| TAH Drug Code | ODOX4 |
|---|---|
| Indications | Hypertension. Benign prostatic hyperplasia.(B023711100) |
| Dosing | Extended release tablet should be swallowed whole; do not crush, cut, chew, or divide. Adult usual dosage: 4 mg QD, may increase if necessary at the 4-week interval to a maximum 8 mg QD. |
| Hepatic Impairment | Dose adjustment not necessary |
| Renal Impairment | Dose adjustment not necessary |
| Contraindications | Patients with known hypersensitivity to quinazolines, doxazosin or any of the excipients of Doxaben/Doxaben XL. |
| Adverse Effects | Dizziness, headache, fatigue, vertigo, edema & asthenia. Cardiovascular: Edema (2.7% to 4%), Hypotension (1.7%-10%) Gastrointestinal: Nausea (1.2% to 4.3%) Neurologic: Dizziness (5.3% to 19%), Headache (4% to 15.8%), Somnolence (1.2% to 5%), Vertigo (1.5% to 7%) Other: Fatigue (8% to 12%) |
| Pregnancy | No (Limited) Human Data – Animal Data Suggest Moderate Risk |
| Lactation | No (Limited) Human Data - Potential Toxicity |
| More Info | UpToDate |