| TAH Drug Code | OBUSR |
|---|---|
| Indications | Anxiety. |
| Dosing | Initial dose:15mg/day(5mg TID). If needed, increased by 5mg/day every 2~3 days. General dose:20-30mg/day in divided doses. maximum dose: 60mg/day. |
| Hepatic Impairment | Dose adjustment not necessary |
| Renal Impairment | Dose adjustment not necessary |
| Contraindications | Epilepsy, severe hepatic or renal impairment, pregnancy & lactation. Breast feeding. |
| Adverse Effects | Dizziness, nausea, headache, nervousness, lightheadedness, excitement; rarely tachycardia, palpitations, chest pain, drowsiness, tinnitus. Gastrointestinal: Nausea (3%) Neurologic: Asthenia (2%), Confusion (2%), Dizziness (9%), Excitement (2%), Headache (3%), Numbness (2%) Ophthalmic: Blurred vision (2%) Psychiatric: Feeling angry (2%), Feeling nervous (4%), Hostile behavior (2%) |
| Pregnancy | No (Limited) Human Data – Animal Data Suggest Low Risk |
| Lactation | No (Limited) Human Data - Potential Toxicity |
| More Info | UpToDate |