diff --git a/quantum/keyboard.c b/quantum/keyboard.c
index f8e36994d298..030fec2d3e99 100644
--- a/quantum/keyboard.c
+++ b/quantum/keyboard.c
@@ -40,9 +40,6 @@ along with this program.  If not, see <http://www.gnu.org/licenses/>.
 #ifdef PS2_MOUSE_ENABLE
 #    include "ps2_mouse.h"
 #endif
-#ifdef SERIAL_MOUSE_ENABLE
-#    include "serial_mouse.h"
-#endif
 #ifdef RGBLIGHT_ENABLE
 #    include "rgblight.h"
 #endif
@@ -310,9 +307,6 @@ void keyboard_init(void) {
 #ifdef PS2_MOUSE_ENABLE
     ps2_mouse_init();
 #endif
-#ifdef SERIAL_MOUSE_ENABLE
-    serial_mouse_init();
-#endif
 #ifdef BACKLIGHT_ENABLE
     backlight_init();
 #endif
@@ -490,10 +484,6 @@ void keyboard_task(void) {
     ps2_mouse_task();
 #endif
 
-#ifdef SERIAL_MOUSE_ENABLE
-    serial_mouse_task();
-#endif
-
 #ifdef POINTING_DEVICE_ENABLE
     pointing_device_task();
 #endif
diff --git a/tmk_core/protocol.mk b/tmk_core/protocol.mk
index 8aa063c9116c..d4ad50db6a75 100644
--- a/tmk_core/protocol.mk
+++ b/tmk_core/protocol.mk
@@ -1,25 +1,5 @@
 PROTOCOL_DIR = protocol
 
-ifeq ($(strip $(SERIAL_MOUSE_MICROSOFT_ENABLE)), yes)
-    SRC += $(PROTOCOL_DIR)/serial_mouse_microsoft.c
-    OPT_DEFS += -DSERIAL_MOUSE_ENABLE -DSERIAL_MOUSE_MICROSOFT \
-                -DMOUSE_ENABLE
-endif
-
-ifeq ($(strip $(SERIAL_MOUSE_MOUSESYSTEMS_ENABLE)), yes)
-    SRC += $(PROTOCOL_DIR)/serial_mouse_mousesystems.c
-    OPT_DEFS += -DSERIAL_MOUSE_ENABLE -DSERIAL_MOUSE_MOUSESYSTEMS \
-                -DMOUSE_ENABLE
-endif
-
-ifeq ($(strip $(SERIAL_MOUSE_USE_SOFT)), yes)
-    SRC += $(PROTOCOL_DIR)/serial_soft.c
-endif
-
-ifeq ($(strip $(SERIAL_MOUSE_USE_UART)), yes)
-    SRC += $(PROTOCOL_DIR)/serial_uart.c
-endif
-
 ifeq ($(strip $(USB_HID_ENABLE)), yes)
     include $(TMK_DIR)/protocol/usb_hid.mk
 endif
diff --git a/tmk_core/protocol/serial_mouse.h b/tmk_core/protocol/serial_mouse.h
deleted file mode 100644
index cb83cf4f6221..000000000000
--- a/tmk_core/protocol/serial_mouse.h
+++ /dev/null
@@ -1,29 +0,0 @@
-/*
-Copyright 2014 Robin Haberkorn <robin.haberkorn@googlemail.com>
-
-This program is free software: you can redistribute it and/or modify
-it under the terms of the GNU General Public License as published by
-the Free Software Foundation, either version 2 of the License, or
-(at your option) any later version.
-
-This program is distributed in the hope that it will be useful,
-but WITHOUT ANY WARRANTY; without even the implied warranty of
-MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
-GNU General Public License for more details.
-
-You should have received a copy of the GNU General Public License
-along with this program.  If not, see <http://www.gnu.org/licenses/>.
