| TAH Drug Code | OCODI |
|---|---|
| Indications | Symptomatic relief of mild to moderate severe pain, suppress hyperactive or nonproductive cough. |
| Dosing | Analgesic: Adult 15-60 mg qid. Children and Adolescents: Pain management; analgesia: 0.5-1 mg/kg/dose every 4-6 hours as needed; maximum single dose: 60 mg. Note: Do not use for postoperative tonsillectomy and/or adenoidectomy pain management. Antitussive: Adult Oral: 7.5 to 120 mg/day as a single dose or in divided doses; Note: The American College of Chest Physicians does not recommend the routine use of codeine as an antitussive in patients with upper respiratory infections. |
| Hepatic Impairment | Dose adjustment not necessary |
| Renal Impairment | Dose adjustment required |
| Contraindications | Hypersensitivity to opiates, acute respiratory depression, acute asthma, increased intracranial pressure, COPD, head injury, paralytic ileus, acute alcoholism, hepatic or renal dysfunction, phaeochromocytoma. |
| Adverse Effects | Common: Sweating, Constipation, Nausea, Vomiting, Dizziness, Lightheadedness, Sedated, Somnolence, Dyspnea Serious: Cardiac arrest, Disorder of cardiovascular system, Circulatory Depression, Shock, Adrenal insufficiency, Pancreatitis, Deficiency of testosterone biosynthesis, Respiratory arrest, Respiratory depression, Serotonin syndrome |
| Pregnancy | Human (and Animal) Data Suggest Risk |
| Lactation | Human Data Suggest Potential Toxicity |
| More Info | UpToDate |