TAH Drug Code | OCELL |
---|---|
Indications | Prophylaxis of acute organ rejection in patients receiving allogeneic renal, cardiac & hepatic transplants, concomitantly w/ cyclosporin & corticosteroids. Induction & maintenance treatment of lupus nephritis, concomitantly w/ corticosteroids. |
Dosing | Renal transplant 1 g BID. Cardiac & hepatic transplant 1.5 g BID. Lupus nephritis induction dose 0.75-1.5 g BID, maintenance dose 0.25-1 g BID. |
Hepatic Impairment | Dose adjustment required |
Renal Impairment | Dose adjustment required |
Contraindications | Hypersensitivity to mycophenolate mofetil or mycophenolic acid (MPA). |
Adverse Effects | Diarrhoea, dyspepsia, vomiting, elevated liver function test, acne, leucopenia, sepsis, certain infections; CV, metabolic, CNS & musculoskeletal events. |
Pregnancy | Human (and Animal) Data Suggest Risk |
Lactation | Contraindicated |
More Info | UpToDate |