diff --git a/Modules/Setup.stdlib.in b/Modules/Setup.stdlib.in
index fdd20d4d6217b6..8ab93704765a5c 100644
--- a/Modules/Setup.stdlib.in
+++ b/Modules/Setup.stdlib.in
@@ -40,7 +40,7 @@
 @MODULE__QUEUE_TRUE@_queue _queuemodule.c
 @MODULE__RANDOM_TRUE@_random _randommodule.c
 @MODULE__TYPING_TRUE@_typing _typingmodule.c
-@MODULE__XXSUBINTERPRETERS_TRUE@_xxsubinterpreters __xxsubinterpretersmodule.c
+@MODULE__XXSUBINTERPRETERS_TRUE@_xxsubinterpreters _xxsubinterpretersmodule.c
 @MODULE__ZONEINFO_TRUE@_zoneinfo _zoneinfo.c
 
 # needs libm
@@ -98,6 +98,9 @@
 @MODULE_FCNTL_TRUE@fcntl fcntlmodule.c
 @MODULE_GRP_TRUE@grp grpmodule.c
 @MODULE_MMAP_TRUE@mmap mmapmodule.c
+# FreeBSD: nis/yp APIs are in libc
+# Linux: glibc has deprecated SUN RPC, APIs are in libnsl and libtirpc (bpo-32521)
+@MODULE_NIS_TRUE@nis nismodule.c
 # needs sys/soundcard.h or linux/soundcard.h (Linux, FreeBSD)
 @MODULE_OSSAUDIODEV_TRUE@ossaudiodev ossaudiodev.c
 @MODULE_RESOURCE_TRUE@resource resource.c
diff --git a/configure b/configure
index 08407270580426..dd2e3b8ff4d765 100755
--- a/configure
+++ b/configure
@@ -648,6 +648,8 @@ MODULE_ZLIB_FALSE
 MODULE_ZLIB_TRUE
 MODULE__SQLITE3_FALSE
 MODULE__SQLITE3_TRUE
+MODULE_NIS_FALSE
+MODULE_NIS_TRUE
 MODULE__DECIMAL_FALSE
 MODULE__DECIMAL_TRUE
 MODULE__BLAKE2_FALSE
@@ -787,6 +789,8 @@ TCLTK_LIBS
 TCLTK_INCLUDES
 LIBSQLITE3_LIBS
 LIBSQLITE3_CFLAGS
+LIBNSL_LIBS
+LIBNSL_CFLAGS
 LIBMPDEC_INTERNAL
 LIBMPDEC_LDFLAGS
 LIBMPDEC_CFLAGS
@@ -1014,6 +1018,8 @@ LIBS
 CPPFLAGS
 CPP
 PROFILE_TASK
+LIBNSL_CFLAGS
+LIBNSL_LIBS
 LIBSQLITE3_CFLAGS
 LIBSQLITE3_LIBS
 ZLIB_CFLAGS
@@ -1795,6 +1801,9 @@ Some influential environment variables:
   CPP         C preprocessor
   PROFILE_TASK
               Python args for PGO generation task
+  LIBNSL_CFLAGS
+              C compiler flags for LIBNSL, overriding pkg-config
+  LIBNSL_LIBS linker flags for LIBNSL, overriding pkg-config
   LIBSQLITE3_CFLAGS
               C compiler flags for LIBSQLITE3, overriding pkg-config
   LIBSQLITE3_LIBS
@@ -11071,6 +11080,274 @@ if test "$have_glibc_memmove_bug" = yes; then
 fi
 
