| TAH Drug Code | OCLOM5 |
|---|---|
| Indications | Induction of ovulation for infertility caused by ovulatory disorders. |
| Dosing | Female infertility due to ovulatory disorder: 50 mg orally daily for 5 days starting on the 5th day of menstrual cycle or at any time if no recent uterine bleeding; if ovulation has not occurred, 100 mg (single daily dose) for 5 days can be initiated next menstrual cycle. Discontinue medication if no ovulatory menstruation occurs after three cycles. |
| Hepatic Impairment | Dose adjustment not necessary |
| Renal Impairment | Dose adjustment not necessary |
| Contraindications | No Data |
| Adverse Effects | Common: Flushing, Vasomotor (10.4%), Abdominal bloating, Abdominal discomfort, Nausea and vomiting, Swollen abdomen, Headache (1.3%), Visual disturbance (1.5%), Pain of breast (2.1%). Serious: Pancreatitis, acute, Functional visual loss, Psychotic disorder, Disorder of menstruation (1.3%), Hyperstimulation of ovaries, Hypertrophy of ovary (13.6%), Ovarian cancer. |
| Pregnancy | Contraindicated |
| Lactation | No (Limited) Human Data - Potential Toxicity |
| More Info | UpToDate |