-*/
-
-#pragma once
-
-#include <stdint.h>
-
-#include "serial.h"
-
-static inline uint8_t serial_mouse_init(void) {
-    serial_init();
-    return 0;
-}
-
-void serial_mouse_task(void);
diff --git a/tmk_core/protocol/serial_mouse_microsoft.c b/tmk_core/protocol/serial_mouse_microsoft.c
deleted file mode 100644
index eff0bf6e45f8..000000000000
--- a/tmk_core/protocol/serial_mouse_microsoft.c
+++ /dev/null
@@ -1,113 +0,0 @@
-/*
-Copyright 2014 Robin Haberkorn <robin.haberkorn@googlemail.com>
-
-This program is free software: you can redistribute it and/or modify
-it under the terms of the GNU General Public License as published by
-the Free Software Foundation, either version 2 of the License, or
-(at your option) any later version.
-
-This program is distributed in the hope that it will be useful,
-but WITHOUT ANY WARRANTY; without even the implied warranty of
-MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
-GNU General Public License for more details.
-
-You should have received a copy of the GNU General Public License
-along with this program.  If not, see <http://www.gnu.org/licenses/>.
-*/
-
-#include <stdint.h>
-#include <avr/io.h>
-#include <util/delay.h>
-
-#include "serial.h"
-#include "serial_mouse.h"
-#include "report.h"
-#include "host.h"
-#include "timer.h"
-#include "print.h"
-#include "debug.h"
-
-#ifdef MAX
-#    undef MAX
-#endif
-#define MAX(X, Y) ((X) > (Y) ? (X) : (Y))
-
-static void print_usb_data(const report_mouse_t *report);
-
-void serial_mouse_task(void) {
-    /* 3 byte ring buffer */
-    static uint8_t buffer[3];
-    static int     buffer_cur = 0;
-
-    static report_mouse_t report = {};
-
-    int16_t rcv;
-
-    rcv = serial_recv2();
-    if (rcv < 0) /* no new data */
-        return;
-
-    if (debug_mouse) xprintf("serial_mouse: byte: %04X\n", rcv);
-
-    /*
-     * If bit 6 is one, this signals the beginning
-     * of a 3 byte sequence/packet.
-     */
-    if (rcv & (1 << 6)) buffer_cur = 0;
-
-    buffer[buffer_cur] = (uint8_t)rcv;
-
-    if (buffer_cur == 0 && buffer[buffer_cur] == 0x20) {
-        /*
-         * Logitech extension: This must be a follow-up on
-         * the last 3-byte packet signaling a middle button click
-         */
-        report.buttons |= MOUSE_BTN3;
-        report.x = report.y = 0;
-
-        print_usb_data(&report);
-        host_mouse_send(&report);
-        return;
-    }
-
-    buffer_cur++;
-
-    if (buffer_cur < 3) return;
-    buffer_cur = 0;
-
-    /*
-     * parse 3 byte packet.
-     * NOTE: We only get a complete packet
-     * if the mouse moved or the button states
-     * change.
-     */
-    report.buttons = 0;
-    if (buffer[0] & (1 << 5)) report.buttons |= MOUSE_BTN1;
-    if (buffer[0] & (1 << 4)) report.buttons |= MOUSE_BTN2;
-
-    report.x = (buffer[0] << 6) | buffer[1];
-    report.y = ((buffer[0] << 4) & 0xC0) | buffer[2];
-
-    /* USB HID uses values from -127 to 127 only */
-    report.x = MAX(report.x, -127);
-    report.y = MAX(report.y, -127);
-
-#if 0
-    if (!report.buttons && !report.x && !report.y) {
-        /*
-         * Microsoft extension: Middle mouse button pressed
-         * FIXME: I don't know how exactly this extension works.
-         */
-        report.buttons |= MOUSE_BTN3;
-    }
-#endif
-
-    print_usb_data(&report);
-    host_mouse_send(&report);
-}
-
-static void print_usb_data(const report_mouse_t *report) {
-    if (!debug_mouse) return;
-
-    xprintf("serial_mouse usb: [%02X|%d %d %d %d]\n", report->buttons, report->x, report->y, report->v, report->h);
-}
diff --git a/tmk_core/protocol/serial_mouse_mousesystems.c b/tmk_core/protocol/serial_mouse_mousesystems.c
deleted file mode 100644
index 0ec2b0399aab..000000000000
--- a/tmk_core/protocol/serial_mouse_mousesystems.c
+++ /dev/null
@@ -1,119 +0,0 @@
-/*
-Copyright 2014 Robin Haberkorn <robin.haberkorn@googlemail.com>
-
-This program is free software: you can redistribute it and/or modify
-it under the terms of the GNU General Public License as published by
-the Free Software Foundation, either version 2 of the License, or
-(at your option) any later version.
