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mycophenolate_mofetil.md

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Mycophenolate mofetil

Cellcept 250mg

臨採
TAH Drug Code OCELL
Indications Prophylaxis of acute organ rejection in patients receiving allogeneic renal, cardiac & hepatic transplants, concomitantly w/ cyclosporin & corticosteroids. Induction & maintenance treatment of lupus nephritis, concomitantly w/ corticosteroids.
Dosing Renal transplant 1 g BID. Cardiac & hepatic transplant 1.5 g BID. Lupus nephritis induction dose 0.75-1.5 g BID, maintenance dose 0.25-1 g BID.
Hepatic Impairment Dose adjustment required
Renal Impairment Dose adjustment required
Contraindications Hypersensitivity to mycophenolate mofetil or mycophenolic acid (MPA).
Adverse Effects Diarrhoea, dyspepsia, vomiting, elevated liver function test, acne, leucopenia, sepsis, certain infections; CV, metabolic, CNS & musculoskeletal events.
Pregnancy Human (and Animal) Data Suggest Risk
Lactation Contraindicated
More Info UpToDate