| TAH Drug Code | OVGR1 |
|---|---|
| Indications | Treatment of erectile dysfunction. |
| Dosing | Erectile dysfunction: Sildenafil 25 to 100 mg (50 mg usual dose) orally 1 hour (range 0.5 to 4 hours) prior to sexual activity; the maximum frequency of administration once daily. |
| Hepatic Impairment | Dose adjustment required |
| Renal Impairment | Dose adjustment required |
| Contraindications | Patients who use nitric oxide donors or nitrates. Viagra should not be used in men for whom sexual activity is inadvisable (patients with severe CV disorders eg unstable angina or severe cardiac failure). Severe hepatic impairment, hypotension (< 90/50 mm Hg) or hypertension (> 170/100 mm Hg), recent history of stroke or MI, known hereditary degenerative retinal disorders such as retinitis pigmentosa. Not indicated for women. |
| Adverse Effects | Common: Flushing (9-19%), Indigestion (3-17%), Headache (Erectile dysfunction, 16-28% ; pulmonary arterial hypertension, 46%), Insomnia (erectile dysfunction, less than 2%), Visual disturbance (erectile dysfunction, 1-11%), Bleeding from nose (pulmonary arterial hypertension, 3-9%), Nasal congestion (erectile dysfunction, 4-9%) Serious: Cardiovascular morbidity, Myocardial infarction, Sickle cell anemia with vasoocclusive crisis, Non-arteritic ischemic optic neuropathy, Retinal hemorrhage, Decreased hearing, Sudden onset (erectile dysfunction, less than 2%), Sudden hearing loss (erectile dysfunction, less than 2%), Priapism, Prolonged erection of penis |
| Pregnancy | No (Limited) Human Data – Animal Data Suggest Low Risk |
| Lactation | No (Limited) Human Data - Potential Toxicity |
| More Info | UpToDate |
| TAH Drug Code | OVGRO |
|---|---|
| Indications | Treatment of erectile dysfunction. |
| Dosing | Erectile dysfunction: Sildenafil 25 to 100 mg (50 mg usual dose) orally 1 hour (range 0.5 to 4 hours) prior to sexual activity; the maximum frequency of administration once daily. |
| Hepatic Impairment | Dose adjustment required |
| Renal Impairment | Dose adjustment required |
| Contraindications | Patients who use nitric oxide donors or nitrates. Viagra should not be used in men for whom sexual activity is inadvisable (patients with severe CV disorders eg unstable angina or severe cardiac failure). Severe hepatic impairment, hypotension (< 90/50 mm Hg) or hypertension (> 170/100 mm Hg), recent history of stroke or MI, known hereditary degenerative retinal disorders such as retinitis pigmentosa. Not indicated for women. |
| Adverse Effects | Common: Flushing (9-19%), Indigestion (3-17%), Headache (Erectile dysfunction, 16-28% ; pulmonary arterial hypertension, 46%), Insomnia (erectile dysfunction, less than 2%), Visual disturbance (erectile dysfunction, 1-11%), Bleeding from nose (pulmonary arterial hypertension, 3-9%), Nasal congestion (erectile dysfunction, 4-9%) Serious: Cardiovascular morbidity, Myocardial infarction, Sickle cell anemia with vasoocclusive crisis, Non-arteritic ischemic optic neuropathy, Retinal hemorrhage, Decreased hearing, Sudden onset (erectile dysfunction, less than 2%), Sudden hearing loss (erectile dysfunction, less than 2%), Priapism, Prolonged erection of penis |
| Pregnancy | No (Limited) Human Data – Animal Data Suggest Low Risk |
| Lactation | No (Limited) Human Data – Potential Toxicity(Mother) |
| More Info | UpToDate |