| TAH Drug Code | OXYZ |
|---|---|
| Indications | To treat allergy symptoms in adults and children aged six and above caused by allergic rhinitis, chronic urticaria, and other allergic conditions. This includes various symptoms caused by persistent allergic rhinitis. |
| Dosing | Adult & children >= 6 years 5 mg once daily, before or after meals. Not recommended for children under six. |
| Hepatic Impairment | Dose adjustment not necessary |
| Renal Impairment | Dose adjustment required |
| Contraindications | Hypersensitivity to levocetirizine, cetirizine, or any component of the product; reactions ranging from urticaria to anaphylaxis have been observed. End-stage renal disease with a CrCl less than 10 mL/min or requiring dialysis. Pediatric patients between 6 months and 11 years old with renal impairment. |
| Adverse Effects | Common: Dry mouth, Headache, Somnolence, Abdominal pain, Migraine, Constipation (Infants, 7%), Diarrhea (Infants, 13%; pediatrics, 4%), Painful teething (Infants, 6.7%), Vomiting (Pediatrics, 4%), Xerostomia (Adults and adolescents, 2-3%), Otitis media (Pediatric, 3%), Nasopharyngitis (Adults and adolescents, 4-6%), Pharyngitis (Adults and adolescents, 1-2%), Fever (Pediatric, 4%) Serious: Asthenia, Somnolence (4.4-6%), Urinary retention, Fatigue (Adults and adolescents, 1-4%) |
| Pregnancy | No (Limited) Human Data – Animal Data Suggest Low Risk |
| Lactation | No (Limited) Human Data - Probably Compatible |
| More Info | UpToDate |