site.getusersitepackages()
+    user_base = site.getuserbase()
 except AttributeError:
     user_site = site.USER_SITE
+    user_base = site.USER_BASE
 
 if WINDOWS:
     bin_py = os.path.join(sys.prefix, 'Scripts')
-    bin_user = os.path.join(user_site, 'Scripts')
+    if running_under_virtualenv():
+        bin_user = os.path.join(user_site, 'Scripts')
+    else:
+        bin_user = os.path.join(user_base, 'Scripts')
     # buildout uses 'bin' on Windows too?
     if not os.path.exists(bin_py):
         bin_py = os.path.join(sys.prefix, 'bin')
         bin_user = os.path.join(user_site, 'bin')
 else:
     bin_py = os.path.join(sys.prefix, 'bin')
-    bin_user = os.path.join(user_site, 'bin')
+    if running_under_virtualenv():
+        bin_user = os.path.join(user_site, 'bin')
+    else:
+        bin_user = os.path.join(user_base, 'bin')
 
     # Forcing to use /usr/local/bin for standard macOS framework installs
     # Also log to ~/Library/Logs/ for use with the Console.app log viewer