 
+
+pkg_failed=no
+{ $as_echo "$as_me:${as_lineno-$LINENO}: checking for LIBNSL" >&5
+$as_echo_n "checking for LIBNSL... " >&6; }
+
+if test -n "$LIBNSL_CFLAGS"; then
+    pkg_cv_LIBNSL_CFLAGS="$LIBNSL_CFLAGS"
+ elif test -n "$PKG_CONFIG"; then
+    if test -n "$PKG_CONFIG" && \
+    { { $as_echo "$as_me:${as_lineno-$LINENO}: \$PKG_CONFIG --exists --print-errors \"libnsl\""; } >&5
+  ($PKG_CONFIG --exists --print-errors "libnsl") 2>&5
+  ac_status=$?
+  $as_echo "$as_me:${as_lineno-$LINENO}: \$? = $ac_status" >&5
+  test $ac_status = 0; }; then
+  pkg_cv_LIBNSL_CFLAGS=`$PKG_CONFIG --cflags "libnsl" 2>/dev/null`
+		      test "x$?" != "x0" && pkg_failed=yes
+else
+  pkg_failed=yes
+fi
+ else
+    pkg_failed=untried
+fi
+if test -n "$LIBNSL_LIBS"; then
+    pkg_cv_LIBNSL_LIBS="$LIBNSL_LIBS"
+ elif test -n "$PKG_CONFIG"; then
+    if test -n "$PKG_CONFIG" && \
+    { { $as_echo "$as_me:${as_lineno-$LINENO}: \$PKG_CONFIG --exists --print-errors \"libnsl\""; } >&5
+  ($PKG_CONFIG --exists --print-errors "libnsl") 2>&5
+  ac_status=$?
+  $as_echo "$as_me:${as_lineno-$LINENO}: \$? = $ac_status" >&5
+  test $ac_status = 0; }; then
+  pkg_cv_LIBNSL_LIBS=`$PKG_CONFIG --libs "libnsl" 2>/dev/null`
+		      test "x$?" != "x0" && pkg_failed=yes
+else
+  pkg_failed=yes
+fi
+ else
+    pkg_failed=untried
+fi
+
+
+
+if test $pkg_failed = yes; then
+   	{ $as_echo "$as_me:${as_lineno-$LINENO}: result: no" >&5
+$as_echo "no" >&6; }
+
+if $PKG_CONFIG --atleast-pkgconfig-version 0.20; then
+        _pkg_short_errors_supported=yes
+else
+        _pkg_short_errors_supported=no
+fi
+        if test $_pkg_short_errors_supported = yes; then
+	        LIBNSL_PKG_ERRORS=`$PKG_CONFIG --short-errors --print-errors --cflags --libs "libnsl" 2>&1`
+        else
+	        LIBNSL_PKG_ERRORS=`$PKG_CONFIG --print-errors --cflags --libs "libnsl" 2>&1`
+        fi
+	# Put the nasty error message in config.log where it belongs
+	echo "$LIBNSL_PKG_ERRORS" >&5
+
+
+  LIBNSL_CFLAGS=
+  save_CFLAGS=$CFLAGS
+save_CPPFLAGS=$CPPFLAGS
+save_LDFLAGS=$LDFLAGS
+save_LIBS=$LIBS
+
+
+    { $as_echo "$as_me:${as_lineno-$LINENO}: checking for library containing yp_match" >&5
+$as_echo_n "checking for library containing yp_match... " >&6; }
+if ${ac_cv_search_yp_match+:} false; then :
+  $as_echo_n "(cached) " >&6
+else
+  ac_func_search_save_LIBS=$LIBS
+cat confdefs.h - <<_ACEOF >conftest.$ac_ext
+/* end confdefs.h.  */
+
+/* Override any GCC internal prototype to avoid an error.
+   Use char because int might match the return type of a GCC
+   builtin and then its argument prototype would still apply.  */
+#ifdef __cplusplus
+extern "C"
+#endif
+char yp_match ();
+int
+main ()
+{
+return yp_match ();
+  ;
+  return 0;
+}
+_ACEOF
+for ac_lib in '' nsl; do
+  if test -z "$ac_lib"; then
+    ac_res="none required"
+  else
+    ac_res=-l$ac_lib
+    LIBS="-l$ac_lib  $ac_func_search_save_LIBS"
+  fi
+  if ac_fn_c_try_link "$LINENO"; then :
+  ac_cv_search_yp_match=$ac_res
+fi
+rm -f core conftest.err conftest.$ac_objext \
+    conftest$ac_exeext
+  if ${ac_cv_search_yp_match+:} false; then :
+  break
+fi
+done
+if ${ac_cv_search_yp_match+:} false; then :
+
+else
+  ac_cv_search_yp_match=no
+fi
+rm conftest.$ac_ext
+LIBS=$ac_func_search_save_LIBS
+fi
+{ $as_echo "$as_me:${as_lineno-$LINENO}: result: $ac_cv_search_yp_match" >&5
+$as_echo "$ac_cv_search_yp_match" >&6; }
+ac_res=$ac_cv_search_yp_match
+if test "$ac_res" != no; then :
+  test "$ac_res" = "none required" || LIBS="$ac_res $LIBS"
+  have_nis=yes
+else
+  have_nis=no
+fi
+
+
+CFLAGS=$save_CFLAGS
+CPPFLAGS=$save_CPPFLAGS
+LDFLAGS=$save_LDFLAGS
+LIBS=$save_LIBS
+
+
+  case $ac_cv_search_yp_match in #(
+  no) :
+    LIBNSL_LIBS= ;; #(
+  "none required") :
+    LIBNSL_LIBS= ;; #(
+  *) :
+    LIBNSL_LIBS=$ac_cv_search_yp_match
+   ;;
+esac
+
+elif test $pkg_failed = untried; then
+     	{ $as_echo "$as_me:${as_lineno-$LINENO}: result: no" >&5
+$as_echo "no" >&6; }
+
+  LIBNSL_CFLAGS=
+  save_CFLAGS=$CFLAGS
+save_CPPFLAGS=$CPPFLAGS
+save_LDFLAGS=$LDFLAGS
+save_LIBS=$LIBS
+
+
+    { $as_echo "$as_me:${as_lineno-$LINENO}: checking for library containing yp_match" >&5
+$as_echo_n "checking for library containing yp_match... " >&6; }
+if ${ac_cv_search_yp_match+:} false; then :
+  $as_echo_n "(cached) " >&6
+else
+  ac_func_search_save_LIBS=$LIBS
+cat confdefs.h - <<_ACEOF >conftest.$ac_ext
+/* end confdefs.h.  */
+
+/* Override any GCC internal prototype to avoid an error.
+   Use char because int might match the return type of a GCC
+   builtin and then its argument prototype would still apply.  */
+#ifdef __cplusplus
+extern "C"
+#endif
+char yp_match ();
+int
+main ()
+{
+return yp_match ();
+  ;
+  return 0;
+}
+_ACEOF
+for ac_lib in '' nsl; do
+  if test -z "$ac_lib"; then
+    ac_res="none required"
+  else
+    ac_res=-l$ac_lib
+    LIBS="-l$ac_lib  $ac_func_search_save_LIBS"
+  fi
+  if ac_fn_c_try_link "$LINENO"; then :
+  ac_cv_search_yp_match=$ac_res
+fi
+rm -f core conftest.err conftest.$ac_objext \
+    conftest$ac_exeext
+  if ${ac_cv_search_yp_match+:} false; then :
+  break
+fi
+done
+if ${ac_cv_search_yp_match+:} false; then :
+
+else
+  ac_cv_search_yp_match=no
+fi
+rm conftest.$ac_ext
+LIBS=$ac_func_search_save_LIBS
+fi
+{ $as_echo "$as_me:${as_lineno-$LINENO}: result: $ac_cv_search_yp_match" >&5
+$as_echo "$ac_cv_search_yp_match" >&6; }
+ac_res=$ac_cv_search_yp_match
+if test "$ac_res" != no; then :
+  test "$ac_res" = "none required" || LIBS="$ac_res $LIBS"
+  have_nis=yes
+else
+  have_nis=no
+fi
+
+
+CFLAGS=$save_CFLAGS
+CPPFLAGS=$save_CPPFLAGS
+LDFLAGS=$save_LDFLAGS
+LIBS=$save_LIBS
+
+
+  case $ac_cv_search_yp_match in #(
+  no) :
+    LIBNSL_LIBS= ;; #(
+  "none required") :
+    LIBNSL_LIBS= ;; #(
+  *) :
+    LIBNSL_LIBS=$ac_cv_search_yp_match
+   ;;
+esac
+
+else
+	LIBNSL_CFLAGS=$pkg_cv_LIBNSL_CFLAGS
+	LIBNSL_LIBS=$pkg_cv_LIBNSL_LIBS
+        { $as_echo "$as_me:${as_lineno-$LINENO}: result: yes" >&5
+$as_echo "yes" >&6; }
+	have_nis=yes
+fi
+
+if test "x$have_nis" = xyes; then :
+
+  save_CFLAGS=$CFLAGS
+save_CPPFLAGS=$CPPFLAGS
+save_LDFLAGS=$LDFLAGS
+save_LIBS=$LIBS
+
+
+    CPPFLAGS="$LIBNSL_CFLAGS $CFLAGS"
+    for ac_header in rpc/rpc.h
+do :
+  ac_fn_c_check_header_mongrel "$LINENO" "rpc/rpc.h" "ac_cv_header_rpc_rpc_h" "$ac_includes_default"
+if test "x$ac_cv_header_rpc_rpc_h" = xyes; then :
+  cat >>confdefs.h <<_ACEOF
+#define HAVE_RPC_RPC_H 1
+_ACEOF
+
+fi
+
+done
+
+
+CFLAGS=$save_CFLAGS
+CPPFLAGS=$save_CPPFLAGS
+LDFLAGS=$save_LDFLAGS
+LIBS=$save_LIBS
+
+
+
+fi
+
+
 pkg_failed=no
 { $as_echo "$as_me:${as_lineno-$LINENO}: checking for LIBSQLITE3" >&5
 $as_echo_n "checking for LIBSQLITE3... " >&6; }
@@ -21068,6 +21345,42 @@ fi
 $as_echo "$py_cv_module__decimal" >&6; }
 
