| Dosing |
Adult: 250mg once a day. Children above 3 years old: weight<20kg: 62.5mg once a day, weight 20-40kg: 125mg once a day, weight>40kg: 250mg once a day. Treatment duration Cutaneous infection: Feet tinea(between the toes, pachyderm) 2-6weeks. Ringworm of the body tinea cruris 2-4weeks. Cutaneous candida infection 2-4weeks. Infections of scalp hair: Tinea capitis 4weeks. Tinea capitis occurs mostly in children. Onychomycosis most patients need a 6-12weeks period of treatment. In Fingernail onychomycosis, most patients need 6 weeks. In toenail onychomycosis, most patients need 12 weeks. |
| Adverse Effects |
Common Dermatologic: Rash (oral granules, 2% ; oral tablets, 5.6% ) Gastrointestinal: Diarrhea (oral granules, 3% ; oral tablets, 5.6% ), Disorder of taste (oral tablets, 2.8% ), Indigestion (oral tablets, 4.3% ), Nausea (oral granules, 2% ; oral tablets, 2.6% ), Vomiting (oral granules, 5% ) Hepatic: Increased liver enzymes (oral tablets, 3.3% ) Neurologic: Headache (oral granules, 7% ; oral tablet, 12.9% ) Respiratory: Cough (oral granules, 6% ), Nasopharyngitis (oral granules, 10% ), Upper respiratory infection (oral granules, 5% ) Other: Fever (oral granules, 7% ) Serious Dermatologic: Cutaneous lupus erythematosus, Erythema multiforme, Generalized exanthematous pustulosis, acute, Stevens-Johnson syndrome, Toxic epidermal necrolysis Hematologic: Neutropenic disorder (Severe), Thrombotic microangiopathy Hepatic: Liver failure Immunologic: Drug reaction with eosinophilia and systemic symptoms, Systemic lupus erythematosus Otic: Hearing loss |