| TAH Drug Code | ONEO |
|---|---|
| Indications | Bowel sterilisation before surgery; to reduce the bacterial population of the colon in hepatic failure. |
| Dosing | (仿單) Adults: Intestinal infection: 500 mg orally Q6H. Bowel preparation, pre-GI surgery: 1 g orally Q6H for 1-3 days. (熱病) Hepatic encephalopathy: 500-2000 mg Q6-8H for 5-6 days; seek safer alternative for longer use. |
| Hepatic Impairment | Dose adjustment not necessary |
| Renal Impairment | Dose adjustment required |
| Contraindications | Intestinal obstruction; myasthenia gravis. |
| Adverse Effects | Vestibular & auditory damage, nephrotoxicity, GI disturbances. |
| Pregnancy | Human Data Suggest Low Risk |
| Lactation | No (Limited) Human Data - Probably Compatible |
| More Info | UpToDate |