 
+  { $as_echo "$as_me:${as_lineno-$LINENO}: checking for stdlib extension module nis" >&5
+$as_echo_n "checking for stdlib extension module nis... " >&6; }
+      case $py_stdlib_not_available in #(
+  *nis*) :
+    py_cv_module_nis=n/a ;; #(
+  *) :
+    if true; then :
+  if test "$have_nis" = yes -a "$ac_cv_header_rpc_rpc_h" = yes; then :
+  py_cv_module_nis=yes
+else
+  py_cv_module_nis=missing
+fi
+else
+  py_cv_module_nis=disabled
+fi
+   ;;
+esac
+  as_fn_append MODULE_BLOCK "MODULE_NIS=$py_cv_module_nis$as_nl"
+  if test "x$py_cv_module_nis" = xyes; then :
+
+    as_fn_append MODULE_BLOCK "MODULE_NIS_CFLAGS=$LIBNSL_CFLAGS$as_nl"
+    as_fn_append MODULE_BLOCK "MODULE_NIS_LDFLAGS=$LIBNSL_LIBS$as_nl"
+
+fi
+   if test "$py_cv_module_nis" = yes; then
+  MODULE_NIS_TRUE=
+  MODULE_NIS_FALSE='#'
+else
+  MODULE_NIS_TRUE='#'
+  MODULE_NIS_FALSE=
+fi
+
+  { $as_echo "$as_me:${as_lineno-$LINENO}: result: $py_cv_module_nis" >&5
+$as_echo "$py_cv_module_nis" >&6; }
+
+
   { $as_echo "$as_me:${as_lineno-$LINENO}: checking for stdlib extension module _sqlite3" >&5
 $as_echo_n "checking for stdlib extension module _sqlite3... " >&6; }
       case $py_stdlib_not_available in #(
@@ -21787,6 +22100,10 @@ if test -z "${MODULE__DECIMAL_TRUE}" && test -z "${MODULE__DECIMAL_FALSE}"; then
   as_fn_error $? "conditional \"MODULE__DECIMAL\" was never defined.
 Usually this means the macro was only invoked conditionally." "$LINENO" 5
 fi
+if test -z "${MODULE_NIS_TRUE}" && test -z "${MODULE_NIS_FALSE}"; then
+  as_fn_error $? "conditional \"MODULE_NIS\" was never defined.
+Usually this means the macro was only invoked conditionally." "$LINENO" 5
+fi
 if test -z "${MODULE__SQLITE3_TRUE}" && test -z "${MODULE__SQLITE3_FALSE}"; then
   as_fn_error $? "conditional \"MODULE__SQLITE3\" was never defined.
 Usually this means the macro was only invoked conditionally." "$LINENO" 5
diff --git a/configure.ac b/configure.ac
index 05992dc28f4d19..72f2def9b11af0 100644
--- a/configure.ac
+++ b/configure.ac
@@ -3191,6 +3191,28 @@ if test "$have_glibc_memmove_bug" = yes; then
     AS_VAR_APPEND([LIBMPDEC_CFLAGS], [" -U_FORTIFY_SOURCE"])
 fi
 
