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calcium_chloride_and_dextrose.md

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Calcium Chloride + Dextrose

VitaCAL inj 5.44mEq/20mL (5.44mg/mL)

TAH Drug Code IVIT
Indications Treatment of hypocalcemia and conditions secondary to hypocalcemia (eg, tetany, seizures, arrhythmias); emergent treatment of severe hypermagnesemia.
Dosing Vitacal inj (Calcium chloride 400mg + Glucose.H2O 2gm / 20mL) Adult Dosing --Hypocalcemia: 200 mg to 1 g calcium chloride (55 to 273 mg elemental calcium) IV every 1 to 3 days. --Cardiac arrest or cardiotoxicity in the presence of hyperkalemia, hypocalcemia, or hypermagnesemia: IV: 500-1000 mg over 2-5 minutes; may repeat as necessary. --Beta-blocker overdose, refractory to glucagon and high-dose vasopressors (off-label use): IV: 20 mg/kg over 5-10 minutes followed by an infusion of 20 mg/kg/hour titrated to adequate hemodynamic response. --Calcium channel blocker overdose (off-label use): IV: Initial: 1000-2000 mg over 5 minutes; may repeat every 10-20 minutes with 3-4 additional doses or 1000 mg every 2-3 minutes until clinical effect is achieved; if favorable response obtained, consider IV infusion. IV infusion: 20-40 mg/kg/hour.
Hepatic Impairment No Data
Renal Impairment No Data
Contraindications Known or suspected digoxin toxicity; not recommended as routine treatment in cardiac arrest (includes asystole, ventricular fibrillation, pulseless ventricular tachycardia, or pulseless electrical activity). Ventricular fibrillation during cardiac resuscitation. Patient at risk of existing digitalis toxicity. No recommended for the treatment of asystole and electromechanical dissociation.
Adverse Effects Common: Burning sensation. Serious: Vasodilatation, Injection site extravasation.
Pregnancy No Data
Lactation Contraindicated
More Info UpToDate