| Adverse Effects |
>10%: Cardiovascular: Hypotension (5% to 13%) Central nervous system: Headache (10%) Gastrointestinal: Nausea (26%), vomiting (11% to 15%) Local: Pain at injection site (48% to 52%) 1% to 10%: Cardiovascular: Hypertension (9%), prolonged QT interval on ECG (6%), bradycardia (5%), tachycardia (2% to 5%) Central nervous system: Anesthesia complication (1% to 9%), chills (7%), incisional pain (4% to 6%), dizziness (3% to 6%), insomnia (5%), hypoesthesia (3%), anxiety (1% to 3%), restlessness (1% to 2%), depression (2%) Dermatologic: Pruritus (3%), erythema (2%) Endocrine & metabolic: Hypocalcemia (2%) Gastrointestinal: Abdominal pain (4% to 6%), flatulence (3%), xerostomia (2%) Hematologic & oncologic: Wound hemorrhage (2%), decreased red blood cells (1% to 2%) Neuromuscular & skeletal: Limb pain (6%), musculoskeletal pain (2%), myalgia (2%), increased creatine phosphokinase (1% to 2%), neuromuscular blockade (<=2%; reoccurrence) Respiratory: Cough (3% to 8%) Miscellaneous: Fever (5% to 9%), procedural complications (8%), hysterectomy (2%) <1%, postmarketing, and/or case reports: Anaphylactic shock, anaphylactoid reaction, anaphylaxis, atrial fibrillation, atrioventricular block, bronchospasm, dyspnea, extrasystoles, hypersensitivity reaction, laryngospasm, pulmonary edema, ST segment changes on ECG, supraventricular extrasystole, supraventricular tachycardia, urticaria, ventricular fibrillation, ventricular tachycardia, wheezing |