+
+dnl check for NIS / libnsl dependencies
+dnl libnsl dependencies include tirpc includes and lib
+PKG_CHECK_MODULES([LIBNSL], [libnsl], [have_nis=yes], [
+  LIBNSL_CFLAGS=
+  WITH_SAVE_ENV([
+    AC_SEARCH_LIBS([yp_match], [nsl], [have_nis=yes], [have_nis=no])
+  ])
+  AS_CASE([$ac_cv_search_yp_match],
+    [no], [LIBNSL_LIBS=],
+    ["none required"], [LIBNSL_LIBS=],
+    [LIBNSL_LIBS=$ac_cv_search_yp_match]
+  )
+])
+
+AS_VAR_IF([have_nis], [yes], [
+  WITH_SAVE_ENV([
+    CPPFLAGS="$LIBNSL_CFLAGS $CFLAGS"
+    AC_CHECK_HEADERS([rpc/rpc.h])
+  ])
+])
+
 dnl Check for SQLite library. Use pkg-config if available.
 PKG_CHECK_MODULES(
   [LIBSQLITE3], [sqlite3 >= 3.7.15], [], [
@@ -6166,6 +6188,9 @@ PY_STDLIB_MOD([_sha3], [test "$with_builtin_sha3" = yes])
 PY_STDLIB_MOD([_blake2], [test "$with_builtin_blake2" = yes])
 
