| TAH Drug Code | OXOFL |
|---|---|
| Indications | Treatment of acute infections of type A and B influenza viruses for adults and children. |
| Dosing | Influenza, uncomplicated: Administer within 48 hours of influenza symptom onset. Adults (1) 20kg to <80kg: 40mg as a single oral dose; (2) >=80kg: 80mg as a single oral dose. 5 Years or Older (1)<20kg: 2mg/kg as a single oral dose; (2) 20kg to <80kg: 40mg as a single oral dose; (3) >=80kg: 80mg as a single oral dose. Influenza, postexposure prophylaxis: Administer within 48 hours of exposure. Adults (1) 20kg to <80kg: 40mg as a single oral dose; (2) >=80kg: 80mg as a single oral dose. 5 Years or Older (1) <20kg: 2mg/kg as a single dose; (2) 20kg to <80kg: 40mg as a single oral dose; (3) >=80kg: 80mg as a single oral dose. |
| Hepatic Impairment | Dose adjustment not necessary |
| Renal Impairment | Dose adjustment not necessary |
| Contraindications | History of hypersensitivity to baloxavir marboxil or any of its ingredients. |
| Adverse Effects | Common: Diarrhea (3-5%), Nausea (2%), Vomiting (Pediatric, 5% .), Headache (1%), Bronchitis (3%), Sinusitis (2%) |
| Pregnancy | Unknown |
| Lactation | Unknown |
| More Info | UpToDate |