| TAH Drug Code | OFLU |
|---|---|
| Indications | As diuretics, antihypertensive. |
| Dosing | Antihypertensive: 2-4 mg once daily. Initial dose: 2-4 mg BID. Maintenance: 2 mg once daily. Diuretic: 4 mg once daily. Initial dose: 4 mg BID. Maintenance: 2 mg BID. |
| Hepatic Impairment | Dose adjustment not necessary |
| Renal Impairment | Dose adjustment not necessary |
| Contraindications | Anuria, hypersensitivity to sulfonamides. |
| Adverse Effects | Arrhythmias, orthostatic hypotension, dizziness, headache, paresthesias, vertigo, xanthopsia, hyperglycemia, hyperuricemia, hypercalcemia, hypokalemia, hyponatremia, anorexia, cramping, constipation, diarrhea, gastric irritation, jaundice, pancreatitis, nausea & vomiting, glycosuria, muscle weakness, muscle spasm, necrotizing angiitis, photosensitivity, purpura, rash, urticaria, agranulocytosis, aplastic anemia, leukopenia, thrombocytopenia. |
| Pregnancy | Unknown |
| Lactation | Unknown |
| More Info | UpToDate |