 PY_STDLIB_MOD([_decimal], [], [], [$LIBMPDEC_CFLAGS], [$LIBMPDEC_LDFLAGS])
+PY_STDLIB_MOD([nis],
+  [], [test "$have_nis" = yes -a "$ac_cv_header_rpc_rpc_h" = yes],
+  [$LIBNSL_CFLAGS], [$LIBNSL_LIBS])
 PY_STDLIB_MOD([_sqlite3],
   [test "$have_sqlite3" = "yes"],
   [test "$have_supported_sqlite3" = "yes"],
diff --git a/pyconfig.h.in b/pyconfig.h.in
index 6672344437cddd..c9c58656f58ac4 100644
--- a/pyconfig.h.in
+++ b/pyconfig.h.in
@@ -896,6 +896,9 @@
 /* Define if you have readline 4.0 */
 #undef HAVE_RL_RESIZE_TERMINAL
 
+/* Define to 1 if you have the <rpc/rpc.h> header file. */
+#undef HAVE_RPC_RPC_H
+
 /* Define to 1 if you have the `rtpSpawn' function. */
 #undef HAVE_RTPSPAWN
 
diff --git a/setup.py b/setup.py
index b9b48b2f74ba0c..dd1a3df60bfdf1 100644
--- a/setup.py
+++ b/setup.py
@@ -1993,49 +1993,7 @@ def detect_hash_builtins(self):
         ))
 
     def detect_nis(self):
-        if MS_WINDOWS or CYGWIN or HOST_PLATFORM == 'qnx6':
-            self.missing.append('nis')
-            return
-
-        libs = []
-        library_dirs = []
-        includes_dirs = []
-
-        # bpo-32521: glibc has deprecated Sun RPC for some time. Fedora 28
-        # moved headers and libraries to libtirpc and libnsl. The headers
-        # are in tircp and nsl sub directories.
-        rpcsvc_inc = find_file(
-            'rpcsvc/yp_prot.h', self.inc_dirs,
-            [os.path.join(inc_dir, 'nsl') for inc_dir in self.inc_dirs]
-        )
-        rpc_inc = find_file(
-            'rpc/rpc.h', self.inc_dirs,
-            [os.path.join(inc_dir, 'tirpc') for inc_dir in self.inc_dirs]
-        )
-        if rpcsvc_inc is None or rpc_inc is None:
-            # not found
-            self.missing.append('nis')
-            return
-        includes_dirs.extend(rpcsvc_inc)
-        includes_dirs.extend(rpc_inc)
-
-        if self.compiler.find_library_file(self.lib_dirs, 'nsl'):
-            libs.append('nsl')
-        else:
-            # libnsl-devel: check for libnsl in nsl/ subdirectory
-            nsl_dirs = [os.path.join(lib_dir, 'nsl') for lib_dir in self.lib_dirs]
-            libnsl = self.compiler.find_library_file(nsl_dirs, 'nsl')
-            if libnsl is not None:
-                library_dirs.append(os.path.dirname(libnsl))
-                libs.append('nsl')
-
-        if self.compiler.find_library_file(self.lib_dirs, 'tirpc'):
-            libs.append('tirpc')
-
-        self.add(Extension('nis', ['nismodule.c'],
-                           libraries=libs,
-                           library_dirs=library_dirs,
-                           include_dirs=includes_dirs))
+        self.addext(Extension('nis', ['nismodule.c']))
 
 
 class PyBuildInstall(install):