| TAH Drug Code | OZUL |
|---|---|
| Indications | Primary hypercholesterolemia and mixed dyslipidemia |
| Dosing | Adult: 1-4 mg orally once daily. Dose adjustments should be made at intervals of 4 weeks. |
| Hepatic Impairment | Dose adjustment required |
| Renal Impairment | Dose adjustment required |
| Contraindications | Active liver disease, Breastfeeding, Concomitant use of cyclosporine, Hypersensitivity to pitavastatin or any other component of the product, Pregnancy, Unexplained persistent elevations of serum transaminase levels. |
| Adverse Effects | Common Gastrointestinal: Constipation (1.5% to 3.6% ), Diarrhea (1.5% to 2.6% ) Musculoskeletal: Backache (1.4% to 3.9% ), Myalgia (1.9% to 3.1% ), Pain in limb (0.6% to 2.3% ) Serious Endocrine metabolic: Disorder of glucose regulation Hepatic: ALT/SGPT level raised (0.5% ), AST/SGOT level raised, Increased liver enzymes, Liver failure Musculoskeletal: Disorder of muscle, Statin-associated, Increased creatine kinase level (1.9% ), Rhabdomyolysis |
| Pregnancy | Contraindicated – 1st Trimester |
| Lactation | Contraindicated |
| More Info | UpToDate |