| TAH Drug Code | OEVO |
|---|---|
| Indications | Treatment of symptoms of dry mouth in patients with Sjogren's Syndrome. |
| Dosing | Sjogren's syndrome - Xerostomia: 30 mg PO TID. |
| Hepatic Impairment | Dose adjustment not necessary |
| Renal Impairment | Dose adjustment not necessary |
| Contraindications | Uncontrolled asthma, when miosis is undesirable eg. in acute iritis & in narrow-angle glaucoma. |
| Adverse Effects | Excessive sweating, nausea, rhinitis, diarrhea, excessive salivation, urinary frequency, asthenia, flushing, palpitation, dyspepsia, abdominal pain, UTI, cough, vomiting. (Common) Dermatologic: Sweating symptom Gastrointestinal: Diarrhea, Excessive salivation, Indigestion, Nausea, Vomiting Renal: Urinary tract infectious disease Respiratory: Bronchitis, Cough, Rhinitis, Sinusitis, Upper respiratory infection (Serious) Cardiovascular: Chest pain (1-3%), Edema (1-3%), Palpitations (1-3%) Ophthalmic: Eye / vision finding (1-3%) |
| Pregnancy | No (Limited) Human Data – No Relevant Animal Data |
| Lactation | No (Limited) Human Data - Potential Toxicity |
| More Info | UpToDate |