LogFC calculation in FindMarkers

[person-c]

Hello, when I manully calculated the log2FC, I found the result was different from the FindMarkers function; When I check the soure code I found this function calculating logFC like this:

I tested this code manully, and its result were the same as the FindMarkers function:

However, what I previoussly thought the meaning of logFC is the log(avg_A/avg_B) ; this caculation seems not like this(I know the add 1 operation to avod zero but don't understand why calculate e(x)), are there any reasons behind this?; And I found there was a big difference between this function's result and results from direct calculation;

log2(mean(MNRAKO)/mean(MNRALC)) = -0.16

This will cause a different result when I choose the logFC cretia to filter some genes. Which one should I choose better?

[morallawwithin]

See #6701

[person-c]

See #6701

Thanks!