-
-This program is distributed in the hope that it will be useful,
-but WITHOUT ANY WARRANTY; without even the implied warranty of
-MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE.  See the
-GNU General Public License for more details.
-
-You should have received a copy of the GNU General Public License
-along with this program.  If not, see <http://www.gnu.org/licenses/>.
-*/
-
-#include <stdint.h>
-#include <avr/io.h>
-#include <util/delay.h>
-
-#include "serial.h"
-#include "serial_mouse.h"
-#include "report.h"
-#include "host.h"
-#include "timer.h"
-#include "print.h"
-#include "debug.h"
-
-#ifdef MAX
-#    undef MAX
-#endif
-#define MAX(X, Y) ((X) > (Y) ? (X) : (Y))
-
-//#define SERIAL_MOUSE_CENTER_SCROLL
-
-static void print_usb_data(const report_mouse_t *report);
-
-void serial_mouse_task(void) {
-    /* 5 byte ring buffer */
-    static uint8_t buffer[5];
-    static int     buffer_cur = 0;
-
-    int16_t rcv;
-
-    report_mouse_t report = {0, 0, 0, 0, 0};
-
-    rcv = serial_recv2();
-    if (rcv < 0) /* no new data */
-        return;
-
-    if (debug_mouse) xprintf("serial_mouse: byte: %04X\n", rcv);
-
-    /*
-     * Synchronization: mouse(4) says that all
-     * bytes but the first one in the packet have
-     * bit 7 == 0, but this is untrue.
-     * Therefore we discard all bytes up to the
-     * first one with the characteristic bit pattern.
-     */
-    if (buffer_cur == 0 && (rcv >> 3) != 0x10) return;
-
-    buffer[buffer_cur++] = (uint8_t)rcv;
-
-    if (buffer_cur < 5) return;
-    buffer_cur = 0;
-
-#ifdef SERIAL_MOUSE_CENTER_SCROLL
-    if ((buffer[0] & 0x7) == 0x5 && (buffer[1] || buffer[2])) {
-        /* USB HID uses only values from -127 to 127 */
-        report.h = MAX((int8_t)buffer[1], -127);
-        report.v = MAX((int8_t)buffer[2], -127);
-
-        print_usb_data(&report);
-        host_mouse_send(&report);
-
-        if (buffer[3] || buffer[4]) {
-            report.h = MAX((int8_t)buffer[3], -127);
-            report.v = MAX((int8_t)buffer[4], -127);
-
-            print_usb_data(&report);
-            host_mouse_send(&report);
-        }
-
-        return;
-    }
-#endif
-
-    /*
-     * parse 5 byte packet.
-     * NOTE: We only get a complete packet
-     * if the mouse moved or the button states
-     * change.
-     */
-    if (!(buffer[0] & (1 << 2))) report.buttons |= MOUSE_BTN1;
-    if (!(buffer[0] & (1 << 1))) report.buttons |= MOUSE_BTN3;
-    if (!(buffer[0] & (1 << 0))) report.buttons |= MOUSE_BTN2;
-
-    /* USB HID uses only values from -127 to 127 */
-    report.x = MAX((int8_t)buffer[1], -127);
-    report.y = MAX(-(int8_t)buffer[2], -127);
-
-    print_usb_data(&report);
-    host_mouse_send(&report);
-
-    if (buffer[3] || buffer[4]) {
-        report.x = MAX((int8_t)buffer[3], -127);
-        report.y = MAX(-(int8_t)buffer[4], -127);
-
-        print_usb_data(&report);
-        host_mouse_send(&report);
-    }
-}
-
-static void print_usb_data(const report_mouse_t *report) {
-    if (!debug_mouse) return;
-
-    xprintf("serial_mouse usb: [%02X|%d %d %d %d]\n", report->buttons, report->x, report->y, report->v, report->h);
-}