diff --git a/Modules/IO/NIFTI/src/itkNiftiImageIO.cxx b/Modules/IO/NIFTI/src/itkNiftiImageIO.cxx
index a2bf41a88266..fd70de83a2a2 100644
--- a/Modules/IO/NIFTI/src/itkNiftiImageIO.cxx
+++ b/Modules/IO/NIFTI/src/itkNiftiImageIO.cxx
@@ -994,6 +994,29 @@ NiftiImageIO::SetImageIOMetadataFromNIfTI()
   std::ostringstream intent_name;
   intent_name << nim->intent_name;
   EncapsulateMetaData<std::string>(thisDic, "intent_name", intent_name.str());
+
+  // The below were added after ITK 5.3rc2.
+
+  EncapsulateMetaData<float>(thisDic, "qfac", nim->qfac);
+
+  std::vector<float> qto_xyz;
+  qto_xyz.push_back(nim->qto_xyz.m[0][0]);
+  qto_xyz.push_back(nim->qto_xyz.m[0][1]);
+  qto_xyz.push_back(nim->qto_xyz.m[0][2]);
+  qto_xyz.push_back(nim->qto_xyz.m[0][3]);
+  qto_xyz.push_back(nim->qto_xyz.m[1][0]);
+  qto_xyz.push_back(nim->qto_xyz.m[1][1]);
+  qto_xyz.push_back(nim->qto_xyz.m[1][2]);
+  qto_xyz.push_back(nim->qto_xyz.m[1][3]);
+  qto_xyz.push_back(nim->qto_xyz.m[2][0]);
+  qto_xyz.push_back(nim->qto_xyz.m[2][1]);
+  qto_xyz.push_back(nim->qto_xyz.m[2][2]);
+  qto_xyz.push_back(nim->qto_xyz.m[2][3]);
+  qto_xyz.push_back(nim->qto_xyz.m[3][0]);
+  qto_xyz.push_back(nim->qto_xyz.m[3][1]);
+  qto_xyz.push_back(nim->qto_xyz.m[3][2]);
+  qto_xyz.push_back(nim->qto_xyz.m[3][3]);
+  EncapsulateMetaData<std::vector<float>>(thisDic, "qto_xyz", qto_xyz);
 }
 
 void