diff --git a/Lib/pathlib.py b/Lib/pathlib.py
index 87c2e970a0a881..a57b582a211e06 100644
--- a/Lib/pathlib.py
+++ b/Lib/pathlib.py
@@ -235,7 +235,7 @@ def __repr__(self):
         return "<{}.parents>".format(type(self._path).__name__)
 
 
-class PurePath(os.PathLike):
+class PurePath:
     """Base class for manipulating paths without I/O.
 
     PurePath represents a filesystem path and offers operations which
@@ -715,6 +715,10 @@ def match(self, path_pattern, *, case_sensitive=None):
                 return False
         return True
 
+# Subclassing os.PathLike makes isinstance() checks slower,
+# which in turn makes Path construction slower. Register instead!
+os.PathLike.register(PurePath)
+
 
 class PurePosixPath(PurePath):
     """PurePath subclass for non-Windows systems.