| TAH Drug Code | INAL |
|---|---|
| Indications | Complete or partial reversal of narcotic depression including respiratory depression, induced by opioids including natural & synthetic narcotics & narcotic-antagonist analgesics. Diagnosis of suspected acute opioid overdosage |
| Dosing | (Micromedex) Overdose of opiate, known or suspected: (Injection solution) 0.4-2 mg IV, repeat every 2-3 minutes as needed; if no response after 10 mg, reconsider diagnosis of opioid toxicity; may administer IM or SC if IV route is unavailable. |
| Hepatic Impairment | Dose adjustment not necessary |
| Renal Impairment | Dose adjustment not necessary |
| Contraindications | Hypersensitivity to any component of the formulation. |
| Adverse Effects | Hypertension, hypotension, ventricular tachycardia, pulmonary oedema, tremulousness, nausea/vomiting, sweating. |
| Pregnancy | Compatible |
| Lactation | No (Limited) Human Data - Probably Compatible |
| More Info | UpToDate |