| TAH Drug Code | ESOO3 |
|---|---|
| Indications | Rosacea (Soolantra cream): Treatment of inflammatory lesions of rosacea in adult patients. |
| Dosing | Rosacea Topical Apply to each affected area (eg, forehead, chin, nose, each cheek) once daily, maximum for 4 month |
| Hepatic Impairment | Dose adjustment not necessary |
| Renal Impairment | Dose adjustment not necessary |
| Contraindications | Hypersensitivity (rare). |
| Adverse Effects | 1% to 10%: Central nervous system: Localized burning (<=1%) Dermatologic: Skin irritation (<=1%) <1% (Limited to important or life-threatening): Conjunctivitis, eye irritation, ocular hyperemia, seborrheic dermatitis of scalp, xeroderma |
| Pregnancy | Human Data Suggest Low Risk |
| Lactation | No (Limited) Human Data - Probably Compatible |
| More Info | UpToDate |
| TAH Drug Code | OSTRM |
|---|---|
| Indications | Scabies, Onchocerciasis, Intestinal strongyloidiasis. |
| Dosing | Scabies: Oral: 200 mcg/kg as a single dose, dose could follow (3mg/TAB): 15-24kg:1TAB; 25-35kg: 2 TAB; 36-50kg:3 TAB; 51-65kg: 4TAB; 66-79kg: 5 TAB; >=80kg:200 mcg/kg. If the symptoms of infection are still present and the test is positive, Could be administered again after 8-15 days. Onchocerciasis: Oral: 200 mcg/kg as a single dose, dose could follow (3mg/TAB): 15-24kg:1 TAB; 25-35kg:2 TAB; 36-50kg:3 TAB; 51-65kg: 4 TAB; 66-79kg: 5 TAB; >=80kg:200 mcg/kg. Intestinal strongyloidiasis: Oral: 200 mcg/kg as a single dose, dose could follow (3mg/TAB): 15-24kg:1TAB ; 25-35kg:2 TAB; 36-50kg:3 TAB ; 51-65kg:4 TAB ; 66-79kg:5 TAB ; >=80kg:200 mcg/kg. |
| Hepatic Impairment | Dose adjustment not necessary |
| Renal Impairment | Dose adjustment not necessary |
| Contraindications | Hypersensitivity to oral ivermectin or any other component of the product. Specific contraindications have not been determined for topical ivermectin. |
| Adverse Effects | Common Dermatologic: Pruritus (2.8% ), Urticaria (Oral, 0.9% ) Neurologic: Dizziness (2.8% ) Serious Immunologic: Mazzotti reaction Neurologic: Seizure |
| Pregnancy | No (Limited) Human Data – Animal Data Suggest Low Risk |
| Lactation | No (Limited) Human Data - Probably Compatible |
| More Info | UpToDate |