diff --git a/pyquil/api/_qvm.py b/pyquil/api/_qvm.py
index 309afaa14..c93873435 100644
--- a/pyquil/api/_qvm.py
+++ b/pyquil/api/_qvm.py
@@ -136,7 +136,7 @@ def execute(
             executable = apply_noise_model(executable, self.noise_model)
 
         result = qvm.run(
-            executable.out(),
+            executable.out(calibrations=False),
             trials,
             addresses,
             memory_map or {},
diff --git a/pyquil/api/_wavefunction_simulator.py b/pyquil/api/_wavefunction_simulator.py
index a2378cd7c..0a274b1e2 100644
--- a/pyquil/api/_wavefunction_simulator.py
+++ b/pyquil/api/_wavefunction_simulator.py
@@ -91,7 +91,7 @@ def wavefunction(self, quil_program: Program, memory_map: Optional[MemoryMap] =
             quil_program = self.augment_program_with_memory_values(quil_program, memory_map)
 
         request = qvm.api.WavefunctionRequest(
-            quil_program.out(),
+            quil_program.out(calibrations=False),
             self.measurement_noise,
             self.gate_noise,
             self.random_seed,